CM-579 trihydrochloride is a reversible, dual inhibitor of histone methyltransferase G9a and DNA methyltransferases (DNMT) with low-nanomolar biochemical potency and demonstrated cellular activity. The compound is provided as a concentrated solution for in vitro studies and is used primarily in epigenetic and cancer research.
- Dual G9a and DNMT inhibition with IC50 ≈ 16 nM (G9a) and 32 nM (DNMT).
- Supplied as a 10 mM solution in DMSO (1 mL) and as solid quantities for flexibility.
- Molecular weight 602.04 and CAS 2448471-08-5 for unambiguous identification.
- Purity typically 97.0% by supplier specification.
- Suitable for epigenetic modulation, target validation, and cancer cell studies.