Phenoxy compounds

Organic compounds that have one or more phenyl groups that are bonded to an oxygen with a radical electron; includes compounds with additional substitutions.

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2,431 – 2,445 of 2,725 results

2,431

eMolecules 59674-85-0 | 7-Aminoquinazoline-2,4(1H,3H)-dione | MFCD13191696 | 100mg

Ambeed | 7-Aminoquinazoline-2,4(1H,3H)-dione | 100mg | 506391219 | A532977 | 59674-85-0 | MFCD13191696 | 177.163 | C8H7N3O2

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2,432

Medchemexpress LLC Tucatinib hemiethanolate | 1429755-56-5 | 98.8% | 503.57 | 50 MG

Tucatinib hemiethanolate is a potent, orally active, and selective HER2 inhibitor. It demonstrates nanomolar activity against purified HER2 enzyme and is approximately 500-fold selective for HER2 versus EGFR in cell-based assays. It selectively inhibits the receptor tyrosine kinase HER2 relative to EGFR, blocking proliferation and phosphorylation of HER2 and its downstream effector, Akt in HER2 overexpressing cell lines. It is intended for research use only.

Potent and selective HER2 inhibition (IC50 of 8 nM)
Antiproliferative effects in HER2 overexpressing cell lines
Reduced EGFR-related toxicities
Anti-tumor activity and survival benefit in animal models
Significant reduction in brain pErbB2 (80%)
Dose-related tumor growth inhibition
Enhanced tumor growth inhibition when combined with trastuzumab
Studied in various clinical trials

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2,433

Accela Chembio Inc Bis(pentafluorophenyl) Carbonate | 25g | 59483-84-0 | MFCD00368353 | 97+% | Shelf Life: 1440 Days | +4

Bis(pentafluorophenyl) Carbonate | 25g | 59483-84-0 | MFCD00368353 | 97+% | Shelf Life: 1440 Days | +4

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2,434

Medchemexpress LLC Tucatinib hemiethanolate | 1429755-56-5 | 98.8% | 503.57 | 100 MG

Tucatinib hemiethanolate is a potent, orally active, and selective HER2 inhibitor. With an IC50 of 8 nM, it selectively targets HER2, showing approximately 500-fold selectivity over EGFR in cell-based assays. This compound is intended for research use only.

Potent, orally active, and selective HER2 inhibitor
Selectively inhibits receptor tyrosine kinase HER2 relative to EGFR
Blocks proliferation and phosphorylation of HER2 and its downstream effector Akt
Demonstrated anti-tumor activity and improved survival in animal models

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2,435

eMolecules 131179-95-8 | Medchem Express | Efaproxiral | 50mg | 446263211 | HY-13619 | MFCD00899086 | 341.407 | C20H23NO4

Ambeed | Benzyl 5-aminopentanoate hydrochloride | 5g | 572859746 | A1037243 | 154407-91-7 | MFCD25371665 | 243.730 | C12H18ClNO2

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2,436

Medchemexpress LLC AMTB hydrochloride | 926023-82-7 | 99.2% | 430.99 | C23H27ClN2O2S | 5 MG

AMTB hydrochloride is a research-grade small molecule that selectively blocks TRPM8 ion channels and also inhibits voltage-gated sodium channels. Supplied as a white to off-white solid with high chemical purity, it is intended for in-vitro and in-vivo research applications investigating TRPM8-mediated physiology and pharmacology.

Selective TRPM8 channel blocker and non-selective voltage-gated sodium channel inhibitor.
High purity: 99.18%.
White to off-white solid form suitable for formulation.
Soluble in DMSO (up to 100 mg/mL) with sonication.
In vivo formulation protocols available for concentrations ≥ 2.5 mg/mL.
Supplied in small research pack sizes, including 5 mg.

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2,437

eMolecules 63019-39-6 | 3-Hydroxychrysene | Toronto Research Chemicals | MFCD01736446 | 244.293 | C18H12OOc1ccc2ccc3c4ccccc4ccc3c2c1 | 100mg | 483412499

3-Hydroxychrysene | Toronto Research Chemicals | 63019-39-6 | MFCD01736446 | 244.293 | C18H12OOc1ccc2ccc3c4ccccc4ccc3c2c1 | 100mg | 483412499

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2,438

Medchemexpress LLC PARP14 inhibitor H10 | 2084811-68-5 | 99.5% | 557.58 | C24H27N7O7S | 10 MG

A selective small-molecule inhibitor of PARP14 designed for biochemical and cellular research targeting PARP14-mediated pathways and apoptosis.

Selective PARP14 inhibitor with reported IC50 of 490 nM.
High reported purity (99.46% as supplied).
Molecular weight 557.58 and formula C24H27N7O7S.
Supplied as a solid (off-white to yellow) or as a 10 mM solution in DMSO for easy reconstitution.
Available in small research quantities, including 10 mg.

