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Filtered Search Results
Cayman Chemical NGaminoLArginine hydrochlori
Inhibits nNOS, iNOS, and eNOS (Ki = 0.3, 3, and 2.5 μM, respectively); can be used both in cell culture and in vivo
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eMolecules 6291-01-6 | Cyclobutanamine hydrochloride | ChemScene | MFCD00034953 | 107.580 | C4H10ClN | 97.000 | Cl.NC1CCC1 | 1g | 582633316
Cyclobutanamine hydrochloride | ChemScene | 6291-01-6 | MFCD00034953 | 107.580 | C4H10ClN | 97.000 | Cl.NC1CCC1 | 1g | 582633316
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Medchemexpress LLC CGP71683 hydrochloride | 192322-50-2 | MFCD07783999 | 99.4% | 512.07 | C26H30ClN5O2S | 10 MG
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CGP71683 hydrochloride is the hydrochloride salt of a selective neuropeptide Y Y5 receptor antagonist used as a research tool in neuroscience and endocrinology. It is supplied as a high-purity solid for non-clinical laboratory use, with supporting datasheet and certificate of analysis available.
- Selective antagonist for the neuropeptide Y Y5 receptor (Ki ~1.3 nM).
- High reported purity, 99.4%.
- Molecular weight 512.07 g/mol; chemical formula C26H30ClN5O2S.
- CAS number 192322-50-2 for unambiguous identification.
- Solid powder suitable for dissolution in appropriate solvents for assays.
- Supplied with datasheet and certificate of analysis for quality assurance.
- Available in small milligram pack sizes for screening and mechanistic studies.
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Medchemexpress LLC Delapril hydrochloride | 83435-67-0 | 98.0% | 489.00 g·mol⁻¹ | C26H33ClN2O5 | 1 ML
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Delapril hydrochloride is the hydrochloride salt of delapril, an angiotensin-converting enzyme (ACE) inhibitor used in cardiovascular research and preclinical studies. The compound is provided both as a ready-to-use 10 mM solution in DMSO (1 mL) and in solid quantities. Typical reported purity is 98.0% and the molecular weight is 489.00 g·mol⁻¹. Store and handle according to supplier safety data.
- ACE inhibitor used in cardiovascular research.
- Available as 10 mM solution in DMSO (1 mL) and as solid quantities.
- High reported purity, 98.0%.
- Molecular weight 489.00 g·mol⁻¹.
- CAS number 83435-67-0 for unambiguous identification.
- Store solid at 4°C; store solution frozen for long-term stability.
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TARGETMOL CHEMICALS INC Biotin-4-aminophenol 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Biotin-4-aminophenol (BP) is a selective and potent biotin-phenol analog that works by generating free radicals and binding to tyrosine residues in proteins. Purity 98.99%
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Medchemexpress LLC Hlcl-61 hydrochloride | 1158279-20-9 | MFCD09446681 | 99.9% | 380.91 g·mol⁻¹ | C23H25ClN2O | 100 MG
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HLCL-61 hydrochloride is a research-grade small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5), intended for in vitro and preclinical studies. It is supplied with analytical data and handling guidance and is not for human or clinical use.
- Potent and selective PRMT5 inhibition for cellular studies.
- High chemical purity suitable for research applications.
- Available in multiple pack sizes and ready-to-use DMSO solutions.
- Supplied with supporting datasheet and analytical information.
- Intended for controlled laboratory use with recommended storage conditions.
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MEDCHEMEXPRESS LLC AMODIAQUIN DIHYDROCHLORIDE DI
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501874499 AMODIAQUIN DIHYDROCHLORIDE DI
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Medchemexpress LLC Bepridil hydrochloride | 68099-86-5 | MFCD00065498 | 99.8% | 403.0 g/mol | C24H35ClN2O | 25 MG
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Bepridil hydrochloride is a non-selective calcium channel blocker with antianginal activity, commonly used in cardiovascular and ion channel research to study calcium-mediated cardiac effects. The compound is provided as the hydrochloride salt (CAS 68099-86-5) with molecular formula C24H35ClN2O and molecular weight 403.0 g/mol.
- Non-selective calcium channel blocker used in cardiac and ion channel studies.
- Useful for investigating calcium-dependent electrophysiology and myocardial contractility.
- Hydrochloride salt form enhances solubility for assay preparation.
- Intended for in vitro and ex vivo research applications.
- Well-characterized chemical identifiers: CAS 68099-86-5; molecular formula C24H35ClN2O; molecular weight 403.0 g/mol.
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Medchemexpress LLC Scopine hydrochloride | 85700-55-6 | 99.69% | 50 MG
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Scopine hydrochloride is a metabolite of Scopolamine and a brain-targeting compound. It significantly increases the brain exposure of Chlorambucil, thereby enhancing its anti-glioma activity. This compound can be utilized in targeted therapy research for brain gliomas.
