Aminophenols
Medchemexpress LLC CBB1007 hydrochloride | 2070014-96-7 | C27H39Cl5N8O4 | 50 MG
CBB1007 hydrochloride is a reversible and selective LSD1 inhibitor. It significantly blocks the demethylase activity of LSD1 on H3K4Me2 and H3K4Me, showing selectivity for LSD1 over LSD2 or JARID1A. This compound induces differentiation-related genes in pluripotent cells and is studied in non-pluripotent cancer research, targeting teratocarcinoma, embryonic carcinoma, and seminoma.
- Reversible and selective LSD1 inhibitor
- Blocks demethylase activity of LSD1 on H3K4Me2 and H3K4Me
- Induces differentiation-related genes in pluripotent cells
- Targeted in non-pluripotent cancer research
Medchemexpress LLC RS 67333 hydrochloride | 168986-60-5 | 99.7% | 389.36 g/mol | C19H30Cl2N2O2 | 50 MG
RS 67333 hydrochloride is the hydrochloride salt of a selective partial agonist of the 5-HT4 (serotonin) receptor. Supplied as a solid research reagent, it is used in neuroscience studies of 5-HT4 receptor pharmacology, neuroprotection, and related pathways. For research use only.
- Selective partial agonist of 5-HT4 receptor.
- High purity (99.7%).
- Supplied as a solid suitable for in vitro and in vivo studies.
- Stable when stored sealed at 4°C, away from moisture.
- Available in small laboratory quantities for research applications.
Medchemexpress LLC AFM-30a hydrochloride | 99.8% | 502.97 | 100 MG
AFM-30a hydrochloride is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. It binds to PAD2 with an EC50 value of 9.5 μM and inhibits H3 citrullination with an EC50 value of 0.4 μM. This compound is suitable for research into certain cancers and various autoimmune diseases, including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis.
- Exhibits high potency and selectivity for PAD2.
- Effectively inhibits H3 citrullination.
- Has shown low cytotoxicity in HEK293T/PAD2 cells.
- Can suppress NLRP3 signaling, decreasing airway remodeling in PAD2-/- transgenic mice.
Medchemexpress LLC AM-92016 hydrochloride | 133229-11-5 | 99.3% | 483.84 g/mol | C19H25Cl3N2O4S | 10 MG
AM-92016 hydrochloride is a research-grade small molecule that selectively blocks the rectifier potassium current (IK), delaying IK-mediated repolarization and restricting action potential duration. It is supplied as a high-purity solid intended for use in electrophysiology and ion-channel research.
- Specific blocker of rectifier potassium current (IK).
- Suitable for electrophysiology and ion-channel research.
- High purity (99.3%) for reliable experimental results.
- Solid, light yellow to yellow appearance.
- Storage: sealed at 4°C; in solvent -80°C (6 months) or -20°C (1 month).
- Pack size 10 mg for small-scale studies.
Medchemexpress LLC Hlcl-61 hydrochloride | 1158279-20-9 | MFCD09446681 | 99.9% | 380.91 g·mol⁻¹ | C23H25ClN2O | 100 MG
HLCL-61 hydrochloride is a research-grade small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5), intended for in vitro and preclinical studies. It is supplied with analytical data and handling guidance and is not for human or clinical use.
- Potent and selective PRMT5 inhibition for cellular studies.
- High chemical purity suitable for research applications.
- Available in multiple pack sizes and ready-to-use DMSO solutions.
- Supplied with supporting datasheet and analytical information.
- Intended for controlled laboratory use with recommended storage conditions.
Medchemexpress LLC GSK2945 (hydrochloride) | 2517771-89-8 | 98.5% | 457.80 | 1 ML
GSK2945 hydrochloride is a tertiary amine and a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. It enhances cholesterol 7α-hydroxylase (CYP7A1) levels and cholesterol metabolism. For research use only.
- Highly specific Rev-erbα/REV-ERBα antagonist.
- Enhances cholesterol 7α-hydroxylase (CYP7A1) levels.
- Promotes cholesterol metabolism.
- Suitable for research applications.
eMolecules 65646-68-6 | Fenretinide | Apollo Scientific | MFCD00792674 | 391.555 | C26H33NO2 | 99.000 | C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)Nc1ccc(O)cc1 | 100mg | 562460510
Fenretinide | Apollo Scientific | 65646-68-6 | MFCD00792674 | 391.555 | C26H33NO2 | 99.000 | C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)Nc1ccc(O)cc1 | 100mg | 562460510
Medchemexpress LLC LCKLSL hydrochloride | 533902-29-3 | 98.05% | 712.34 | 25 MG
LCKLSL hydrochloride is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. It potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2. Additionally, this peptide has anti-angiogenic roles and inhibits the generation of plasmin.
- N-terminal hexapeptide
- Acts as a competitive annexin A2 (AnxA2) inhibitor
- Potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2
- Inhibits the generation of plasmin
- Exhibits anti-angiogenic properties
- Suppresses VEGF-induced tPA activity under hypoxic conditions
- Decreases vascular length in angiogenesis models
Medchemexpress LLC V-9302 hydrochloride | 2416138-42-4 | 99.1% | 575.14 | 25 MG
V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. It selectively and potently targets the amino acid transporter ASCT2 (SLC1A5), but not ASCT1. It inhibits ASCT2-mediated glutamine uptake with an IC50 of 9.6 μM in HEK-293 cells.
- Inhibits ASCT2-mediated glutamine uptake in human cells.
- Shows improved potency over gamma-L-glutamyl-p-nitroanilide.
- Attenuates cancer cell growth and proliferation.
- Increases cell death and oxidative stress.
- Prevents tumor growth in xenograft models.
- Elicits strong growth inhibition in xenograft models when combined with CB-839.
- Reduces tumor growth.
Cambridge Isotope Laboratories Acetaminophen (ring-13C6 98%) 1 mg
Acetaminophen (ring-13C6 98%) 1 mg
Medchemexpress LLC Guvacine hydrochloride | 6027-91-4 | 99.9% | 163.60 g·mol⁻¹ | C6H10ClNO2 | 100 MG
Guvacine hydrochloride is a research reagent used to inhibit GABA uptake in neuropharmacology and biochemical studies. It is supplied as a white to off-white solid and is available in both solid and small-solution formats for in vitro experiments.
- Functions as a GABA uptake inhibitor for neuropharmacology research.
- High purity (~99.9%) minimizes impurities in assays.
- Available as solids and as a DMSO solution for experimental flexibility.
- White to off-white solid suitable for analytical and in vitro use.
- Molecular weight 163.60 g·mol⁻¹ supports accurate stoichiometry calculations.