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Sulfanilides

Organic compounds that contain a sulfonanilide group; this functional group is a type of sulfonamide consisting of a sulfur atom bonded to two oxygen atoms via double bonds, one carbon atom, and one nitrogen atom; they are derivatives of aniline.

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1

Selleck Chemical LLC Dabrafenib Mesylate-25mg

Dabrafenib Mesylate (GSK2118436) is the mesylate salt form of dabrafenib, an orally bioavailable inhibitor of B-raf (BRAF) protein with IC50s of 0.8 nM, 3.2 nM and 5 nM for B-Raf (V600E), B-Raf (WT) and C-Raf, respectively.

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2

Medchemexpress LLC Dpm-1001 | 1471172-27-6 | 99.8% | 5 MG
SDP

DPM-1001 is a small-molecule, orally bioavailable, non-competitive inhibitor of protein-tyrosine phosphatase 1B (PTP1B) with a reported IC50 of approximately 100 nM. It is used in preclinical research to investigate insulin and leptin signaling and metabolic regulation.

  • Non-competitive inhibitor of PTP1B (IC50 ≈ 100 nM).
  • Orally bioavailable in preclinical models.
  • Supports research into insulin and leptin signaling pathways.
  • High reported purity suitable for biochemical assays.
  • Stored cold to maintain stability and activity.

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3

Medchemexpress LLC Litronesib racemate | 546111-97-1 | 99.2% | 511.70 g·mol⁻¹ | C23H37N5O4S2 | 10 MG
SDP

Litronesib racemate is the racemic form of litronesib, a selective, mitosis-specific allosteric inhibitor of the kinesin Eg5 motor protein. It is supplied as a high-purity research reagent with supporting documentation for preclinical studies.

  • High purity (99.2%).
  • Selective mitosis-specific Eg5 inhibitor.
  • Molecular weight 511.70 g·mol⁻¹.
  • Chemical formula C23H37N5O4S2.
  • Available in milligram pack sizes for research use.
  • Includes data sheet, COA, and SDS.
  • For research use only; not for human or veterinary use.

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4

Medchemexpress LLC Dpm-1001 | 1471172-27-6 | 99.8% | 10 MG
SDP

DPM-1001 is a potent, orally active, and non-competitive inhibitor of protein-tyrosine phosphatase 1B (PTP1B) that shows in vitro activity (IC50 ≈ 100 nM) and in vivo efficacy in diet-induced obese mice.

  • Potent PTP1B inhibition with IC50 around 100 nM
  • Orally active and non-competitive mechanism of action
  • Demonstrated efficacy in animal models improving glucose tolerance and reducing body weight
  • High reported purity suitable for research use
  • Available in small pack sizes for preclinical studies

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