Aminophenols
Medchemexpress LLC P-amidinophenylmethylsulfonylfluoride hydrochloride | 74938-88-8 | MFCD00078902 | 95.0% | 252.69 | C8H10ClFN2O2S | 1 MG
p-APMSF hydrochloride is the hydrochloride salt of p-amidinophenylmethylsulfonylfluoride, an irreversible serine protease inhibitor selective for substrates with positively charged side chains such as lysine and arginine. It is provided as a high-purity research reagent for enzymology and biochemical assays.
- Irreversible serine protease inhibitor selective for positively charged side chains.
- Provided as the hydrochloride salt to aid solubility in aqueous assays.
- High purity (95.0%) suitable for research and assay development.
- Molecular weight 252.69; formula C8H10ClFN2O2S.
- Offered in small-scale packaging (1 mg) for screening and mechanistic studies.
Medchemexpress LLC Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 25MG
Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 25MG
Medchemexpress LLC Tecalcet hydrochloride | 177172-49-5 | MFCD16038895 | 99.7% | 340.29 g/mol | C18H23Cl2NO | 1 ML
Tecalcet hydrochloride is an orally active calcimimetic that allosterically and positively modulates the calcium-sensing receptor (CaSR). It is provided for research use in solution and solid forms and is commonly used in in vitro pharmacology and calcium-signaling studies.
- Orally active calcimimetic that modulates the calcium-sensing receptor.
- Suitable for in vitro pharmacology and CaSR signaling studies.
- Available as a 10 mM solution in DMSO (1 mL) and as solid quantities for formulation flexibility.
- High chemical purity (≈99.7%) for reliable experimental results.
- Molecular weight 340.29 g/mol and molecular formula C18H23Cl2NO.
Medchemexpress LLC Nefopam hydrochloride | 23327-57-3 | 99.9% | 1 G
Nefopam hydrochloride is a centrally-acting, non-opioid analgesic drug used for the relief of moderate to severe pain. It targets β-catenin protein levels in mesenchymal cells both in-vitro and in-vivo. This benzoxazocine derivative inhibits β-catenin mediated signaling during skin wound repair.
- Relief of moderate to severe pain.
- Targets β-catenin protein level in mesenchymal cells.
- Non-opioid analgesic.
- Inhibits β-catenin mediated signaling.
Medchemexpress LLC BIIL-260 hydrochlori 10mM 1mL | 192581-24-1 | 1 ML
Biil-260 hydrochloride is a potent leukotriene B4 (LTB4) receptor antagonist used in research to investigate inflammatory signaling pathways. It is typically supplied at high purity and commonly provided as a 10 mM solution in DMSO for in vitro applications.
- Potent LTB4 receptor antagonist
- High purity (99.4%)
- Molecular weight 503.03 g/mol
- Supplied as a 10 mM solution in DMSO, 1 mL
- Appearance: solid, white to off-white
- Storage: solids sealed at 4°C; in solution store at -80°C for long term
Medchemexpress LLC Sotorasib-d7 (AMG-510-d7) | 98.9% | 567.64 g/mol | C30H23D7F2N6O3 | 5 MG
Sotorasib-d7 (AMG-510-d7) is a deuterium-labeled internal standard of sotorasib intended for research and analytical use, suitable as a tracer or internal standard for quantitative NMR, GC-MS, and LC-MS workflows. Supplied as a high-purity solid, it is formulated for reliable analytical performance and stable storage under controlled conditions.
- Deuterium-labeled internal standard suitable for NMR, GC-MS, and LC-MS.
- High purity (98.9%) for consistent analytical results.
- Molecular weight 567.64 g/mol and formula C30H23D7F2N6O3.
- White to light yellow solid for straightforward handling.
- Soluble in DMSO at ≥100 mg/mL for concentrated stock preparation.
- Stable when stored at -20°C under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC PD153035 hydrochloride | 183322-45-4 | 99.5% | 1 ML
PD153035 hydrochloride is a potent ATP-competitive epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor supplied as a ready-to-use DMSO stock solution for biochemical and cell-based research applications.
- Potent EGFR inhibitor with reported Ki = 6 pM and IC50 = 25 pM.
- Supplied as a 10 mM solution in DMSO (1 mL) for convenient dosing in assays.
- High purity suitable for biochemical and cell-based studies.
- CAS number 183322-45-4 for unambiguous identification.
