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Filtered Search Results
Medchemexpress LLC Benzamide, 4-fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl] ethyl] HCl | 286369-38-8 | 99.9% | 443.94 | 10 MG
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S-14506 hydrochloride is a potent 5-HT1A agonist and a 5-HT2A/2C antagonist. It also demonstrates dopamine antagonist properties by blocking dopamine D2 receptors. This compound effectively inhibits the in vivo binding of [3H]raclopride in the striatum and olfactory bulbs, holding potential for research as an anxiolytic agent.
- Potent 5-HT1A agonist
- 5-HT2A/2C antagonist
- Dopamine D2 receptor blocker
- Inhibits [3H]raclopride binding
- Potential anxiolytic agent
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Medchemexpress LLC Guanine hydrochloride | 635-39-2 | MFCD00213670 | 98.8% | 187.59 g/mol | C5H6ClN5O | 50mg
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Guanine hydrochloride is one of the fundamental components of nucleic acids (DNA and RNA) It is a purine derivative composed of a fused pyrimidine-imidazole ring system with conjugated double bonds Guanine hydrochloride has the potential to serve as a large-capacity nitrogen reservoir[1]
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eMolecules 16292-90-3 | 3-Amino-4-nitrophenol | MFCD13185928 | 1g
ChemScene | 2-Bromo-11-difluorocyclopentane | 100mg | 712788301 | CS-0377806 | 2303705-25-9 | 185.012 | C5H7BrF2
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Medchemexpress LLC MRL-494 hydrochloride | 2699937-04-5 | 98.6% | 1 ML
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MRL-494 hydrochloride is an antibacterial agent that acts as an inhibitor of β-barrel assembly machine A (BamA). It is impervious to efflux and the outer membrane permeability barrier, demonstrating inhibitory effects on both Gram-positive and Gram-negative bacteria. MRL-494 lethally disrupts the cytoplasmic membrane and inhibits outer membrane proteins (OMPs) biogenesis by targeting BamA from outside the outer membrane.
- Acts as an inhibitor of β-barrel assembly machine A (BamA).
- Impervious to efflux and the outer membrane permeability barrier.
- Effective against Gram-positive bacteria, including Staphylococcus aureus COL (MIC of 12.5 μM).
- Effective against Gram-negative bacteria, including E. coli JCM158 (MIC of 25 μM).
- Lethally disrupts the cytoplasmic membrane.
- Inhibits outer membrane proteins (OMPs) biogenesis by targeting BamA.
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Medchemexpress LLC Ozagrel hydrochloride | 78712-43-3 | 99.9% | 5 MG
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Ozagrel hydrochloride is a highly selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. It exerts anti-platelet aggregation, vasodilation, and anti-inflammatory effects by inhibiting TXA2 production and increasing prostacyclin (PGI2) production. This product can be used for the study of ischemic stroke, asthma, and thromboembolic diseases.
- Highly selective and orally active thromboxane A2 (TXA2) synthase inhibitor
- Exerts anti-platelet aggregation, vasodilation, and anti-inflammatory effects
- Inhibits TXA2 production and increases prostacyclin (PGI2) production
- Suitable for research on ischemic stroke, asthma, and thromboembolic diseases
- Purity of 99.86%
- Molecular weight of 264.71
- White to off-white solid appearance
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eMolecules 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 9mg | 564356418
Medetomidine Hydrochloride | Key Organics/BIONET | 86347-15-1236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 9mg | 564356418
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Medchemexpress LLC Biotin-4-aminophenol | 901770-40-9 | 99.45% | C16H21N3O3S | 50 MG
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Biotin-4-aminophenol is a biotin-phenol analog that generates free radicals and conjugates to tyrosine residues in proteins more efficiently and selectively than the previously reported BP1. It is intended for research use only.
- Generates free radicals and conjugates to tyrosine residues in proteins.
- More efficient and selective than previously reported BP1.
- Suitable for spatiotemporal profiling of cytosolic signaling complexes in living cells.
