Aminophenols
Medchemexpress LLC PD153035 hydrochloride | 183322-45-4 | 99.5% | 50 MG
PD153035 hydrochloride is the hydrochloride salt of a potent epidermal growth factor receptor (EGFR) inhibitor used in biochemical and cellular research. It is supplied as a high-purity, well-characterized small-molecule reagent with defined solubility and storage recommendations.
- Potent EGFR inhibitor with reported Ki = 6 pM and IC50 = 25 pM.
- High purity: 99.48%.
- Molecular formula C16H15BrClN3O2; molecular weight 396.67 g/mol.
- Soluble in DMSO (4 mg/mL); insoluble in water (< 0.1 mg/mL).
- Recommended storage: solid at 4°C; in solution -80°C (6 months) or -20°C (1 month).
- Supplied as a 50 mg package for research use.
Medchemexpress LLC MRL-494 hydrochloride | 2699937-04-5 | 98.6% | 1 MG
MRL-494 hydrochloride is an antibacterial agent that functions as an inhibitor of β-barrel assembly machine A (BamA), remaining impervious to efflux and the outer membrane permeability barrier. It effectively inhibits both Gram-positive and Gram-negative bacteria by lethally disrupting the cytoplasmic membrane and inhibiting Outer Membrane Proteins (OMPs) biogenesis.
- Antibacterial agent
- Inhibitor of β-barrel assembly machine A (BamA)
- Impervious to efflux and the outer membrane permeability barrier
- Inhibits gram-positive bacteria
- Inhibits gram-negative bacteria
- Lethally disrupts the cytoplasmic membrane
- Inhibits outer membrane proteins (OMPs) biogenesis
![Medchemexpress LLC N-[1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide | 1259484-97-3 | 99.3% | 394.42 g/mol | C21H22N4O4 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000262954.png-250.jpg)
Medchemexpress LLC N-[1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide | 1259484-97-3 | 99.3% | 394.42 g/mol | C21H22N4O4 | 5 MG
SKI-178 is a small-molecule inhibitor of sphingosine kinase 1 (SphK1) and sphingosine kinase 2 (SphK2) that induces apoptosis in various cancer cell lines. It is provided as a high-purity research reagent for in vitro studies, with reported cytotoxic activity in the low micromolar range.
- Potent SphK1 and SphK2 inhibition
- Cytotoxic in cancer cell lines at low micromolar concentrations
- High purity suitable for research applications
- Available in multiple package sizes for screening and follow-up studies
- Molecular weight 394.42 and formula C21H22N4O4
Matrix Scientific 1-(4-HYDROXYPHENYL)PIPERAZI-10
1-(4-hydroxyphenyl)piperazine Mf C10h14n2o Mw 178.24 Cas 56621-48-8 Mdl MFCD00066156
![Medchemexpress LLC 7-[3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propoxy]-1H-quinolin-2-one hydrochloride | 1329509-60-5 | 99.0% | 427.97 g·mol⁻¹ | C24H30ClN3O2 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241642.png-250.jpg)
Medchemexpress LLC 7-[3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propoxy]-1H-quinolin-2-one hydrochloride | 1329509-60-5 | 99.0% | 427.97 g·mol⁻¹ | C24H30ClN3O2 | 1 MG
OPC 4392 hydrochloride is a small-molecule dopamine receptor modulator used in preclinical pharmacology research. It functions as a presynaptic dopamine autoreceptor agonist and a postsynaptic D2 receptor antagonist, and has been applied in animal studies to reverse reserpine-induced dopamine depletion and reduce apomorphine-induced behaviors.
- Acts as presynaptic dopamine autoreceptor agonist and postsynaptic D2 antagonist.
- Demonstrated efficacy in reversing reserpine-induced dopamine depletion in animal studies.
- Inhibits apomorphine-induced stereotypic and climbing behaviors in rodent models.
- High purity (98.99%) suitable for research applications.
- White to off-white solid, convenient for handling and formulation.
- Recommended sealed storage away from moisture; in solvent store at -80°C for long-term preservation.
Medchemexpress LLC Fasudil hydrochloride | 105628-07-7 | MFCD00943198 | 100.0% | 327.83 g/mol | C14H18ClN3O2S | 100 MG
Fasudil hydrochloride is the hydrochloride salt of fasudil, a nonspecific RhoA/ROCK inhibitor used in research to investigate Rho-kinase-mediated signaling and kinase activity. It has CAS 105628-07-7, molecular formula C14H18ClN3O2S, and a molecular weight of 327.83 g/mol. The compound is supplied as a high-purity research reagent and is soluble in water and DMSO at the concentrations indicated on the product datasheet.
- Nonspecific RhoA/ROCK inhibitor for biochemical and cellular studies.
- Hydrochloride salt form for improved aqueous solubility.
- High purity (99.97%) suitable for research applications.
- Molecular weight 327.83 g/mol; formula C14H18ClN3O2S.
- Solubility: H2O 55 mg/mL (requires ultrasonic), DMSO ≥ 31 mg/mL.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Delapril hydrochloride | 83435-67-0 | MFCD00884619 | 98.0% | 489.00 | C26H33ClN2O5 | 50 MG
Delapril hydrochloride is the hydrochloride salt of delapril, a lipophilic angiotensin-converting enzyme (ACE) inhibitor commonly used in cardiovascular research. Supplied for research use only, the compound is characterized for identity and analytical purity to support experimental studies.
