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Filtered Search Results
Medchemexpress LLC Opiranserin hydrochloride (VVZ-149 hydrochloride) | 1440796-75-7 | 99.6% | 430.97 | 50 MG
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Opiranserin hydrochloride (VVZ-149 hydrochloride) is a non-opioid and non-NSAID analgesic candidate. It functions as a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50 values of 0.86 and 1.3 μM, respectively. Additionally, it demonstrates antagonistic activity on rP2X3 (IC50=0.87 μM). It is being developed as an injectable agent for the treatment of postoperative pain and is intended for research use only.
- Functions as dual antagonist of GlyT2 and 5HT2A
- Demonstrates antagonistic activity on rP2X3
- Intended for research use only
- Developed as an injectable agent for postoperative pain
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Medchemexpress LLC Alvespimycin hydrochloride | 467214-21-7 | 98.8% | 5 MG
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Alvespimycin hydrochloride is a small-molecule Hsp90 inhibitor used for biochemical and cell-based research. It is supplied as the hydrochloride salt to improve solubility and has reported activity at low nanomolar concentrations.
- Potent Hsp90 inhibitor; EC50 62 ± 29 nM.
- Hydrochloride salt for enhanced solubility.
- Molecular weight 653.21 g/mol; formula C32H49ClN4O8.
- Available in small pack sizes suitable for research-scale use.
- Purity reported as 98.8% (HPLC).
- Suitable for biochemical and cell-based assays.
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Medchemexpress LLC ML-00253764 hydrochloride | 1706524-94-8 | 99.3% | 413.71 | 1 MG
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ML-00253764 hydrochloride is a brain penetrant, nonpeptidic melanocortin receptor 4 (MC4R) antagonist with Ki and IC50 values of 0.16 μM and 0.103 μM, respectively. It is capable of crossing the blood-brain barrier.
- Target: melanocortin receptor 4 (MC4R) antagonist.
- Brain penetrant: can cross the blood-brain barrier.
- In vitro activity: displaces NDP-α-MSH binding with a mean IC50 of 0.32 μM for hMC4-R, 0.81 μM for hMC3-R, and 2.12 μM for hMC5-R. At 100 μM, it decreases cAMP production induced by [NLE4,D-Phe7]-α-melanocyte stimulating hormone ([NDP]-α-MSH) by 20% in MC4R-expressing HEK293 cell membranes, but shows no effect on cAMP levels in MC3R- or MC5R-expressing membranes.
- In vivo activity: in CT-26 tumor-bearing BALB/c mice, subcutaneous injection (3, 10, or 30 mg/kg; once daily) showed protection against tumor-induced body weight loss.
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Ambeed 2 4 Bromomethyl phenyl 4 4 5 5
2-(4-(Bromomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 138500-85-3, 97%
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Medchemexpress LLC Martinostat hydrochloride | 1629052-58-9 | 99.0% | 390.95 | C22H31ClN2O2 | 10 MG
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Martinostat hydrochloride is a histone deacetylase (HDAC) inhibitor that can be labeled with radionuclides for quantitative in vivo imaging of HDACs in the central nervous system and major peripheral organs.
- Histone deacetylase inhibitor suitable for imaging applications.
- Can be labeled with radionuclides for quantitative in vivo imaging.
- High purity (99.01%).
- Available as solid (5-500 mg; larger sizes by quote) and as 10 mM solution in DMSO.
- Storage: 4°C sealed; in solvent store at -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Dl-3-phenylserine hydrate | 313222-82-1 | 100.0% | 199.20 | C9H13NO4 | 10 G
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DL-3-Phenylserine hydrate is the hydrated form of DL-3-phenylserine, a serine derivative supplied for laboratory research use. It is an off-white to light yellow solid with properties suitable for biochemical and synthetic chemistry applications; it is intended for research purposes only and not for human or animal use. Typical identifiers include CAS 313222-82-1, molecular formula C9H13NO4, and molecular weight 199.20 g/mol.
- High chemical purity suitable for research applications.
- Hydrated solid form compatible with aqueous experiments.
- Characterized by CAS number and molecular formula for unambiguous identification.
- Available in laboratory-scale pack sizes such as 5 G, 10 G, and 25 G.
- Stable at room temperature when stored as recommended.
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Medchemexpress LLC Pilocarpine hydrochloride | 54-71-7 | 99.98% | 5 G
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Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist. It is intended for research use only.
