Aminophenols
Medchemexpress LLC PF-8380 hydrochloride | 2070015-01-7 | 98.6% | 514.79 g/mol | C22H22ClN2O5S | 5 MG
PF-8380 hydrochloride is a small-molecule autotaxin (ATX) inhibitor supplied as a research reagent. It demonstrates potent inhibition in isolated enzyme assays and measurable activity in human whole blood, and is intended for laboratory research use only.
- Potent autotaxin inhibitor; IC50 2.8 nM in isolated enzyme assay.
- Active in human whole blood with IC50 ~101 nM.
- Molecular weight 514.79 g/mol and formula C22H22ClN2O5S.
- High purity (98.6%), suitable for biochemical and cellular assays.
- Available in small research pack sizes (1 mg, 5 mg, 10 mg).
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC Bepridil hydrochloride | 68099-86-5 | MFCD00065498 | 100.0% | 403.00 g/mol | C24H35ClN2O | 5 MG
Bepridil hydrochloride is the hydrochloride salt of bepridil, a non-selective calcium channel blocker with antianginal activity supplied as a research reagent for in vitro and analytical applications.
- High purity solid (99.98%) suitable for analytical and in vitro research.
- Non-selective calcium channel blocker, useful for cardiovascular and ion-channel studies.
- Available in small analytical pack sizes for assay development and screening.
- Stable when stored sealed and away from moisture; recommended -20°C for long-term storage.
- Also available as a ready-to-use solution (10 mM in DMSO) for assay workflows.
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | MFCD34676707 | 98.2% | 468.98 | C23H29ClN8O | 5 MG
LDC4297 hydrochloride is a small-molecule research reagent that selectively inhibits cyclin-dependent kinase 7 (CDK7). Supplied as the hydrochloride salt for laboratory use only, it is intended for cell-signaling and antiviral research and is available in both solid and solution formats.
- Selective CDK7 inhibition for target-specific studies.
- Suitable for in vitro cell-based assays and mechanistic studies.
- Available in multiple sizes including small solid quantities and DMSO solution.
- High purity suitable for research applications.
- Supplied as the hydrochloride salt for improved stability and solubility.
Medchemexpress LLC Acetaminophen (Standard) | 103-90-2 | 99.97% | C8H9NO2 | 100 MG
Acetaminophen (Standard) is an analytical standard of Acetaminophen, intended for research and analytical applications. Also known as Paracetamol, it acts as a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM, and is widely used as an antipyretic and analgesic agent. It is also a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
- Analytical standard for research and analytical applications.
- Selective cyclooxygenase-2 (COX-2) inhibitor (IC50 of 25.8 μM).
- Widely used antipyretic and analgesic agent.
- Potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.23% | 100 MG
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. This compound demonstrates broad antiviral activities against various viruses, including Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. LDC4297 hydrochloride is suitable for infection research.
- Selective CDK7 inhibitor (IC50: 0.13 nM)
- Inhibits human cytomegalovirus (HCMV) replication (EC50: 24.5 nM)
- Exhibits broad antiviral activities against various viruses (EC50: 0.02-1.21 μM)
- Useful for infection research
Medchemexpress LLC HLCL-61 hydrochloride | 1158279-20-9 | MFCD09446681 | 99.9% | 380.91 g/mol | C23H25ClN2O | 50 MG
HLCL-61 hydrochloride is a first-in-class small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5), provided as a solid research reagent with characterized purity and storage recommendations for biochemical and cellular studies.
- First-in-class PRMT5 inhibitor for research applications.
- High purity suitable for biochemical and cellular assays.
- Supplied as a solid, white to off-white powder.
- Documented molecular formula and molecular weight for experiment planning.
- Storage guidance provided for solvent and dry conditions to preserve stability.
- For research use only; not for human or animal therapeutic use.
Medchemexpress LLC L-742001 hydrochloride | 174605-64-2 | 99.0% | 450.35 | C23H25Cl2NO4 | 5 MG
L-742001 hydrochloride is a research-grade small-molecule inhibitor of influenza virus PA endonuclease, supplied as a high-purity solid for in vitro studies. It reduces vRNP activity in HEK293T cells with an EC90 of 4.3 μM and is intended for laboratory research use only.
- Inhibits influenza PA endonuclease, EC90 of 4.3 μM for vRNP activity in HEK293T cells.
- High purity (99.0%) solid suitable for research applications.
