Phenylcarbamic acid esters

Medchemexpress LLC Propanoic acid, 3-[2-(2-bromoethoxy)ethoxy]-, 1,1-dimethylethyl ester | 1381861-91-1 | 97.0% | C11H21BrO4 | 1 G

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Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are compounds that exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, featuring two different ligands connected by a linker.

• PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Exploits the intracellular ubiquitin-proteasome system
• Selectively degrades target proteins
• Colorless to light yellow liquid appearance
• Purity of 97.0%

Medchemexpress LLC Propanoic acid, 3-[2-(2-bromoethoxy)ethoxy]-, 1,1-dimethylethyl ester | 1381861-91-1 | 97.0% | C11H21BrO4 | 25 G

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Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. This compound is suitable for research applications requiring targeted protein degradation.

• PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• PROTACs contain two different ligands connected by a linker
• Ligands for an E3 ubiquitin ligase and a target protein
• Exploits the intracellular ubiquitin-proteasome system
• Selectively degrades target proteins

Medchemexpress LLC 3-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]propanoic acid | 1365655-91-9 | MFCD22056304 | 98.0% | 277.31 | C12H23NO6 | 5 G

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Boc-NH-PEG2-CH2CH2COOH is a Boc-protected PEG2 linker containing a terminal carboxylic acid and a protected amine. It is designed as a short, two-unit PEG spacer for use in the synthesis of PROTACs and bifunctional conjugates, supplied for research use with documented solubility and storage recommendations.

• Boc-protected amino group for orthogonal deprotection
• Two-unit PEG spacer to improve solubility and linker flexibility
• Terminal carboxylic acid for amide or ester coupling reactions
• Molecular weight 277.31 and formula C12H23NO6
• High solubility in DMSO (≥100 mg/mL) and formulatable in several vehicles
• Storage stability: long-term at -20°C; shorter stability in solution
• For research use only; not validated for medical applications

Medchemexpress LLC 3-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]propanoic acid | 1365655-91-9 | MFCD22056304 | 98.0% | 277.31 g·mol⁻¹ | C12H23NO6 | 10 G

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Boc-NH-PEG2-CH2CH2COOH is a Boc-protected, amino-terminated PEG2 linker with a terminal carboxylic acid. It is intended for use as a short polyethylene glycol spacer in PROTAC synthesis and bioconjugation workflows, providing improved solubility and flexible connection between functional modules. Supplied with batch-specific quality documentation for reproducible synthesis outcomes.

• Boc-protected amino-terminated PEG2 linker suitable for conjugation chemistry.
• Short PEG spacer improves solubility and reduces steric hindrance.
• Terminal carboxylic acid enables amide or ester coupling.
• High purity (≥98%) with batch-specific certificate of analysis.
• Available in multiple pack sizes, including 10 g for synthesis scale-up.