Aminophenols
Cayman Chemical Methylhexanamine (hydrochloride), Purity: ≥95% (mixture of diastereomers), CAS: 13803-74-2, 10 mg
A simple aliphatic amine that was once marketed as a nasal decongestant but is now sold as a bodybuilding supplement; sold as a mild stimulant in the form of party pills; intended for forensic or research purposes
Medchemexpress LLC S65487 hydrochloride | 1644543-95-2 | 99.7% | 753.72 | 1 ML
S65487 hydrochloride (VOB560 hydrochloride) is a potent and selective Bcl-2 inhibitor, acting as a proagent of S55746. It is effective against BCL-2 mutations like G101V and D103Y, while showing low affinity for MCL-1, BFL-1, and BCL-XL. This compound is known to induce apoptosis and exhibits anticancer activities.
- Potent and selective Bcl-2 inhibitor.
- Proagent of S55746.
- Active against BCL-2 mutations (G101V and D103Y).
- Low affinity with MCL-1, BFL-1, and BCL-XL.
- Induces apoptosis.
- Exhibits anticancer activities.
- Induces complete regression in BCL-2-dependent RS4;11 tumors in vivo after a single intravenous administration.
- Shows strong and persistent tumor regression in xenograft models of lymphoid malignancies in mouse and rat when combined with the MCL-1-specific inhibitor S64315/MIK665.
![Medchemexpress LLC Glycine, N-[(3R)-3-([1,1'-biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methyl-, hydrochloride | 200006-08-2 | MFCD09971056 | 98.2% | 429.91 g/mol | C24H25ClFNO3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239904.png-250.jpg)
Medchemexpress LLC Glycine, N-[(3R)-3-([1,1'-biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methyl-, hydrochloride | 200006-08-2 | MFCD09971056 | 98.2% | 429.91 g/mol | C24H25ClFNO3 | 5 MG
ALX-5407 hydrochloride is the hydrochloride salt of a research-grade small-molecule inhibitor of the glycine transporter GlyT1. It is used to probe glycine uptake and NMDA receptor modulation in preclinical studies and is supplied as a characterized solid with high purity and documented handling conditions.
- Potent GlyT1 inhibitor with reported IC50 ≈ 3 nM.
- Selective for GlyT1 over GlyT2 and NMDA receptors.
- High purity solid suitable for research applications.
- Characterized molecular weight and formula for reproducibility.
- Recommended sealed storage at 4°C; solvent storage conditions documented.
Medchemexpress LLC Dtagv-1 hydrochloride | 2624313-16-0 | 99.9% | C68H91ClN6O14S | 25 MG
dTAGV-1 hydrochloride is a potent and selective PROTAC degrader designed for FKBP12F36V-tagged proteins. This compound is capable of inducing degradation of FKBP12F36V-Nluc both in vitro and in vivo.
- Potent and selective degrader of FKBP12F36V-tagged proteins
- Induces degradation of FKBP12F36V-Nluc in vivo
- Composed of a Target Protein Ligand, a Linker, and a VHL Ligand
- Intended for research use only
Medchemexpress LLC Benzamide, 4-fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl] ethyl] HCl | 286369-38-8 | 99.9% | 443.94 | 10 MG
S-14506 hydrochloride is a potent 5-HT1A agonist and a 5-HT2A/2C antagonist. It also demonstrates dopamine antagonist properties by blocking dopamine D2 receptors. This compound effectively inhibits the in vivo binding of [3H]raclopride in the striatum and olfactory bulbs, holding potential for research as an anxiolytic agent.
- Potent 5-HT1A agonist
- 5-HT2A/2C antagonist
- Dopamine D2 receptor blocker
- Inhibits [3H]raclopride binding
- Potential anxiolytic agent
Medchemexpress LLC Guanine hydrochloride | 635-39-2 | MFCD00213670 | 98.8% | 187.59 g/mol | C5H6ClN5O | 50mg
Guanine hydrochloride is one of the fundamental components of nucleic acids (DNA and RNA) It is a purine derivative composed of a fused pyrimidine-imidazole ring system with conjugated double bonds Guanine hydrochloride has the potential to serve as a large-capacity nitrogen reservoir[1]
Medchemexpress LLC MRL-494 hydrochloride | 2699937-04-5 | 98.6% | 1 ML
MRL-494 hydrochloride is an antibacterial agent that acts as an inhibitor of β-barrel assembly machine A (BamA). It is impervious to efflux and the outer membrane permeability barrier, demonstrating inhibitory effects on both Gram-positive and Gram-negative bacteria. MRL-494 lethally disrupts the cytoplasmic membrane and inhibits outer membrane proteins (OMPs) biogenesis by targeting BamA from outside the outer membrane.
- Acts as an inhibitor of β-barrel assembly machine A (BamA).
- Impervious to efflux and the outer membrane permeability barrier.
- Effective against Gram-positive bacteria, including Staphylococcus aureus COL (MIC of 12.5 μM).
- Effective against Gram-negative bacteria, including E. coli JCM158 (MIC of 25 μM).
- Lethally disrupts the cytoplasmic membrane.
- Inhibits outer membrane proteins (OMPs) biogenesis by targeting BamA.
Medchemexpress LLC SBI-810 hydrochloride | 2772746-58-2 | 99.6% | 483.05 | C27H35ClN4O2 | 10 MG
SBI-810 hydrochloride is a β-arrestin-biased allosteric modulator of the neurotensin receptor 1 (NTSR1) supplied as the hydrochloride salt for research use. Provided as a solid with high analytical purity, it is intended for in vitro pharmacology and preclinical signaling or analgesia studies.
- β-arrestin-biased NTSR1 allosteric modulator for receptor signaling studies.
- High purity; typically ≥99.5% by supplier assay.
- Molecular weight 483.05; formula C27H35ClN4O2.
- Available in small-mass pack sizes suitable for in vitro and preclinical work.
- Option for 10 mM solution in DMSO, ready for reconstitution.
- Store sealed at 4°C; in solution store at -80°C for long-term storage.
Medchemexpress LLC Nefopam (hydrochloride) | 23327-57-3 | 99.9% | 1 ML
Nefopam hydrochloride is a centrally-acting, non-opioid analgesic drug used for the relief of moderate to severe pain. It targets β-catenin protein levels in mesenchymal cells both in-vitro and in-vivo. This non-opioid, non-steroidal analgesic is derived from benzoxazocine. Constitutively elevated β-catenin leads to delayed and fibrous fracture repair, and Nefopam inhibits β-catenin mediated signaling during skin wound repair.
- Centrally-acting, non-opioid analgesic
- Relieves moderate to severe pain
- Targets β-catenin protein levels
- Inhibits β-catenin mediated signaling
Medchemexpress LLC Tas4464 hydrochloride | 1848959-11-4 | 98.9% | 1 ML
TAS4464 hydrochloride is a long-acting, highly selective covalent inhibitor that targets the NEDD8-activating enzyme (NAE) with an IC50 of 0.955 nM. It blocks the neddylation pathway, leading to the accumulation of CRL ubiquitin ligase substrates and subsequent induction of tumor cell apoptosis. This compound exhibits broad-spectrum antiproliferative and cytotoxic antitumor activity against various hematologic and solid tumor cell lines, as well as patient-derived tumor cells, while possessing a wide therapeutic window without obvious toxicity.
- Highly selective covalent inhibitor of NEDD8-activating enzyme (NAE)
- Blocks the neddylation pathway
- Induces tumor cell apoptosis
- Exhibits broad-spectrum antitumor activity
- Possesses a wide therapeutic window
- Suitable for research in hematologic malignancies and solid tumors