Phenoxy compounds

Medchemexpress LLC HY-112607 5mg Medchemexpress, Tubulin inhibitor 1 CAS:2237054-53-2 Purity:>98%

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Medchemexpress, HY-112607 5mg Tubulin inhibitor 1 CAS:2237054-53-2 Tubulin inhibitor 1 is a tubulin inhibitor, inhibits tubulin polymerization. Tubulin inhibitor 1 shows potent anti-tumor activity, casues cellular mitotic arrest in the G2/M phase, and induces cellular apoptosis [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Medchemexpress LLC HY-112607 10mg Medchemexpress, Tubulin inhibitor 1 CAS:2237054-53-2 Purity:>98%

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Medchemexpress, HY-112607 10mg Tubulin inhibitor 1 CAS:2237054-53-2 Tubulin inhibitor 1 is a tubulin inhibitor, inhibits tubulin polymerization. Tubulin inhibitor 1 shows potent anti-tumor activity, casues cellular mitotic arrest in the G2/M phase, and induces cellular apoptosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

eMolecules​ Medchem Express / Tubulin inhibitor 1 / 5mg / 459606846 / HY-112607 / / 2237054-53-2 / [null] / 368.433 / C21H24N2O4

Medchem Express / Tubulin inhibitor 1 / 5mg / 459606846 / HY-112607 / / 2237054-53-2 / [null] / 368.433 / C21H24N2O4

Medchemexpress LLC HY-13968 10mg Medchemexpress, JW 55 CAS:664993-53-7 Purity:>98%

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Medchemexpress, HY-13968 10mg JW 55 CAS:664993-53-7 JW 55 is a potent and selective β-catenin signaling pathway inhibitor, which functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2). JW 55 decreases auto-PARsylation of TNKS1/2 in vitro with IC50s of 1.9 μM and 830 nM respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Apexbio Technology LLC JW 55 664993-53-7 10mg

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JW 55 (CAS 664993-53-7) is a small-molecule inhibitor that targets the poly(ADP-ribose) polymerase (PARP) domains of tankyrase 1 and tankyrase 2 (TNKS1/2) with reported IC50 values of 1 9 M and 0 83 M respectively By inhibiting TNKS1/2 activity JW 55 stabilizes AXIN2 a component of the -catenin destruction complex leading to enhanced degradation of -catenin and suppression of canonical Wnt/ -catenin signaling In vitro JW 55 suppresses Wnt pathway activity in colorectal cancer cells harboring APC or -catenin mutations In vivo it reduces Wnt-driven phenotypes in Xenopus embryos and diminishes polyp formation in APC-mutant mice supporting its utility as a research tool in Wnt/ -catenin signaling and cancer biology