- Metabolite of scopolamine
- Brain-targeting compound
- Increases brain exposure of Chlorambucil
- Enhances anti-glioma activity
- Useful in targeted therapy research for brain gliomas
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Medchemexpress LLC Daurk-4 (hydrochloride) | 99.44% | 1071.93 | 25 MG
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dAURK-4 hydrochloride, an Alisertib derivative, is a potent and selective PROTAC AURKA (Aurora A) degrader with anticancer effects. It is composed of a ligand for the target protein, a linker, and a ligand for E3 ligase Thalidomide-O-COOH.
- Potent and selective PROTAC AURKA degrader
- Demonstrates dose-dependent degradation of AURKA
- Inhibits protein level of AURKA in MM.1S cells
- Composed of a ligand for the target protein, a linker, and a ligand for E3 ligase
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Medchemexpress LLC A-350619 hydrochloride | 1217201-17-6 | ≥99.0% | 425.41 g/mol | C21H25ClN2OS·HCl | 10 MG
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A-350619 hydrochloride is a small-molecule soluble guanylate cyclase (sGC) activator used in preclinical research. It enhances cGMP production by activating basal sGC and synergizing with nitric oxide, producing vasodilatory effects such as cavernosum smooth muscle relaxation and increased blood flow in animal models. The material is supplied as a hydrochloride salt for improved solubility.
- High purity suitable for in vitro and in vivo studies.
- Soluble hydrochloride salt with good DMSO and aqueous solubility.
- Activates soluble guanylate cyclase and enhances NO-mediated signaling.
- Demonstrated vasodilatory and penile erection effects in rodent models.
- Store at 4°C to maintain stability.
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Medchemexpress LLC AT7519 Hydrochloride | 902135-91-5 | 99.2% | C16H18Cl3N5O2 | 100 MG
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AT7519 Hydrochloride is a potent inhibitor of Cyclin-Dependent Kinases (CDKs), exhibiting strong inhibitory activity against CDK1, CDK2, CDK4 to CDK6, and CDK9. It induces dose-dependent cytotoxicity and apoptosis in MM cells and inhibits cell cycle progression in various human tumor cell lines. In preclinical studies, AT7519 Hydrochloride effectively inhibits tumor growth in both human MM and HCT116 xenograft mouse models.
- Potent inhibitor of CDKs (IC50 values range from <10 nM to 210 nM)
- Induces cytotoxicity and apoptosis in MM cells
- Overcomes cytokine and BMSC protective effects
- Inhibits RNA polymerase II CTD phosphorylation and RNA synthesis
- Inhibits cell cycle progression and induces apoptosis in tumor cell lines
- Reduces antiapoptotic protein levels
- Inhibits tumor growth in MM and HCT116 xenograft models
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eMolecules 5325-64-4 | Sarcosine amide hydrochloride | Chem-Impex | MFCD00058283 | 124.570 | C3H9ClN2O | 99.000 | Cl.CNCC(N)=O | 1g | 112449205
Sarcosine amide hydrochloride | Chem-Impex | 5325-64-4 | MFCD00058283 | 124.570 | C3H9ClN2O | 99.000 | Cl.CNCC(N)=O | 1g | 112449205
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Medchemexpress LLC Acetaminophen glucuronide sodium salt | 120595-80-4 | MFCD00153898 | ≥99.0% | 349.27 g/mol | C14H16NNaO8 | 1 MG
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Acetaminophen glucuronide sodium salt is the sodium salt of the primary glucuronide metabolite of acetaminophen. Supplied as a white to off-white solid, it is used as a reference standard in analytical chemistry, metabolite identification, and toxicology research.
- Primary glucuronide metabolite of acetaminophen.
- Supplied as a white to off-white solid, soluble in water.
- Molecular formula C14H16NNaO8 and molecular weight 349.27 g/mol.
- High purity (≥99.0%).
- Available in small pack sizes for analytical use (1 mg, 5 mg, 10 mg).
- Suitable as an analytical reference, calibration standard, and for toxicology assays.
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Apexbio Technology LLC Clemizole hydrochloride 1163-36-6 10mM (in 1mL DMSO)
Clemizole hydrochloride is a histamine H1 receptor antagonist reported to inhibit hepatitis C virus (HCV) replication by targeting the viral NS4B protein a component essential for viral RNA replication Clemizole demonstrates antiviral activity in vitro against HCV genotype 2a subgenomic replicons exhibiting an IC50 value around 8 mM When combined with HCV protease inhibitors (such as VX950 or SCH503034) clemizole displays synergistic antiviral effects In contrast additive antiviral effects occur in combination with interferon ribavirin or polymerase inhibitors Clemizole is utilized in research contexts aimed at evaluating its efficacy potential antiviral combinations metabolism pathways and pharmacokinetics relevant to its consideration as a therapeutic candidate for HCV infection
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