- Molecular weight 450.35 and formula C23H25Cl2NO4.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- For research use only; not for human or veterinary use.
Medchemexpress LLC R 59-022 (hydrochloride) | 93076-98-3 | MFCD34676749 | 98.9% | 496.04 g·mol⁻¹ | C27H27ClFN3OS | 50 MG
R 59-022 hydrochloride is the hydrochloride salt of R 59-022, a research compound that acts as a diacylglycerol kinase (DGK) inhibitor (reported IC50 ≈ 2.8 μM). It is used in cellular and biochemical assays to modulate diacylglycerol/protein kinase C signaling and to probe 5-HT receptor-related pathways. The material is supplied as an off-white solid (CAS 93076-98-3) with formula C27H27ClFN3OS and molecular weight 496.04 g·mol⁻¹.
- DGK inhibitor with reported IC50 ≈ 2.8 μM.
- Modulates protein kinase C and diacylglycerol signaling in cells.
- Hydrochloride salt form for improved handling and solubility in polar solvents.
- High purity suitable for research applications.
- Soluble in DMSO for preparation of stock solutions.
Medchemexpress LLC Prilocaine-d7 hydrochloride | 1786-81-8 | 98.2% | 100 UG
Prilocaine-d7 (hydrochloride) is a deuterium-labeled form of Prilocaine (hydrochloride). Prilocaine hydrochloride is an amino amide and a Na, K-ATPase inhibitor known for its neurotoxic effects. Stable heavy isotopes like deuterium are incorporated into drug molecules primarily as tracers for quantitation during drug development, with potential to affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC ST-836 hydrochloride | 1415564-68-9 | C23H35ClN4OS | 1 ML
ST-836 hydrochloride is a potent dopamine receptor ligand with potential for Parkinson's disease research. It exhibits Ki values of 4.5 nM for D3 and 132 nM for D2 receptors. This compound is provided as a 10 mM solution in dimethyl sulfoxide (DMSO).
- Potent dopamine receptor ligand
- Potential for Parkinson's disease research
- Enhanced water solubility and stability in salt form
Medchemexpress LLC NS8593 (hydrochloride) | 875755-24-1 | 99.8% | 299.80 | 25 MG
NS8593 hydrochloride is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels). It reversibly inhibits SK3-mediated currents with a Kd value of 77 nM. It also inhibits SK1-3 subtypes in a Ca2+-dependent manner (Kds of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca2+), but it does not affect intermediate and large conductance Ca2+-activated K+ channels (hIK and hBK channels).
- Potent and selective small conductance Ca2+-activated K+ channels (SK channels) inhibitor.
- Reversibly inhibits SK3-mediated currents.
- Active on apamin-insensitive SK3 channels.
- Affects firing rate and pattern of dopaminergic neurons in vivo.
Aobchem 2 4-Di-tert-amylphenol | 95% | CAS 120-95-6 | C16H26O | 500g
2 4-Di-tert-amylphenol | 95% | CAS 120-95-6 | C16H26O | 500g
eMolecules 1160861-53-9 | DI-TERT-BUTYL(2',4',6'-TRIISOPROPYL-3,6-DIMETHOXYBIPHENYL-2-YL)PHOSPHINE | AstaTech | MFCD13181930 | 484.705 | C31H49O2P | 97.000 | COc1ccc(OC)c(c1P(C(C)(C)C)C(C)(C)C)-c1c(cc(cc1C(C)C)C(C)C)C(C)C | 5g | 296378213
DI-TERT-BUTYL(2',4',6'-TRIISOPROPYL-3,6-DIMETHOXYBIPHENYL-2-YL)PHOSPHINE | AstaTech | 1160861-53-9 | MFCD13181930 | 484.705 | C31H49O2P | 97.000 | COc1ccc(OC)c(c1P(C(C)(C)C)C(C)(C)C)-c1c(cc(cc1C(C)C)C(C)C)C(C)C | 5g | 296378213
eMolecules 161265-03-8 | Xantphos | Ambeed | MFCD00233866 | 578.632 | C39H32OP2 | 98.000 | CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(cccc12)P(c1ccccc1)c1ccccc1 | 5g | 552589289
Xantphos | Ambeed | 161265-03-8 | MFCD00233866 | 578.632 | C39H32OP2 | 98.000 | CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(cccc12)P(c1ccccc1)c1ccccc1 | 5g | 552589289