Fluorobenzenes
2-(2-Fluorophenyl)ethanol, 99%
CAS: 50919-06-7 Molecular Formula: C8H9FO Molecular Weight (g/mol): 140.16 MDL Number: MFCD00002887 InChI Key: HNIGZVZDWCTFPR-UHFFFAOYSA-N Synonym: 2-fluorophenethyl alcohol,2-2-fluorophenyl ethanol,2-2-fluorophenyl ethan-1-ol,benzeneethanol, 2-fluoro,2-fluorophenethylalcohol,2-2-fluoro-phenyl-ethanol,2-fluorobenzeneethanol,acmc-1axdv,o-fluorophenethyl alcohol,2-fluorophenylethyl alcohol PubChem CID: 2733296 IUPAC Name: 2-(2-fluorophenyl)ethanol SMILES: OCCC1=CC=CC=C1F
1-Bromo-3-chloro-5-fluorobenzene 98.0+%, TCI America™
CAS: 33863-76-2 Molecular Formula: C6H3BrClF Molecular Weight (g/mol): 209.442 MDL Number: MFCD00070747 InChI Key: GGMDFPMASIXEIR-UHFFFAOYSA-N Synonym: 3-chloro-5-fluorobromobenzene,1-bromo3-chloro-5-fluorobenzene,1-bromo-3-chloro-5-fluoro-benzene,benzene, 1-bromo-3-chloro-5-fluoro,1,3,5-fluorochlorobromobenzene,pubchem2261,acmc-209i3i,ksc494q7t,3-chloro-5-fluoro-bromobenzene,1-bromo-3-chloro-5-flurobenzene PubChem CID: 2736223 IUPAC Name: 1-bromo-3-chloro-5-fluorobenzene SMILES: C1=C(C=C(C=C1Cl)Br)F
1-Bromo-4-chloro-2-fluorobenzene, 98%
CAS: 1996-29-8 Molecular Formula: C6H3BrClF Molecular Weight (g/mol): 209.44 MDL Number: MFCD00079708 InChI Key: FPNVMCMDWZNTEU-UHFFFAOYSA-N Synonym: 4-chloro-2-fluorobromobenzene,2-fluoro-4-chlorobromobenzene,2-bromo-5-chlorofluorobenzene,1-bromo-4-chloro-2-fluoro-benzene,1-bromo-2-fluoro-4-chlorobenzene,2-bromo-5-chloro-1-fluorobenzene,benzene, 1-bromo-4-chloro-2-fluoro,pubchem3209,acmc-1bovk,2-bromo-5-chlorofluorbenzene PubChem CID: 137275 IUPAC Name: 1-bromo-4-chloro-2-fluorobenzene SMILES: FC1=CC(Cl)=CC=C1Br
4-Fluorobenzyl mercaptan, 96%
CAS: 15894-04-9 Molecular Formula: C7H7FS Molecular Weight (g/mol): 142.191 MDL Number: MFCD00040724 InChI Key: RKTRHMNWVZRZJQ-UHFFFAOYSA-N Synonym: 4-fluorobenzyl mercaptan,4-fluorophenyl methanethiol,4-fluorobenzylmercaptan,4-fluoro benzyl mercaptan,4-fluorobenzenemethanethiol,p-fluorotoluene-alpha-thiol,benzenemethanethiol, 4-fluoro,4-fluoro-phenyl-methanethiol,4-fluorobenzylthiol,4-fluorobenzyl thiol PubChem CID: 85171 IUPAC Name: (4-fluorophenyl)methanethiol SMILES: C1=CC(=CC=C1CS)F
eMolecules 4-AMINO-3,5-DIMETHOXYBENZOIC ACID | 123039-72-5 | MFCD03425882 | 1g
AstaTech | 4-AMINO-3,5-DIMETHOXYBENZOIC ACID | 1g | 273172160 | 76002 | 97.000 | 123039-72-5 | MFCD03425882 | 197.190 | C9H11NO4
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eMolecules Building Block Tool
eMolecules ChemScene / 5-(4-Fluorophenyl)-134-oxadiazole-2-carboxylic acid / 100mg / 714214795 / CS-0290860 / 0.000 / 944898-08-2 / MFCD10001469 / 208.148 / C9H5FN2O3
ChemScene / 5-(4-Fluorophenyl)-134-oxadiazole-2-carboxylic acid / 100mg / 714214795 / CS-0290860 / 0.000 / 944898-08-2 / MFCD10001469 / 208.148 / C9H5FN2O3
eMolecules ChemScene / ethyl 5-(4-fluorophenyl)-134-oxadiaZole-2-carboxylate / 100mg / 714125953 / CS-0236207 / 0.000 / 950259-82-2 / MFCD14716324 / 236.202 / C11H9FN2O3
ChemScene / ethyl 5-(4-fluorophenyl)-134-oxadiaZole-2-carboxylate / 100mg / 714125953 / CS-0236207 / 0.000 / 950259-82-2 / MFCD14716324 / 236.202 / C11H9FN2O3
eMolecules Ambeed / 3-Bromo-45-difluorobenzonitrile / 100mg / 600833270 / A195578 / / 1349715-72-5 / MFCD20233294 / 218.001 / C7H2BrF2N
Ambeed / 3-Bromo-45-difluorobenzonitrile / 100mg / 600833270 / A195578 / / 1349715-72-5 / MFCD20233294 / 218.001 / C7H2BrF2N
![Medchemexpress LLC N-(3,3-dimethylbutyl)-N'-(2-fluoro-4-methyl-5-(pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea | 1454682-72-4 | MFCD28411374 | >98.0% | 424.52 | C23H29FN6O | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00132390-MCE-LOGO.JPG-250.jpg){kind=logo}
Medchemexpress LLC N-(3,3-dimethylbutyl)-N'-(2-fluoro-4-methyl-5-(pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea | 1454682-72-4 | MFCD28411374 | >98.0% | 424.52 | C23H29FN6O | 50MG
LY3009120 (DP-4978) is an investigational small-molecule pan-RAF kinase inhibitor developed by Eli Lilly. It inhibits A-RAF, B-RAF (including BRAFV600E), and C-RAF, interferes with RAF dimer signaling, and has demonstrated low-nanomolar biochemical potency and antitumor activity in preclinical models and early clinical studies.