- Can be used with 500 µM working solution for cell incubation.
- Proximity labeling reaction is triggered by H2O2.
- Reaction can be quenched using a specific buffer.
- Supports analysis of digested peptides by nano LC-MS/MS.
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Medchemexpress LLC NS8593 hydrochloride | 875755-24-1 | 99.76% | 299.80 | 1 MG
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NS8593 hydrochloride is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels). It reversibly inhibits SK3-mediated currents with a Kd value of 77 nM. NS8593 hydrochloride inhibits all SK1-3 subtypes in a Ca2+-dependent manner (Kds of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca2+), but does not affect intermediate and large conductance Ca2+-activated K+ channels (hIK and hBK channels, respectively). It is for research use only and not sold to patients.
- Potent and selective small conductance Ca2+-activated K+ channels inhibitor
- Reversibly inhibits SK3-mediated currents with a Kd value of 77 nM
- Inhibits SK1-3 subtypes Ca2+-dependently
- Does not affect intermediate and large conductance Ca2+-activated K+ channels
- Affects firing rate and firing pattern of dopaminergic neurons in vivo in C57Bl/6 mice at doses of 3 and 10 mg/kg intravenously
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eMolecules 86347-15-1 | Medetomidine Hydrochloride | Key Organics/BIONET236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 25mg | 564356421
Medetomidine Hydrochloride | Key Organics/BIONET | 86347-15-1236.740 | C13H17ClN2 | 99.000 | Cl.CC(c1cnc[nH]1)c1cccc(C)c1C | 25mg | 564356421
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Medchemexpress LLC 1-myristoyl-sn-glycero-3-phosphatidylcholine-d7 | 95.4% | 474.62 | 1 MG
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LysoPC(14:0/0:0)-d7 is a deuterium labeled lysophospholipid (LyP). It is a monoglycerophospholipid where a phosphorylcholine moiety occupies a glycerol substitution site. This product exhibits a potent antispasmodic effect and is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Medchemexpress LLC Zymostenol-d7 | 2260669-19-8 | 99.9% | 393.70 | 1 MG
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Zymostenol-d7 is deuterium labeled 5a-Cholest-8-en-3b-ol.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC MRL-494 (hydrochloride) | 2699937-04-5 | 98.6% | 25 MG
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MRL-494 hydrochloride is an antibacterial agent that acts as an inhibitor of β-barrel assembly machine A (BamA). It is impervious to efflux and the outer membrane permeability barrier, effectively inhibiting both Gram-positive and Gram-negative bacteria. The agent lethally disrupts the cytoplasmic membrane and inhibits outer membrane protein biogenesis by targeting BamA.
- Impervious to efflux and outer membrane permeability barrier
- Inhibits both Gram-positive and Gram-negative bacteria
- Lethally disrupts cytoplasmic membrane
- Inhibits outer membrane protein biogenesis
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Medchemexpress LLC BIIL-260 hydrochlori | 100MG
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BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist with anti-inflammatory activity BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable reversible and competitive manner has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1 7 nM[1]
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Medchemexpress LLC ZZW-115 hydrochloride | 10122-45-9 | 98.1% | 573.97 | 1 ML
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ZZW-115 hydrochloride is a potent NUPR1 inhibitor with a Kd of 2.1 μM. It demonstrates anticancer activity by inducing tumor cell death through both necroptosis and apoptosis.
- Potent NUPR1 inhibitor.
- Induces tumor cell death.
- Leads to necroptosis and apoptosis.
- Exhibits anticancer activity.
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Medchemexpress LLC CX-6258 hydrochloride hydrate | 1353858-99-7 | 99.2% | 10 MG
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A research-grade hydrochloride hydrate salt of a potent pan-Pim kinase inhibitor intended for laboratory research use. It selectively inhibits Pim-1, Pim-2, and Pim-3 with reported IC50 values of 5 nM, 25 nM, and 16 nM, respectively. Characterization data and quality documents (SDS, COA, LCMS) are provided by the supplier.
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