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Filtered Search Results
Medchemexpress LLC Treprostinil sodium | 289480-64-4 | 99.55% | 412.49 | 1 ML
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Treprostinil (UT-15) sodium is a potent DP1 and EP2 agonist. It exhibits high affinity for the DP1, EP2, and IP receptors, with lower affinity for EP1, EP4, EP3, FP, and TP receptors. Activation of IP, DP1, and EP2 receptors can lead to vasodilation of human pulmonary arteries.
- Potent DP1 and EP2 agonist.
- High affinity for DP1, EP2, and IP receptors.
- Can lead to vasodilation of human pulmonary arteries.
- Inhibits the viability of cultured endothelial colony-forming cells.
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BIOHIPPO AAV-CAG-GACh2.0-WPRE-pA
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Recombinant adeno associated virus expressing gACh2.0 under the CAG promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Medchemexpress LLC Murexide (ammonium purpurate) | 3051-09-0 | MFCD00012777 | 98.0% | 284.19 g/mol | C8H8N6O6 | 25G
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Murexide (ammonium purpurate) is an analytical reagent used primarily as an indicator in complexometric titrations for determining water hardness and detecting certain metal ions. It is supplied as a solid powder with a typical purity of 98.0% and has the chemical formula C8H8N6O6 (MW 284.19 g/mol), making it suitable for laboratory and research analytical applications.
- Indicator for complexometric titrations to determine water hardness.
- Solid powder form suitable for analytical preparations.
- Typical purity 98.0%.
- Chemical formula C8H8N6O6; molecular weight 284.19 g/mol.
- Available in multiple gram pack sizes for laboratory use.
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Biotium Tyramides and Tyramide Signal Amplification Kits Fluorescence Microscopy Reactive CF Dyes Other Dyes Biotinylation Reagents TyraMax 405 450 1/EA
TyraMax Dyes are next-gen tyramide (TSA) dyes for spatial biology with colors from blue to near-IR named for their excitation/emission They are stable in amplification buffer with advantages in color selection brightness and photostability vs other TSA dyes 100X in DMSO 20 uL trial size
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Medchemexpress LLC Suberoyl bis-hydroxamic acid | 38937-66-5 | 95.0% | 204.22 | 10 MM 1 ML
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Suberoyl bis-hydroxamic acid | 38937-66-5 | 95.0% | 204.22 | 10 MM 1 ML
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Medchemexpress LLC E-Selectin/CD62E Mo 500ug
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E-Selectin/CD62E protein a cell-surface glycoprotein mediates the adhesion of blood neutrophils to cytokine-activated endothelium through interaction with SELPLG/PSGL1 It also potentially contributes to capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2 These multifaceted interactions highlight E-Selectin s role in cell adhesion and its potential influence on vascular development E-Selectin/CD62E Protein Mouse (HEK293 His) is the recombinant mouse-derived E-Selectin/CD62E protein expressed by HEK293 with C-His C-10 His labeled tag
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Cambridge Isotope Laboratories Dodecylphosphocholine (D38 98%) 0 1 mg
Dodecylphosphocholine (D38 98%) 0 1 mg
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Medchemexpress LLC Acridone | 578-95-0 | 195.22 | 100 G
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Acridone is an organic compound derived from the acridine skeleton, known for its diverse biological activities. It has been observed to possess antibacterial, antimalarial, antiviral, and anti-neoplastic properties. This versatile compound has also been shown to inhibit the proliferation of human breast cancer cells in vitro and to block the expression of ATP binding cassette subfamily G member 2 (ABCG2) at both mRNA and protein levels, highlighting its potential in various research applications.
- Organic compound based on the acridine skeleton.
- Exhibits antibacterial properties.
- Possesses antimalarial activity.
- Demonstrates antiviral effects.
- Shows anti-neoplastic activities.
- Inhibits proliferation of human breast cancer cells.
- Blocks expression of ATP binding cassette subfamily G member 2 (ABCG2).
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Medchemexpress LLC Withaphysalin E | 118985-24-3 | 482.57 | 500 UG
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Withaphysalin E is a natural product isolated from Physalis divericata, primarily used in the study of non-small cell lung cancer. This white to off-white solid has a molecular weight of 482.57 and a molecular formula of C28H34O7. It is classified as a steroid, originating from plants in the Solanaceae family.