- Hydrochloride salt form for improved solubility and stability.
- High purity: 98.0% (NMR).
- Molecular formula C26H33ClN2O5; molecular weight 489.00.
- Available in solid quantities including 50 mg.
- Analytical documentation available: COA and SDS.
- Intended for in vitro and preclinical ACE inhibition studies.
Medchemexpress LLC AM-92016 hydrochloride | 133229-11-5 | 99.3% | 483.84 g/mol | C19H25Cl3N2O4S | 10 MG
AM-92016 hydrochloride is a research-grade small molecule that selectively blocks the rectifier potassium current (IK), delaying IK-mediated repolarization and restricting action potential duration. It is supplied as a high-purity solid intended for use in electrophysiology and ion-channel research.
- Specific blocker of rectifier potassium current (IK).
- Suitable for electrophysiology and ion-channel research.
- High purity (99.3%) for reliable experimental results.
- Solid, light yellow to yellow appearance.
- Storage: sealed at 4°C; in solvent -80°C (6 months) or -20°C (1 month).
- Pack size 10 mg for small-scale studies.
eMolecules Medchem Express / SKI-178 / 5mg / 599150633 / HY-12892 / / 1259484-97-3 / MFCD01913555 / 394.431 / C21H22N4O4
Medchem Express / SKI-178 / 5mg / 599150633 / HY-12892 / / 1259484-97-3 / MFCD01913555 / 394.431 / C21H22N4O4
Medchemexpress LLC UNC9994 hydrochloride | 2108826-33-9 | 99.5% | 457.84 | 10 MG
UNC9994 hydrochloride is a functionally selective, β-arrestin-biased dopamine D2 receptor (D2R) agonist. It selectively activates β-arrestin recruitment and signaling, demonstrating antipsychotic-like activity. It also acts as an antagonist of Gi-regulated cAMP production and a partial agonist for D2R/β-arrestin-2 interactions.
- Selectively activates β-arrestin recruitment and signaling.
- Antagonist of Gi-regulated cAMP production.
- Partial agonist for D2R/β-arrestin-2 interactions.
- Shows antipsychotic-like activity.
- Induces D2-mediated β-arrestin-2 translocation with EC50s of 6.1 nM and 448 nM.
- Acts as an antagonist at 5HT2A and 5HT2B receptors.
- Acts as an agonist at 5HT2C and 5HT1A receptors.
Medchemexpress LLC AM-92016 hydrochloride | 133229-11-5 | MFCD00673947 | 99.3% | 483.84 | C19H25Cl3N2O4S | 1 ML
AM-92016 hydrochloride is a small-molecule blocker of delayed rectifier potassium currents (IK), commonly used in electrophysiology and cardiovascular research to modulate action potential duration. It is supplied both as a solid and as a ready-to-use solution to support in vitro pharmacology and ion-channel assays.
- Blocks delayed rectifier potassium channels (IK) and shortens action potential duration.
- Supplied as a 10 mM solution in DMSO or as a dry solid for custom preparation.
- High purity suitable for research use (reported ~99.3%).
- Molecular weight 483.84 and CAS 133229-11-5 for clear identification.
- Available in small-quantity formats compatible with pharmacological assays.
Medchemexpress LLC SKI-I | 5MG
SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK) with an IC50 of 1 2 M for ST-hSK SKI-I also inhibits hERK2 (IC50 11 M) SKI-I induces apoptosis in tumor cell lines[1][2]
Medchemexpress LLC HJC0416 hydrochloride | 2415263-08-8 | 98.7% | 429.32 g/mol | C18H18Cl2N2O4S | 25MG
HJC0416 hydrochloride is the hydrochloride salt of HJC0416, a potent, orally active small-molecule STAT3 inhibitor used in preclinical anticancer research. Supplied as a white to off-white solid with high chemical purity, it is intended for in vitro and in vivo studies assessing STAT3 pathway modulation.
- Potent STAT3 inhibition in preclinical models.
- Oral activity demonstrated in animal studies.
- High purity suitable for research applications.
- Available in small research pack sizes, including 25 mg.
- Store protected from light and under inert gas at recommended temperatures.
Medchemexpress LLC HY-112149 10mg Medchemexpress, ZL0420 CAS:2230496-80-5 Purity:>98%
Medchemexpress, HY-112149 10mg ZL0420 CAS:2230496-80-5 ZL0420 is a potent and selective bromodomain-containing protein 4 (BRD4) inhibitor with IC50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Ly-266,097 hydrochloride | 172895-39-5 | MFCD00949080 | ≥98.0% | 407.3 g/mol | C21H23ClN2O2 · HCl | 100 MG
LY266097 hydrochloride is the hydrochloride salt of LY266097, a selective antagonist of the serotonin 5-HT2B receptor used as a research tool in pharmacology and structural biology studies.
- Selective 5-HT2B receptor antagonist for receptor pharmacology studies.
- Supplied as the hydrochloride salt for improved solubility and handling.
- High purity suitable for in vitro and structural biology applications.
- Available in small research quantities for assay development and screening.