Cresols
eMolecules 519016-81-0 | 2-Amino-4-(2,5-dimethylphenyl)thiophene-3-carbonitrile | Combi-Blocks | MFCD02244485 | 228.310 | C13H12N2S | 95.000 | Cc1ccc(C)c(c1)-c1csc(N)c1C#N | 1g | 205395986
2-Amino-4-(2,5-dimethylphenyl)thiophene-3-carbonitrile | Combi-Blocks | 519016-81-0 | MFCD02244485 | 228.310 | C13H12N2S | 95.000 | Cc1ccc(C)c(c1)-c1csc(N)c1C#N | 1g | 205395986
Apexbio Technology LLC Cytochrome c fragment (93-108) 1mg
Cytochrome c fragment 93-108 is a peptide derived from cytochrome c a mitochondrial protein involved in apoptosis It is designed to interact with apoptotic protease activating factor-1 (Apaf-1) thereby promoting the assembly of the Apaf-1/caspase-9 apoptosome complex and regulating the caspase activation pathway Cytochrome c fragment 93-108 exerts its biological activity primarily through activation of the caspase cascade specifically the activation of caspase-9 and subsequent caspase-3 Based on these pharmacological properties cytochrome c fragment 93-108 holds research potential in studies of apoptosis-related signaling networks caspase activation pathways and drug screening targeting apoptosis regulators
Medchemexpress LLC M-PEG17-acid | 2346581-96-0 | 98.5% | C36H72O19 | 100 MG
m-PEG17-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These molecules employ the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Facilitates selective degradation of target proteins via the ubiquitin-proteasome system.
Apexbio Technology LLC EZ Cap Mouse CD80 mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Mouse CD80 mRNA encodes CD80P Binding to CD28 and CTLA-4 receptors on T cells CD80 modulates T-cell activation and inhibition CD80 interacting with CD28 promotes T-cell activation and proliferation enhancing immune responses Its binding to CTLA-4 provides inhibitory signals maintaining immune tolerance and preventing excessive immune reactions CD80 have emerged as therapeutic targets in various immunotherapies such as treatments for autoimmune diseases transplantation rejection and cancer immunotherapy EZ Cap Mouse CD80 mRNA (m1 HA tag) is provided at 1 mg/mL and expresses mouse CD86 cytokine fused with an HA tag facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Medchemexpress LLC Contactin-3/CNTN3 M 10ug
Contactin-3/CNTN3 protein facilitates cell surface interactions in nervous system development promoting neurite outgrowth and interacting with PTPRG to regulate neuronal growth and connectivity Contactin-3/CNTN3 Protein Mouse (HEK293 His) is the recombinant mouse-derived Contactin-3/CNTN3 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Interleukin-24 (IL-24) | >95.0% | 10UG
Animal-Free IL-24 Protein, Mouse (His) is a recombinant mouse interleukin-24 expressed in Escherichia coli and supplied lyophilized with a C-terminal 6xHis tag for research use in cell culture and in vitro assays. The product is highly pure and biologically active, with characterization by SDS-PAGE and functional ED50 data.
Medchemexpress LLC m-PEG7-CH2CH2COOH | 1093647-41-6 | >99.39% | 25 G
m-PEG7-CH2CH2COOH (CAS No. 1093647-41-6) is a non-cleavable, PEG-based linker used in the synthesis of antibody-drug conjugates (ADCs) and as a PROTAC linker. It is an essential component for developing targeted therapeutics due to its role in connecting active pharmaceutical ingredients to targeting moieties.
- Recommended storage for pure form: -20°C for 3 years, 4°C for 2 years.
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month.
- Shipping at room temperature is acceptable if duration is less than 2 weeks.
- Chemically identified as 4,7,10,13,16,19,22,25-Octaoxahexacosanoic acid.
Medchemexpress LLC NH-bis(m-PEG8) | 2055013-64-2 | C34H71NO16 | 25 MG
NH-bis(m-PEG8) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a protein of interest.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 1309241-34-6 | (4-((2-(2,5-Dimethylphenoxy)ethyl)amino)piperidin-1-yl)(pyridin-4-yl)methanone | 100mg
Ambeed | 44-Dihexyl-4H-cyclopenta[12-b54-b]dithiophene | 100mg | 633657988 | A181089 | 153312-86-8 | MFCD27923054 | 346.590 | C21H30S2
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Medchemexpress LLC M-PEG37-acid | 2924199-92-6 | N/A | >96.0% | C76H152O39 | 10MG
m-PEG37-acid is a carboxyl-terminated methoxy-polyethylene glycol (mPEG) linker with an average chain length of approximately 37 ethylene glycol units. It is designed for use as a PEG-based PROTAC linker or spacer in medicinal chemistry and bioconjugation workflows, providing hydrophilicity and flexible spacing between binding motifs while offering a reactive carboxyl terminus for conjugation.
- Carboxyl-terminated mPEG linker with ~37 ethylene glycol units.
- Enhances solubility and hydrophilicity of conjugates.
- Provides flexible spacer for PROTAC synthesis and bioconjugation.
- Terminal carboxyl enables standard amide or ester coupling reactions.
- Reported purity greater than 96% for research applications.
BIOHIPPO h/m KRT10 shRNA Set GFP Puro
h/m KRT10 shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated h/m keratin 10 (KRT10) shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse keratin 10 (KRT10) The shRNA has been validated to meet or exceed 70% KRT10 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC Calreticulin/CALR M 50ug
Recombinant mouse calreticulin (GST-tagged) is a calcium-binding molecular chaperone supplied lyophilized for biochemical, binding, and assay development applications. The protein is expressed in E. coli and formulated for stability and low endotoxin to support sensitive downstream experiments.
- Expressed in E. coli for high-yield production.
- N-terminal GST tag for purification and detection.
- Purity greater than 95% by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Lyophilized from Tris-HCl with trehalose for enhanced stability.
- Store at -20°C; aliquot after reconstitution to avoid repeated freeze-thaw.
Apexbio Technology LLC EZ Cap Mouse IL-36γ mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Mouse IL-36 mRNA encodes cytokine interleukin-36 (IL-36)Gamma primarily involved in inflammatory responses and immune regulation IL-36 acts through binding to the IL-36 receptor activating downstream signaling pathways like NF- B and MAPK promoting the release of inflammatory cytokines and activation of immune cells IL-36 is involved in multiple inflammatory disorders including psoriasis inflammatory bowel diseases and rheumatoid arthritis IL-36 may have pro-inflammatory functions in the pathological processes of these diseases making it a potential therapeutic target EZ Cap Mouse IL-36 mRNA (m1 HA tag) is supplied at 1 mg/mL It expresses mouse IL-36 cytokine fused with an HA tag facilitating subsequent detection With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Cambridge Isotope Laboratories 1 2 3 7 8-PentaCDF (unlabeled) 25 ng/mL in nonane 0 1 mL
1 2 3 7 8-PentaCDF (unlabeled) 25 ng/mL in nonane 0 1 mL
STA PHARMACEUTICAL US LLC Fmoc-L-2,3-Dimethylphe | 1 g | CAS 1270295-08-3 | MDL MFCD09842054
Fmoc-L-2,3-Dimethylphe is a Amino Acid reagent (Subcategory: Phe) sold by WuXi TIDES. Offered in 1 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1270295-08-3
- MDL: MFCD09842054
- InChIKey: DGFWPHOIYSZHRN-DEOSSOPVSA-N
- Molecular Weight: 415.489
- Molecular Formula: C26H25NO4
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3-dimethylphenyl)propanoic acid
- SMILES: O=C(O)[C@H](CC1=CC=CC(C)=C1C)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O