Phenoxy compounds
4-(Hexyloxy)benzoic Acid 98.0+%, TCI America™
CAS: 1142-39-8 Molecular Formula: C13H18O3 Molecular Weight (g/mol): 222.284 MDL Number: MFCD00013991 InChI Key: HBQUXMZZODHFMJ-UHFFFAOYSA-N PubChem CID: 70834 IUPAC Name: 4-hexoxybenzoic acid SMILES: CCCCCCOC1=CC=C(C=C1)C(=O)O
eMolecules RVX-208 | 1044870-39-4 | | 50mg
Broadpharm | RVX-208 | 50mg | 573896523 | BP-23380 | 98.000 | 1044870-39-4 | | 370.405 | C20H22N2O5
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Medchemexpress LLC Apabetalone | 1044870-39-4 | 99.34% | 370.40 | 100 MG
Apabetalone (RVX-208) is an inhibitor of BET transcriptional regulators, specifically targeting the second bromodomain (BD2) with high selectivity. It enhances the production of ApoA-I in hepatocytes, leading to an increase in high-density lipoprotein cholesterol (HDL-C). Its mechanism involves binding to bromodomains of the BET family by competing for acetylated lysine binding sites. This epigenetic modulation of ApoA-I production suggests it as a potential therapeutic agent for atherosclerosis.
- Selective BET transcriptional regulator inhibitor
- Targets the second bromodomain (BD2)
- Increases ApoA-I production in liver cells
- Elevates high-density lipoprotein cholesterol (HDL-C)
- Acts via an epigenetic mechanism
- Investigated for atherosclerosis treatment
Medchemexpress LLC HY-16652 50mg , RVX-208 Apabetalone;RVX000222 CAS:1044870-39-4 Purity:98%
Medchemexpress, HY-16652 50mg RVX-208 Apabetalone;RVX000222 CAS:1044870-39-4 Formula:C20H22N2O5 IC50: 510±41 nM (BD2), 87±10 μM (BD1) Purity:98% RVX-208 is an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain. The IC 50 s are 87±10 μM and 0.51±0.041 μM for BD1 and BD2 , respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Methanone, (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl) | 105925-39-1 | MFCD01245092 | 99.0% | 367.85 g/mol | C20H14ClNO2S | 5 MG
Tubulin inhibitor 6 (CAS 105925-39-1) is a small-molecule research compound used to probe microtubule dynamics and anti-mitotic mechanisms in vitro. It inhibits tubulin polymerization and demonstrates cytotoxic activity in cell-based assays, supplied in small milligram quantities for laboratory research.
- Inhibits tubulin polymerization with an IC50 of 0.87 μM.
- Inhibits K562 cell growth with an IC50 of 840 nM.
- High stated purity (~99%) appropriate for biochemical and cellular assays.
- Molecular weight 367.85 g/mol; molecular formula C20H14ClNO2S.
- Provided in milligram-scale quantities for research use.
![Medchemexpress LLC 3,5-dimethoxybenzoic acid 2-[(1-naphthalenylamino)carbonyl]hydrazide | 444932-31-4 | MFCD02372953 | ≥98.0% | 365.38 g·mol⁻¹ | C20H19N3O4 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000245685.png-250.jpg)
Medchemexpress LLC 3,5-dimethoxybenzoic acid 2-[(1-naphthalenylamino)carbonyl]hydrazide | 444932-31-4 | MFCD02372953 | ≥98.0% | 365.38 g·mol⁻¹ | C20H19N3O4 | 50 MG
TC-O 9311 is a potent, selective agonist of the orphan G protein-coupled receptor GPR139 used as a research tool in cell-based pharmacology. It was disclosed as Compound 1a in the primary literature and shows an EC50 of 39 nM in CHO-K1 cells expressing human GPR139. The compound is characterized for in vitro use and is typically supplied at high purity for pharmacological studies.
- Potent GPR139 agonist (EC50 = 39 nM in CHO-K1 cells).
- High selectivity with no cross-reactivity across a diverse 90-target panel.
- Suitable as a positive control in cell-based pharmacology assays.
- Supplied at high purity (≥98% by HPLC).
- Well characterized: CAS 444932-31-4; MFCD02372953; formula C20H19N3O4; MW 365.38 g·mol⁻¹.