Cresols
BIOHIPPO h/m FGF17-sh-GFP-Puro
h/m FGF17-sh-GFP-Puro shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m FGF17 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse fibroblast growth factor 17 (FGF17) The shRNA has been validated to meet or exceed 70% knockdown of FGF17 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC M-CSF Rat 10ug
M-CSF Protein Rat is a pro-inflammatory cytokine binds to its receptor CSF1R and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes
STA Pharmaceutical Fmoc-L-3,4-Dimethylphe | 100 g | CAS 1217620-19-3 | MDL MFCD08458428
Fmoc-L-3,4-Dimethylphe is a Amino Acid reagent (Subcategory: Phe) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1217620-19-3
- MDL: MFCD08458428
- InChIKey: QMHIEEWTOGXGNA-DEOSSOPVSA-N
- Molecular Weight: 415.489
- Molecular Formula: C26H25NO4
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,4-dimethylphenyl)propanoic acid
- SMILES: O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N[C@@H](CC4=CC=C(C)C(C)=C4)C(O)=O
BIOHIPPO h/m NRP1-sh-GFP-BSD
h/m NRP1-sh-GFP-BSD shRNA lentiviral vector expressing GFP with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m NRP1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse neuropilin 1 (NRP1) The shRNA has been validated to meet or exceed 70% knockdown of NRP1 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO TetOn h/m MYC-sh-BSD
TetOn h/m MYC-sh-BSD shRNA lentiviral vector expressing with Blasticidin selection for studies in Each vial provides a nominal titer of 2x10E6 transducing units TU Validated h/m c-MYC shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse MYC proto-oncogene bHLH transcription factor (MYC) also known as c-MYC or cMYC The shRNA has been validated to meet or exceed 70% c-MYC knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
eMolecules 4962-29-2 | 4-Methoxy-3,5-dimethylphenol | Combi-Blocks | MFCD18432122 | 152.193 | C9H12O2 | 97.000 | COc1c(C)cc(O)cc1C | 1g | 457921793
4-Methoxy-3,5-dimethylphenol | Combi-Blocks | 4962-29-2 | MFCD18432122 | 152.193 | C9H12O2 | 97.000 | COc1c(C)cc(O)cc1C | 1g | 457921793
BIOHIPPO h/m P53-sh-BSD
h/m P53-sh-BSD shRNA lentiviral vector expressing with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated human P53 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human tumor suppressor protein p53 (P53/TP53) The shRNA has been validated to meet or exceed 70% P53 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Sigma Aldrich Fine Chemicals Biosciences Phosphatase substrate 40 m
Human phosphatase-substrate networks are mapped based on the literature and protein-protein interaction (PPI) database. Based on gene expression data the possible network of phosphatase-substrate-kinase is predicted.
Medchemexpress LLC Moracin M | 56317-21-6 | 99.0% | 1 ML
Moracin M is a phenolic endogenous metabolite supplied for research and analytical applications (CAS 56317-21-6). It has molecular formula C14H10O4 and molecular weight 242.23 g/mol. Manufacturer documentation provides DMSO solubility guidance and example volumes for preparing 1 mM, 5 mM, and 10 mM stock solutions.
- Analytical standard for research and analytical applications.
- Reported phosphodiesterase inhibitory activity.
- Molecular formula C14H10O4.
- Molecular weight 242.23 g/mol.
- Manufacturer provides DMSO solubility guidance and example volumes to prepare 1 mM, 5 mM, and 10 mM stocks.
- Supplied as a solid with solution preparation guidance.
Apexbio Technology LLC EZ Cap Mouse GM-CSF mRNA (m1Ψ) 100ug (1mg/mL)
GM-CSF mRNA encodes Granulocyte-Macrophage Colony-Stimulating Factor (CSF) produced by T cells macrophages endothelial cells and fibroblasts It stimulates the differentiation of hematopoietic stem cells in bone marrow into granulocytes and macrophages thereby enhancing the body s immune response capability GM-CSF not only promotes leukocyte production but also enhances their functions such as improving phagocytosis and antigen presentation abilities Clinically GM-CSF is used to treat certain types of leukopenia and serves as an adjuvant in cancer immunotherapy EZ Cap Mouse GM-CSF mRNA (m1 ) is provided at 1 mg/mL It expresses mouse-derived GM-CSF cytokine It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Medchemexpress LLC Glyoxalase I (GLO1) protein, mouse (His-tag) | >95.0% | 1 MG
Recombinant mouse Glyoxalase I (GLO1) is supplied as an N-terminal 6xHis-tagged protein expressed in Escherichia coli and lyophilized for stability. It catalyzes the conversion of hemithioacetal to S-lactoylglutathione and is suitable for biochemical assays and cellular studies involving methylglyoxal detoxification.
- Species: Mouse
- Expression system: Escherichia coli
- Tag: N-terminal 6xHis
- Purity: >95%
- Formulation: lyophilized from 20 mM PB, 150 mM NaCl, pH 7.4
- Molecular weight: approximately 25 kDa and 48 kDa
- Storage: store at -20 °C; freeze aliquots at -80 °C for long term
- Available size: 1 mg
BIOHIPPO h/m SREBP2-sh-RFP-Puro
h/m SREBP2-sh-RFP-Puro shRNA lentiviral vector expressing RFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m SREBP2 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse sterol regulatory element binding transcription factor 2 (SREBP2/SREBF2) The shRNA has been validated to meet or exceed 70% knockdown of SREBP2 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO TetOn h/m P53-sh-BSD
TetOn h/m P53-sh-BSD shRNA lentiviral vector expressing with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated human P53 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human tumor suppressor protein p53 (P53/TP53) The shRNA has been validated to meet or exceed 70% P53 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC M-PEG2-acid | 149577-05-9 | 5 G
m-PEG2-acid is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) are molecules that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins. These molecules typically consist of two different ligands connected by a linker, where one ligand binds to an E3 ubiquitin ligase and the other binds to the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system for selective degradation of target proteins
- Intended for research use only
Apexbio Technology LLC EZ Cap Mouse CD80 mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Mouse CD80 mRNA encodes CD80P Binding to CD28 and CTLA-4 receptors on T cells CD80 modulates T-cell activation and inhibition CD80 interacting with CD28 promotes T-cell activation and proliferation enhancing immune responses Its binding to CTLA-4 provides inhibitory signals maintaining immune tolerance and preventing excessive immune reactions CD80 have emerged as therapeutic targets in various immunotherapies such as treatments for autoimmune diseases transplantation rejection and cancer immunotherapy EZ Cap Mouse CD80 mRNA (m1 HA tag) is provided at 1 mg/mL and expresses mouse CD86 cytokine fused with an HA tag facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo