Iodobenzenes
Medchemexpress LLC 2-Cyclopentyl-4-(7-((10-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl) carb... | 2922675-91-8 | 98.2% | 917.17 | 25 MG
CC-3240 is a molecular glue degrader of CaMKK2 with an IC50 of 9 nM. It demonstrates antiproliferative activity against human A-427 cells.
- Molecular glue degrader of CaMKK2.
- IC50 of 9 nM.
- Antiproliferative activity against human A-427 cells.
Medchemexpress LLC CC-3240 | 2922675-91-8 | 98.2% | 917.17 | 5 MG
CC-3240 is a molecular glue degrader of CaMKK2, based on compound 13, with an IC50 of 9 nM. It is intended for research use only and is not for patient treatment.
- Antiproliferative activity against human A-427 cells.
- Reduction in cell growth after 48 hours incubation by CellTiter assay (EC50 > 8 μM).
Medchemexpress LLC Amiodarone hydrochloride | 19774-82-4 | C25H30ClI2NO3 | 500 MG
Amiodarone hydrochloride is a benzofuran-based Class III antiarrhythmic agent. It has been shown to inhibit WT outward IhERG tails and induce cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling in fibroblasts. It is suitable for research into both supraventricular and ventricular arrhythmias.
- Benzofuran-based Class III antiarrhythmic agent
- Inhibits WT outward IhERG tails with an IC50 of approximately 45 nM
- Induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling
- Useful in research for supraventricular and ventricular arrhythmias
Medchemexpress LLC CC-3240 | 2922675-91-8 | 98.23% | 917.17 | 1 MG
CC-3240 (compound 13) is a molecular glue degrader of CaMKK2 based on CC-8977, with an IC50 of 9 nM. It is for research use only and not sold to patients.
- Molecular glue degrader of CaMKK2
- IC50 of 9 nM
- Antiproliferative activity against human A-427 cells (EC50 > 8 μM)
Medchemexpress LLC Isovanillic acid | 645-08-9 | 5 MG
Isovanillic acid (3-Hydroxy-4-methoxybenzoic acid) is a phenolic acid isolated from *Scrophularia ningpoensis*. It exhibits anti-thrombotic activity and is involved in various biological processes.
- Increases 2-[14C(U)]-deoxy-D-glucose (2-DG) uptake in LHCN-M2 cells, which has potential in research of insulin resistance and type 2 diabetes
- Exhibits uncompetitive inhibitory activity against thrombin
- Inhibits the formation of fibrin clot and blood clot
- Prolongs partial thromboplastin time
- Increases platelet aggregation closure time, showing antithrombotic, anticoagulant, and antiplatelet activities