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Filtered Search Results
eMolecules EMOLECULES INC
5000482160 IODOCHLOROMETHANE 25G
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eMolecules EMOLECULES INC
5000482072 POTASSIUM BISTRIMETHYLSILY 5G
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eMolecules EMOLECULES INC
5000482043 DIETHYLAMINODIFLUOROSULFO 5G
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Medchemexpress LLC (S)-(-)-tert-Butylsulfinamide | 343338-28-3 | 99.9% | 121.20 | 25 G
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(S)-(-)-tert-Butylsulfinamide is a compound featuring a chiral sulfur atom. It is utilized in the synthesis of other compounds and serves as a chiral auxiliary in the asymmetric synthesis of organic compounds.
- Contains a chiral sulfur atom
- Used in the synthesis of other compounds
- Acts as a chiral auxiliary in asymmetric synthesis of organic compounds
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Medchemexpress LLC Pyrazoloadenine | 2380-63-4 | 100.0% | 135.13 | 25 G
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Pyrazoloadenine is a potent inhibitor of the RET (REarranged during Transfection) lung cancer oncoprotein, demonstrating anticancer activity. It is intended for research use only and not for sale to patients.
- Potent RET lung cancer oncoprotein inhibitor.
- Shows anticancer activity.
- Inhibits a wide range of protein kinases, including BTK, CDK1/2, Src kinase, and RIPK1.
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Medchemexpress LLC NGM-621 1mg | 1mg
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NGM-621 is a CHO-expressed human antibody that targets Complement C3 NGM-621 contains a huIgG1 heavy chain and a hu light chain with a predicted molecular weight (MW) of 149 04 kDa The isotype control for NGM-621 can be referenced as Human IgG1 kappa Isotype Control (HY-P99001)
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eMolecules EMOLECULES INC
5000488573 3 3-DIFLUOROAZETIDINE HYDRO 5G
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eMolecules EMOLECULES INC
5000488702 2-HYDROXYMETHYLPROPANE- 100G
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eMolecules EMOLECULES INC
5000488604 2-CHLOROISONICOTINALDEHYD 100G
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eMolecules EMOLECULES INC
5000488706 POTASSIUM VINYLTRIFLUOROBO 25G
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eMolecules EMOLECULES INC
5000488871 SILVER TRIFLUOROMETHANESUL 25G
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Ambeed Methyl 6chloropyridazine4carbo
Methyl 6-chloropyridazine-4-carboxylate, 1093860-48-0, 98%
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Medchemexpress LLC ML-00253764 hydrochloride | 1706524-94-8 | 99.3% | 413.71 | 1 MG
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ML-00253764 hydrochloride is a brain penetrant, nonpeptidic melanocortin receptor 4 (MC4R) antagonist with Ki and IC50 values of 0.16 μM and 0.103 μM, respectively. It is capable of crossing the blood-brain barrier.
- Target: melanocortin receptor 4 (MC4R) antagonist.
- Brain penetrant: can cross the blood-brain barrier.
- In vitro activity: displaces NDP-α-MSH binding with a mean IC50 of 0.32 μM for hMC4-R, 0.81 μM for hMC3-R, and 2.12 μM for hMC5-R. At 100 μM, it decreases cAMP production induced by [NLE4,D-Phe7]-α-melanocyte stimulating hormone ([NDP]-α-MSH) by 20% in MC4R-expressing HEK293 cell membranes, but shows no effect on cAMP levels in MC3R- or MC5R-expressing membranes.
- In vivo activity: in CT-26 tumor-bearing BALB/c mice, subcutaneous injection (3, 10, or 30 mg/kg; once daily) showed protection against tumor-induced body weight loss.
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Medchemexpress LLC Dicyclomine hydrochloride | 67-92-5 | 98.1% | 100 MG
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Dicyclomine hydrochloride is a potent, orally active antagonist of muscarinic cholinergic receptors, showing high affinity for M1 (Ki=5.1 nM) and M2 (Ki=54.6 nM) subtypes. It acts as an antispasmodic agent, relieving smooth muscle spasms in the gastrointestinal tract in vivo.
- An orally active antagonist of muscarinic cholinergic receptors.
- Demonstrates high affinity for both M1 and M2 muscarinic receptor subtypes (Ki values: M1=5.1 nM, M2=54.6 nM).
- Functions as an antispasmodic agent.
- Relieves smooth muscle spasms in the gastrointestinal tract in vivo.
- May exacerbate cognitive impairments and lead to behavioral impairments in spatial tasks in animal models.
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Ambeed 1HInden2 3H one
1H-Inden-2(3H)-one, 615-13-4, 98%
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