- Molecular weight 396.67 g/mol and formula C16H15BrClN3O2.
- Widely used in kinase signaling and cancer research to block EGFR activity.
Medchemexpress LLC SKI-178 | 1259484-97-3 | 99.3% | 10 MG
SKI-178 is a potent inhibitor of both sphingosine kinase-1 (SphK1) and SphK2. It exhibits cytotoxicity at IC50 concentrations ranging from 0.1 to 1.8 μM in various cancer cell lines, including those resistant to multiple agents. This compound has been shown to induce apoptosis in human acute myeloid leukemia cell lines through a CDK1-dependent mechanism.
- Potent sphingosine kinase-1 and SphK2 inhibitor
- Exhibits cytotoxicity in various cancer cell lines
- Induces apoptosis in a CDK1-dependent manner
- Inhibits leukemic progression in an MLL-AF9 mouse model
- Suitable for in vitro and in vivo studies
Aobchem 3-Bromo-N-cyclohexyl-2 6-dimethoxybenzamide | 97% | CAS 2755716-49-3 | C15H20BrNO3 | 1g
3-Bromo-N-cyclohexyl-2 6-dimethoxybenzamide | 97% | CAS 2755716-49-3 | C15H20BrNO3 | 1g
Medchemexpress LLC Zymostenol-d7 | 2260669-19-8 | 99.9% | 393.70 | 1 MG
Zymostenol-d7 is deuterium labeled 5a-Cholest-8-en-3b-ol.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC MRL-494 (hydrochloride) | 2699937-04-5 | 98.6% | 25 MG
MRL-494 hydrochloride is an antibacterial agent that acts as an inhibitor of β-barrel assembly machine A (BamA). It is impervious to efflux and the outer membrane permeability barrier, effectively inhibiting both Gram-positive and Gram-negative bacteria. The agent lethally disrupts the cytoplasmic membrane and inhibits outer membrane protein biogenesis by targeting BamA.
- Impervious to efflux and outer membrane permeability barrier
- Inhibits both Gram-positive and Gram-negative bacteria
- Lethally disrupts cytoplasmic membrane
- Inhibits outer membrane protein biogenesis
Medchemexpress LLC Ikk 16 (hydrochloride) | 1186195-62-9 | 99.9% | 520.09 | 25 MG
IKK 16 hydrochloride is an orally active IKK inhibitor. It also acts as a pan-PKD inhibitor and an ABCB1 inhibitor. This compound protects against LPS-induced multiple organ dysfunction, restores renal function, and alleviates fibrosis in acute kidney injury. It further attenuates cardiac dysfunction associated with polymicrobial sepsis in mice with type 2 diabetes mellitus (T2DM) by inhibiting the NF-κB pathway.
- Acts as an orally active IKK inhibitor
- Functions as a pan-PKD inhibitor
- Inhibits ABCB1
- Protects against LPS-induced multiple organ dysfunction
- Restores renal function and alleviates fibrosis in acute kidney injury
- Attenuates cardiac dysfunction associated with polymicrobial sepsis in mice with type 2 diabetes mellitus
- Inhibits IκB degradation and TNFα-stimulated expression in HUVEC cells
- Inhibits phosphorylation in specific LRRK2 cells
Medchemexpress LLC BIIL-260 hydrochlori | 100MG
BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist with anti-inflammatory activity BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable reversible and competitive manner has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1 7 nM[1]
Medchemexpress LLC ZZW-115 hydrochloride | 10122-45-9 | 98.1% | 573.97 | 1 ML
ZZW-115 hydrochloride is a potent NUPR1 inhibitor with a Kd of 2.1 μM. It demonstrates anticancer activity by inducing tumor cell death through both necroptosis and apoptosis.
- Potent NUPR1 inhibitor.
- Induces tumor cell death.
- Leads to necroptosis and apoptosis.
- Exhibits anticancer activity.
Medchemexpress LLC CX-6258 hydrochloride hydrate | 1353858-99-7 | 99.2% | 10 MG
A research-grade hydrochloride hydrate salt of a potent pan-Pim kinase inhibitor intended for laboratory research use. It selectively inhibits Pim-1, Pim-2, and Pim-3 with reported IC50 values of 5 nM, 25 nM, and 16 nM, respectively. Characterization data and quality documents (SDS, COA, LCMS) are provided by the supplier.