- Isolated from Physalis divericata
- Used in the study of non-small cell lung cancer
- Solid appearance
- White to off-white color
- Molecular formula: C28H34O7
- Molecular weight: 482.57
- Classified under steroids
- Sourced from Solanaceae family plants
- Soluble in DMSO (15 mg/mL), requires ultrasonic and warming for in vitro use
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Medchemexpress LLC Ono-AE3-208 | 402473-54-5 | MFCD13184814 | >98.3% | C24H21FN2O3 | 1 ML
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ONO-AE3-208, also known as AE 3-208, is a selective and orally active EP4 receptor antagonist with a Ki of 1.3 nM. It demonstrates less potent effects on EP3, FP, and TP receptors. This compound is capable of suppressing cell invasion, migration, and metastasis of prostate cancer, showing dose-dependent inhibition of cell invasion and migration in vitro without affecting proliferation. In vivo studies indicate that ONO-AE3-208 suppresses the bone metastasis of PC3 cells in mice.
- Suppresses cell invasion, migration, and metastasis of prostate cancer
- Inhibits cell invasion and migration in a dose-dependent manner in vitro
- Does not affect cell proliferation in vitro
- Abolishes CTGF in the presence of the EET synthesis inhibitor MS-PPOH
- Blocks arachidonic acid (AA)-induced dilation of the attached Af-Art
- Suppresses bone metastasis of PC3 cells in mice
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Medchemexpress LLC FGF-21 Protein, Mouse (HEK293, His) | ≥ 95% | 20.8 kDa (predicted); 20-25 kDa (SDS-PAGE) | 1 MG
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FGF-21 Protein, Mouse (HEK293, His) influences glucose uptake in adipocytes by inducing SLC2A1/GLUT1 expression, particularly with KLB's presence. It plays a crucial role in systemic glucose homeostasis and insulin sensitivity, interacting directly with KLB through its C-terminus and engaging with FGFR4. The protein's molecular mechanisms involve a complex interplay, emphasizing its broad impact beyond localized effects. It is the recombinant mouse-derived FGF-21 protein, expressed by HEK293, with a C-6*His labeled tag.
- Influences glucose uptake in adipocytes by inducing SLC2A1/GLUT1 expression.
- Plays a crucial role in systemic glucose homeostasis and insulin sensitivity.
- Interacts directly with KLB through its C-terminus and engages with FGFR4.
- Recombinant mouse-derived protein.
- Expressed by HEK293.
- Features a C-6*His labeled tag.
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Medchemexpress LLC Nrf2 (69-84) | 1364173-77-2 | 95.25% | 1858.01 | 25 MG
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Nrf2 (69-84) is a peptide fragment of Nrf2 protein that contains the key ETGE motif, which is an important region for binding to the Kelch domain of Keap1 protein. It can be used to study the role of Nrf2 in the development and progression of diseases, especially in cancer, neurodegenerative diseases, and inflammatory diseases.
- Peptide fragment of Nrf2 protein
- Contains key ETGE motif for binding to Keap1 protein
- Suitable for studying Nrf2's role in cancer
- Useful for research into neurodegenerative diseases
- Applicable for inflammatory diseases research
- Powder storage: -80°C for 2 years, -20°C for 1 year
- Soluble in H2O at 9.09 mg/mL (4.89 mM)
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Cambridge Isotope Laboratories Parlar 69 (13C10 99%) 10 ug/mL in nonane 1 2 mL
Parlar 69 (13C10 99%) 10 ug/mL in nonane 1 2 mL
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Medchemexpress LLC IL-1RAcP/IL-1 R3 Mo 100ug | 100ug
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IL-1RAcP is a co-receptor for IL1RL2 IL1R1 and IL1RL1 in the IL-36 IL-1 and IL-33 signaling system respectively IL-1RAcP is an essential component of the IL-1 receptor and plays an essential role in the inflammatory process[1][2] IL-1RAcP/IL-1 R3 Protein Mouse (HEK293 Fc) is a recombinant mouse IL-1RAcP protein with an hFc tag at the C-terminus and is expressed in HEK293 cells
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Medchemexpress LLC Isovanillin | 621-59-0 | 99.99% | 152.15 | 500 G
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Isovanillin is identified as an aldehyde oxidase inhibitor and exhibits antispasmodic and antidiarrheal activities. It is not a substrate for aldehyde oxidase and is metabolized to isovanillic acid primarily by aldehyde dehydrogenase.
- Acts as an aldehyde oxidase inhibitor.
- Demonstrates relaxant effects on ileum contractions induced by 5-HT.
- Has antidiarrheal and anti-motility effects on the gastrointestinal tract.
- Potentially useful for research involving aldehyde oxidase inhibition.
- Offers a compound with known antispasmodic properties for relevant pharmacological studies.
- Provides a substance with documented antidiarrheal effects, suitable for gastrointestinal research.
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