Aminophenols
Aobchem 3-Bromo-N-cyclohexyl-2 6-dimethoxybenzamide | 97% | CAS 2755716-49-3 | C15H20BrNO3 | 250mg
3-Bromo-N-cyclohexyl-2 6-dimethoxybenzamide | 97% | CAS 2755716-49-3 | C15H20BrNO3 | 250mg
Medchemexpress LLC ST-836 (hydrochloride) | 1415564-68-9 | C23H35ClN4OS | 25 MG
ST-836 hydrochloride is a potent dopamine receptor ligand with Ki values of 4.5 nM and 132 nM for D3 and D2 receptors, respectively. It has potential for Parkinson's disease. The salt form typically offers enhanced water solubility and stability compared to the free form, while maintaining comparable biological activity at equivalent molar concentrations.
- Potent dopamine receptor ligand
- Targets D3 receptor (Ki: 4.5 nM)
- Targets D2 receptor (Ki: 132 nM)
- Potential for Parkinson's disease treatment
- Enhanced water solubility and stability (salt form)
- Store solid at 4°C, sealed, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture
eMolecules 56520-98-0 | 4-ETHYL-2-NITROPHENOL | MFCD16742721 | 1g
AstaTech | 4-ETHYL-2-NITROPHENOL | 1g | 268489544 | 36967 | 95.000 | 56520-98-0 | MFCD16742721 | 167.164 | C8H9NO3
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Medchemexpress LLC Melatonin-d7 | 615251-68-8 | 98.0% | C13H9D7N2O2 | 1 MG
Melatonin-d7 is a deuterium-labeled version of melatonin, a hormone produced by the pineal gland. It activates melatonin receptors and is involved in sleep, exhibiting significant antioxidative and anti-inflammatory properties. Melatonin-d7 also acts as a selective ATF-6 inhibitor, inducing apoptosis in human hepatoma cells by downregulating COX-2, and can reduce palmitic acid-induced apoptosis in mouse granulosa cells through endoplasmic reticulum stress.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Rs 17053 hydrochloride | 169505-93-5 | 99.9% | 449.41 g/mol | C24H30Cl2N2O2 | 10 MG
RS 17053 hydrochloride is a potent, selective α1A adrenoceptor antagonist for pharmacological research. It exhibits high affinity in native membranes (pKi 9.1) and functional potency (pA2 9.8), with marked selectivity versus α1B and α1D subtypes. The material is supplied as a high-purity solid and is provided in multiple sizes and a DMSO solution format for laboratory use.
- Potent, selective α1A adrenoceptor antagonist with reported pKi 9.1 and pA2 9.8.
- Substantial selectivity versus α1B and α1D receptor subtypes.
- High purity suitable for sensitive pharmacology assays.
- Available as a solid and as a ready-to-use DMSO solution for convenience.
- Intended for research use in receptor binding and functional studies.
Medchemexpress LLC NG-Nitroarginine methyl ester hydrochloride | 51298-62-5 | 99.89% | 269.69 | 10 G
NG-Nitroarginine methyl ester hydrochloride | 51298-62-5 | 99.89% | 269.69 | 10 G
Medchemexpress LLC AFM-30a hydrochloride | 99.8% | 502.97 | 1 MG
AFM-30a hydrochloride is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. It binds to PAD2 with an EC50 value of 9.5 μM and inhibits H3 citrullination with an EC50 value of 0.4 μM. This product is suitable for research into certain cancers and various autoimmune diseases, including rheumatoid arthritis, multiple sclerosis, lupus, and ulcerative colitis.
- Potent and selective PAD2 inhibitor.
- Inhibits H3 citrullination.
- Useful for cancer research.
- Useful for autoimmune disease research.
- Suppresses NLRP3 signaling.
- Decreases airway remodeling.
- Shows low cell cytotoxicity.
Medchemexpress LLC IKK 16 hydrochloride | 1186195-62-9 | 99.95% | 520.09 | 10 MM * 1 ML
IKK 16 hydrochloride is an orally active IKK inhibitor, also acting as a pan-PKD and ABCB1 inhibitor. It protects against LPS-induced multiple organ dysfunction, restores renal function, alleviates fibrosis in acute kidney injury, and attenuates cardiac dysfunction by inhibiting the NF-κB pathway.
- Inhibits IκB degradation and TNFα-stimulated expression of adhesion molecules.
- Acts as an ATP-competitive inhibitor of PKD1 and inhibits PKCα and PKCδ.
- Protects against LPS-induced multiple organ dysfunction.
- Improves renal function and prevents fibrosis after acute kidney injury.
- Suppresses systemic TNFα levels and inhibits neutrophil extravasation.
- Reduces cardiac dysfunction and NF-κB pathway activation in sepsis models.
Medchemexpress LLC RGX-104 hydrochloride | 610318-03-1 | 99.9% | 632.54 | 10 MG
RGX-104 hydrochloride is a small-molecule LXR agonist that modulates innate immunity through the transcriptional activation of the ApoE gene. It is intended for research use only.
- Modulates innate immunity via transcriptional activation of the ApoE gene.
- Potential anti-cancer activity through suppression of various cancer types, including lung cancer, melanoma, glioblastoma, ovarian, renal cell, triple-negative breast, and colon cancer.
- Induces tumor regression in some cases.
- Available in various quantities.