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Oritinib is an irreversible, third-generation EGFR tyrosine kinase inhibitor developed to overcome T790M-mediated resistance. Supplied as a high-purity solid research compound, it is used in preclinical biochemical and cellular studies to interrogate EGFR signaling and resistance mechanisms.
Irreversible third-generation EGFR inhibitor.
Active against T790M resistance mutations.
High chemical purity (99.6%).
Provided as a solid suitable for dosing and formulation.
Applicable to biochemical and cellular assays.
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Medchemexpress, HY-112125A 5mg KRN2 (bromide) CAS:1390654-28-0 KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Siramesine (Lu 28-179) is a sigma receptor agonist selective for the 2 subtype with IC50 values of 0 12 nM and 17 nM for 2 and 1 receptors respectively
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Medchemexpress, HY-32015 5mg Cot inhibitor-1 CAS:915365-57-0 Cot inhibitor-1 (compound 28) is a selective tumor progression loci-2 (Tpl2) kinase inhibitor with an IC50 of 28 nM. Cot inhibitor-1 shows an inhibition of TNF-alpha production in human whole blood with an IC50 of 5.7 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More