- Pan-RAF inhibition including BRAFV600E, BRAFWT, and CRAFWT
- Low-nanomolar biochemical potency (reported IC50s: 5.8 nM, 9.1 nM, 15 nM)
- Activity in BRAF- or RAS-mutant preclinical cancer models
- Suitable for mechanistic and pharmacology research
- High purity material suitable for biological assays
![Medchemexpress LLC 1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea | 1454682-72-4 | MFCD28411374 | 98.7% | 424.51 g/mol | C23H29FN6O | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237992.png-250.jpg)
Medchemexpress LLC 1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea | 1454682-72-4 | MFCD28411374 | 98.7% | 424.51 g/mol | C23H29FN6O | 25MG
LY3009120 (DP-4978) is a potent pan-RAF kinase inhibitor active against ARAF, BRAF (including V600E), and CRAF. It inhibits downstream MEK and ERK phosphorylation, shows antiproliferative effects in BRAF- and KRAS-mutant cell lines, and has demonstrated tumor regression in preclinical xenograft models. Supplied as a high-purity research compound with defined storage recommendations for powder and solvent formats.
- Pan-RAF activity with low-nanomolar potency against BRAF V600E, BRAF wild-type, and CRAF.
- Inhibits MEK and ERK phosphorylation downstream of RAF.
- Antiproliferative in BRAF- and KRAS-mutant cell lines.
- Produces tumor regression in preclinical xenograft models.
- High purity and defined storage recommendations for powder and solvent preparations.
Sigma Aldrich 5-(4-Fluorophenyl)-1,3-cyclohexanedione
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Frontier Specialty Chemicals 5G 2-CHLORO-4-FLUOROPHENYLBORO
This item has a minimum qty of 5 per supplier requirements.
2-Chloro-4-fluorophenylboronic acid; CAS No: 313545-72-1
Medchemexpress LLC CDK9-IN-2 | 1263369-28-3 | 98.7% | 425.93 | 5 MG
CDK9-IN-2 is a special cyclin-dependent kinase 9 (CDK9) inhibitor, extracted from patent WO/2012131594A1, compound CDKI(8). It has an IC50 of 5 nM and 7 nM in H929 multiple myeloma (MM) cell line (72 hours) and A2058 skin cell line (72 hours), respectively. It is for research use only and not sold to patients.
- Special cyclin-dependent kinase 9 (CDK9) inhibitor.
- Extracted from patent WO/2012131594A1, compound CDKI(8).
- IC50 of 5 nM in H929 multiple myeloma (MM) cell line (72 hours).
- IC50 of 7 nM in A2058 skin cell line (72 hours).
- Reduces expression of MEPCE.
- Reduces MCL1 protein expression.
- Appearance: solid, light yellow to yellow.
- Effective in inhibiting CDK9 activity.
- Has antiproliferative activity against various cell lines including 4T1, A498, A549, AD293, BT-549, HK-2, HeLa, HepG2, Hs-578T, L02, MCF-10A, MDA-MB-231, and MRC5.
1-Bromo-3-chloro-5-fluorobenzene, 98%, Thermo Scientific™
CAS: 33863-76-2 Molecular Formula: C6H3BrClF Molecular Weight (g/mol): 209.45 InChI Key: GGMDFPMASIXEIR-UHFFFAOYSA-N Synonym: 3-chloro-5-fluorobromobenzene,1-bromo3-chloro-5-fluorobenzene,1-bromo-3-chloro-5-fluoro-benzene,benzene, 1-bromo-3-chloro-5-fluoro,1,3,5-fluorochlorobromobenzene,pubchem2261,acmc-209i3i,ksc494q7t,3-chloro-5-fluoro-bromobenzene,1-bromo-3-chloro-5-flurobenzene PubChem CID: 2736223 IUPAC Name: 1-bromo-3-chloro-5-fluorobenzene SMILES: C1=C(C=C(C=C1Cl)Br)F