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2,439

Medchemexpress LLC 1,4-dimethoxybenzene | 150-78-7 | MFCD00008401 | 100.0% | 138.16 g/mol | C8H10O2 | 50 MG

Analytical reference standard of 1,4-dimethoxybenzene (CAS 150-78-7) supplied as a high-purity crystalline solid for research and analytical applications. It is intended for instrument calibration, method development, and quality control where a well-characterized reference compound is required.

High purity (99.99%) for analytical reliability.
Molecular formula C8H10O2, molecular weight 138.16 g/mol.
White to colorless crystalline solid with melting point ~55-60 °C.
Suitable for calibration, method development, and quality control.
Provided in small, measured quantities for laboratory use.

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2,440

Medchemexpress LLC KRAS G12C inhibitor 15 | 2349393-21-9 | 98.5% | 498.91 g/mol | C25H21ClF2N4O3 | 100MG

KRAS G12C inhibitor 15 is a research-grade small-molecule inhibitor selective for the KRAS G12C mutant, derived from patent WO2019110751A1 (compound 22). It is reported to inhibit KRAS G12C with an IC50 of 5 nM and is supplied as a solid for laboratory research use only.

Potent KRAS G12C inhibition (IC50 5 nM).
High purity (~98.5%).
Molecular weight 498.91 g/mol; formula C25H21ClF2N4O3.
White to yellow solid suitable for biochemical and cellular assays.
Supplied as 100 MG for research use only.
Derived from patent WO2019110751A1 (compound 22).

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2,441

Selleck Chemical LLC Schisandrin B S3600-10mg

Schisandrin B is the most abundant dibenzocyclooctadiene lignan present in the traditional Chinese medicinal herb Schisandra chinensis (Turcz ) Baill It is a kind of ATR and P-gp inhibitor with high safety

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2,442

Selleck Chemical LLC LY2109761 S2704-200mg

LY2109761 is a novel selective TGF- receptor type I/II (T RI/II) dual inhibitor with Ki of 38 nM and 300 nM in a cell-free assay respectively shown to negatively affect the phosphorylation of Smad2 LY2109761 blocks autophagy and induces apoptosis

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2,443

eMolecules 101526-62-9 | Medchem Express | Sematilide (hydrochloride) | 5mg | 713704199 | HY-101436A | MFCD01667315 | 349.87 | C14H24ClN3O3S

Pharmablock | methyl 2-bromo-13-benzothiazole-6-carboxylate | 25mg | 784547251 | PBT8584 | 1024583-33-2 | MFCD16660646 | 272.120 | C9H6BrNO2S

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2,444

eMolecules 947914-18-3 | Medchem Express | ML365 | 5mg | 446261098 | HY-12345 | MFCD09204310 | 360.413 | C22H20N2O3

Medchem Express | ML365 | 5mg | 446261098 | HY-12345 | 947914-18-3 | MFCD09204310 | 360.413 | C22H20N2O3

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2,445

Medchemexpress LLC DSM705 hydrochloride | 2989908-08-7 | 99.6% | C19H20ClF3N6O | 10MG

DSM705 hydrochloride is the hydrochloride salt of DSM705, a pyrrole-based dihydroorotate dehydrogenase (DHODH) inhibitor with oral antimalarial activity. It shows nanomolar potency against Plasmodium DHODH (IC50 ≈95 nM for P. falciparum and ≈52 nM for P. vivax) and activity against Plasmodium parasites, with minimal inhibition of mammalian DHODHs.

Pyrrole-based DHODH inhibitor with nanomolar potency.
Orally active antimalarial compound.
Selective for Plasmodium DHODH over mammalian DHODHs.
Hydrochloride salt form for improved solubility and handling.
Available in multiple solid and solution pack sizes for research use.
Reported purity approximately 99.6%.

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Phenoxy compounds

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Medchemexpress LLC Tucatinib hemiethanolate | 1429755-56-5 | 98.8% | 503.57 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Accela Chembio Inc Bis(pentafluorophenyl) Carbonate | 25g | 59483-84-0 | MFCD00368353 | 97+% | Shelf Life: 1440 Days | +4 Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tucatinib hemiethanolate | 1429755-56-5 | 98.8% | 503.57 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AMTB hydrochloride | 926023-82-7 | 99.2% | 430.99 | C23H27ClN2O2S | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PARP14 inhibitor H10 | 2084811-68-5 | 99.5% | 557.58 | C24H27N7O7S | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1,4-dimethoxybenzene | 150-78-7 | MFCD00008401 | 100.0% | 138.16 g/mol | C8H10O2 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC KRAS G12C inhibitor 15 | 2349393-21-9 | 98.5% | 498.91 g/mol | C25H21ClF2N4O3 | 100MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DSM705 hydrochloride | 2989908-08-7 | 99.6% | C19H20ClF3N6O | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More