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Filtered Search Results
eMolecules 2169223-49-6 | Medchem Express | JAB-3068 (hydrochloride) | 5mg | 603242350 | HY-131132A | 513 | C22H27ClF2N6O2S
Medchem Express | MK-0493 | 5mg | 716994058 | HY-118930 | 455956-93-1 | 546.100 | C30H38ClF2N3O2
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Medchemexpress LLC 3-[(2,7-dimethoxyacridin-9-yl)sulfanyl]propan-1-amine | 184582-62-5 | MFCD02752814 | 99.6% | C18H20N2O2S | 10MG
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LDN-192960 is a small-molecule research inhibitor selective for Haspin kinase and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2), exhibiting low-nanomolar potency in enzymatic assays. It is provided for laboratory research as a high-purity solid or as a 10 mM solution in DMSO and is used in studies of cell-cycle regulation and kinase signaling.
- Potent inhibition of Haspin (IC50 ≈ 10 nM) and DYRK2 (IC50 ≈ 48 nM).
- High reported purity (≈99.6%).
- Available as solid quantities and as a 10 mM DMSO solution for assay use.
- Molecular formula C18H20N2O2S; molecular weight ≈328.43 g/mol.
- Intended for laboratory research use only; not for human or clinical use.
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Medchemexpress LLC EAAT2 activator 1 | 892415-28-0 | 98.9% | 331.80 | 50 MG
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EAAT2 activator 1 is a potent activator of excitatory amino acid transporter 2 (EAAT2). EAAT2 is the primary glutamate transporter responsible for removing glutamate from synapses. This activator increases EAAT2 protein levels in a dose-dependent manner.
- Potent activator of EAAT2
- Removes glutamate from synapses
- Increases protein levels dose-dependently
- Solid appearance
- Light brown to brown color
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Medchemexpress LLC HY-114403 10mg Medchemexpress, VU6012962 CAS: Purity:>98%
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Medchemexpress, HY-114403 10mg VU6012962 CAS: VU6012962 is an orally bioavailable and CNS-penetrant metabotropic glutamate receptor 7 negative allosteric modulator (mGlu7 NAM) with an IC50 of 347 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Phenoxybenzamine hydrochloride | 63-92-3 | 99.5% | 25 MG
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Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist commonly used for hypertension research, particularly for pheochromocytoma. It also demonstrates antitumor activity.
- Inhibits U251 and U87MG cell proliferation.
- Inhibits migration and invasion of U251 and U87MG cells.
- Activates LINGO-1 and inhibits the TrkB-Akt pathway.
- Prevents hippocampal cell death after oxygen glucose deprivation.
- Shows anti-tumorigenic effect in nude mice with U87MG tumors.
- Neuroprotective in a rat model of severe traumatic brain injury.
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Accela Chembio Inc 4-(trifluoromethoxy)benzoic Acid | 100g | 330-12-1 | MFCD00002541 | 97+% | Shelf Life: 1260 Days | Regular
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4-(trifluoromethoxy)benzoic Acid | 100g | 330-12-1 | MFCD00002541 | 97+% | Shelf Life: 1260 Days | Regular
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Accela Chembio Inc 4-(difluoromethoxy)aniline | 100g | 22236-10-8 | MFCD00085005 | 98% | D: 1.283 | Shelf Life: 1080 Days | Light Sensitive/n2/+4
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4-(difluoromethoxy)aniline | 100g | 22236-10-8 | MFCD00085005 | 98% | D: 1.283 | Shelf Life: 1080 Days | Light Sensitive/n2/+4
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Medchemexpress LLC N-((1R,3S)-3-(4-acetylpiperazin-1-yl)cyclohexyl)-7-fluoro-4-methyl-1H-indole-2-carboxamide | 2411748-50-8 | 99.1% | C22H29FN4O2 | 10MG
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EZM0414 is a selective, orally bioavailable small-molecule inhibitor of the histone methyltransferase SETD2, developed for preclinical research applications. It exhibits potent biochemical and cellular activity and is intended for laboratory research into SETD2-driven biology and oncology models.
- Selective SETD2 inhibitor with biochemical IC50 ~18 nM.
- Demonstrates cellular activity (IC50 ~34 nM).
- Orally bioavailable in preclinical models.
- High purity (≈99%) suitable for biochemical and cellular assays.
- Applicable to research on hematologic and solid tumor models.
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Medchemexpress LLC Emvododstat (PTC299) | 1256565-36-2 | 99.9% | 467.34 g/mol | C25H20Cl2N2O3 | 50MG
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PTC299 (emvododstat) is an orally active small-molecule inhibitor that selectively suppresses VEGFA mRNA translation and inhibits dihydroorotate dehydrogenase (DHODH). Provided for research use, it is supplied as solid samples and DMSO solutions and is used in studies of VEGF regulation, pyrimidine biosynthesis, and oncology and immunology research.