- Potent M3-type muscarinic acetylcholine receptor agonist
- Unstable in solutions, freshly prepared is recommended
- Suitable for laboratory centrifugation and storage
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Medchemexpress LLC 3-Acrylamidopropyl 10g
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(3-Acrylamidopropyl)trimethylammonium chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research
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Medchemexpress LLC Regorafenib hydrochloride | 835621-07-3 | MFCD22417053 | C21H16Cl2F4N4O3 | 10MG
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Regorafenib hydrochloride is the hydrochloride salt of regorafenib, a potent multi-target kinase inhibitor. Supplied as an analytical standard for research use, it inhibits VEGFR1/2/3, PDGFRβ, Kit, RET, and Raf-1 with low-nanomolar potency, and is intended for in vitro and analytical applications such as HPLC, GC, and MS.
- Multi-target kinase inhibitor active against VEGFR1/2/3, PDGFRβ, Kit, RET, and Raf-1.
- Low-nanomolar potency reported for key kinase targets.
- High purity analytical standard (99.6%).
- Intended for research and analytical applications, including HPLC, GC, and MS.
- Suitable for method development and quantitative assays.
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STA PHARMACEUTICAL US LLC Fmoc-(S)-2-amino-6,6,6-Triflurohexanoic acid | 1 g | CAS 2230472-61-2 | InChIKey RVXLFAQYYCBCAT-SFHVURJKSA-N
Fmoc-(S)-2-amino-6,6,6-Triflurohexanoic acid is a Amino Acid reagent (Subcategory: Unusual AA) sold by WuXi TIDES. Offered in 1 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 2230472-61-2
- MDL: No data
- InChIKey: RVXLFAQYYCBCAT-SFHVURJKSA-N
- Molecular Weight: 407.389
- Molecular Formula: C21H20F3NO4
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6,6,6-trifluorohexanoic acid
- SMILES: O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@H](C(O)=O)CCCC(F)(F)F
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Medchemexpress LLC Ctx-0294885 hydrochloride | 2319590-02-6 | 99.6% | 474.39 g/mol | C22H25Cl2N7O | 10 MG
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CTX-0294885 hydrochloride is a broad-spectrum kinase inhibitor used in biochemical and cellular research to profile kinase interactions and signaling pathways relevant to inflammation, diabetes, and cancer. It is supplied as a light yellow to yellow solid with high purity suitable for research applications.
- Broad-spectrum kinase inhibition for kinome profiling and target discovery
- High purity (99.6%) suitable for biochemical and cellular assays
- Chemical formula C22H25Cl2N7O; molecular weight 474.39 g/mol
- Light yellow to yellow solid appearance
- Storage: 4°C sealed and dry; if in solvent, store at -80°C (6 months) or -20°C (1 month)
- Supplied as a 10 MG research pack
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Medchemexpress LLC Vernakalant hydrochloride | 748810-28-8 | MFCD09833303 | 99.3% | C20H32ClNO4 | 10MG
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Vernakalant hydrochloride is a research chemical that acts as a mixed voltage- and frequency-dependent sodium channel blocker and an atria-preferred potassium channel blocker, used to investigate atrial electrophysiology and arrhythmia mechanisms. It is supplied in solid and DMSO solution formats and is characterized by defined molecular properties for in vitro studies.
- High purity (99.33%).
- Available as solid and 10 mM DMSO solution.
- Suitable for in vitro electrophysiology and pharmacology studies.
- Molecular formula C20H32ClNO4; molecular weight 385.93 g·mol⁻¹.
- For research use only; not for human or veterinary use.
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Ambeed 4 6Dichloro2methylsulfonylpyri
4,6-Dichloro-2-methylsulfonylpyrimidine, 4489-34-3, 98%
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Medchemexpress LLC CARM1-IN-3 dihydrochloride | 912970-67-3 | 98.8% | 481.46 | C24H34Cl2N4O2 | 10 MG
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CARM1-IN-3 dihydrochloride is a small-molecule inhibitor selective for co-activator associated arginine methyltransferase 1 (CARM1). Supplied as a white to off-white solid, it shows potent inhibition of CARM1 (IC50 = 0.07 μM) with minimal activity versus CARM3, and is intended for research use in biochemical and cellular assays. Store sealed and away from moisture; follow recommended cold storage for long-term stability.
- Potent and selective CARM1 inhibition (IC50 = 0.07 μM).
- High purity for reproducible experimental results (98.77%).
- White to off-white solid suitable for analytical and biological applications.
- Dihydrochloride salt form compatible with aqueous preparations.
- Recommended storage: sealed, away from moisture; in solvent -80°C (6 months), -20°C (1 month).
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Medchemexpress LLC Hsp90-IN-17 hydrochloride | 1253584-63-2 | 99.3% | 476.87 | C21H21ClN4O7 | 10 MG
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Hsp90-IN-17 hydrochloride is a small-molecule HSP90 inhibitor supplied as a hydrochloride salt for preclinical research. It is used as a tool compound to probe HSP90-dependent pathways in proliferative diseases such as cancer and in models of neurodegeneration. The material is provided with high reported purity and storage recommendations for maintaining stability.
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