Aminophenols
Medchemexpress LLC AFM32a hydrochloride | 2988594-85-8 | 99.4% | 517.00 | 25 MG
This benzimidazole-based derivative is a potent and selective protein arginine deiminase 2 inhibitor. It exhibits superior selectivity for PAD2 over PAD4 (95-fold) and PAD3 (79-fold).
- Potent and selective protein arginine deiminase 2 inhibitor.
- Superior selectivity for PAD2 over PAD4 (95-fold) and PAD3 (79-fold).
Medchemexpress LLC AFM32a hydrochloride | 2988594-85-8 | 99.4% | 517.00 | 1 ML
AFM32a hydrochloride, also known as PAD2-IN-1 hydrochloride, is a potent and selective benzimidazole-based derivative that inhibits protein arginine deiminase 2 (PAD2). It demonstrates high selectivity, being 95-fold more selective for PAD2 over PAD4 and 79-fold more selective over PAD3.
- Potent and selective PAD2 inhibitor.
- Exhibits superior selectivity over PAD4 and PAD3.
- Effective in inhibiting histone H3 citrullination in HEK293T/PAD2 cells.
Medchemexpress LLC Afm32a hydrochloride | 2988594-85-8 | 99.4% | 517.00 | 1 MG
Afm32a hydrochloride | 2988594-85-8 | 99.4% | 517.00 | 1 MG
Medchemexpress LLC Afm32a hydrochloride | 2988594-85-8 | 99.7% | 517.00 g/mol | C25H30ClFN6O3 | 5 MG
AFM32a hydrochloride is a benzimidazole-derived small-molecule inhibitor selective for protein arginine deiminase 2 (PAD2). Supplied as the hydrochloride salt for research use, it is suitable for biochemical assays and target validation, demonstrating approximately 95-fold selectivity for PAD2 versus PAD4 and 79-fold versus PAD3.
- Potent PAD2 inhibition with high selectivity over PAD3 and PAD4.
- Hydrochloride salt form for improved solubility and handling.
- High purity (≈99.7%) appropriate for biochemical assays.
- Available in small-mass and DMSO solution formats for screening.
- Characterized with molecular formula and molecular weight for analytical use.