- High purity: 99.9% by assay.
- Molecular weight: 467.34 g/mol.
- Chemical formula: C25H20Cl2N2O3.
- Physical appearance: white to light yellow solid.
- Available as solid and as 10 mM solution in DMSO.
- Suitable for studies of VEGF regulation and DHODH-related pathways.
- Offered in multiple package sizes including 50 mg.
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eMolecules 58879-34-8 | (S)-(5-Oxotetrahydrofuran-2-yl)methyl 4-methylbenzenesulfonate | Oakwood Chemical | MFCD00082548 | 270.300 | C12H14O5S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OC[C@@H]1CCC(=O)O1 | 100mg | 537714944
(S)-(5-Oxotetrahydrofuran-2-yl)methyl 4-methylbenzenesulfonate | Oakwood Chemical | 58879-34-8 | MFCD00082548 | 270.300 | C12H14O5S | 98.000 | Cc1ccc(cc1)S(=O)(=O)OC[C@@H]1CCC(=O)O1 | 100mg | 537714944
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Medchemexpress LLC SRC INHIBITOR 1 5MG
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Src Inhibitor 1 is a potent, ATP-competitive and selective dual site Src tyrosine kinase inhibitor with IC50 values of 44 nM for Src and 88nM for Lck.CAS No. : 179248-59-0
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Medchemexpress LLC Gallopamil hydrochloride | 16662-46-7 | MFCD00867067 | 99.2% | C28H41ClN2O5 | 10MG
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Gallopamil hydrochloride is the hydrochloride salt of gallopamil, a methoxy derivative of verapamil and an L-type calcium channel blocker. It is supplied as a white to off-white solid and as a ready-to-use DMSO solution for in vitro research into calcium channel function and cardiovascular pharmacology.
- Potent L-type calcium channel blocker for pharmacology studies.
- Available as solid and 10 mM solution in DMSO for convenient dosing.
- High purity suitable for biochemical and cellular assays.
- Characterized by verified CAS, formula, and molecular weight for reproducibility.
- Provided with datasheet and certificate of analysis for traceability.
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Medchemexpress LLC BMS-191095 | 166095-21-2 | 98.0% | C22H21ClN4O2 | 100 MG
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BMS-191095 is a selective activator of mitochondrial ATP-sensitive potassium (mitoKATP) channels, inhibiting human platelet aggregation by opening mitochondrial K(ATP) channels. It induces mitochondrial depolarization of vascular smooth muscle (VSM) cells and dose-dependently induces vasodilation in endothelium-denuded cerebral arteries. BMS-191095 also reduces neuronal damage in rats with transient focal cerebral ischemia.
- Induces mitochondrial depolarization of vascular smooth muscle (VSM) cells.
- Dose-dependently induces vasodilation in endothelium denuded cerebral arteries.
- Increases the frequency of calcium sparks in VSM cells.
- Inhibits human platelet aggregation induced by collagen and thrombin.
- Reduces neuronal damage in rats with transient focal cerebral ischemia.
- Reduces total infarct volume and induces rapid mitochondrial depolarization in rats with ischemia.
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Medchemexpress LLC Propoxycaine hydrochloride | 550-83-4 | MFCD01660627 | 99.7% | 330.85 | C16H27ClN2O3 | 10 MG
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Propoxycaine hydrochloride is an ester-type local anesthetic and sodium-channel inhibitor supplied as a solid research reagent. It is used in laboratory studies requiring blockade of voltage-gated sodium channels and is provided with documentation for purity and storage.
- Inhibits voltage-gated sodium channels, reducing nerve impulse conduction.
- Supplied as a white to light brown solid suitable for in vitro use.
- Molecular formula C16H27ClN2O3 and molecular weight 330.85 g/mol.
- High purity (≈99.7-99.98%) with available certificate of analysis.
- Storage recommendations: 4°C sealed for solid; in solvent -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC 3-piperidinecarboxamide, 1-[3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl) | 1207113-88-9 | 99.3% | 100 MG
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CCG-100602 is a small-molecule inhibitor that selectively blocks myocardin-related transcription factor A (MRTF-A) / serum response factor (SRF) signaling by preventing MRTF-A nuclear localization; supplied as a white to off-white solid for research use.
- Selective MRTF-A/SRF pathway inhibitor.
- CAS 1207113-88-9.
- Molecular weight 478.82 g/mol.
- Purity 99.29% (LCMS).
- Available as solid (5-500 mg) and as 10 mM DMSO solutions.
- Store solid at 4°C; in solvent store at -80°C for long-term.
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