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Filtered Search Results
Medchemexpress LLC XP-524 | 2344825-52-9 | 98.0% | 552.65 | 100 MG
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XP-524 is a potent BET and EP300 inhibitor that demonstrates significant tumoricidal activity in vivo. It prevents KRAS-induced neoplastic transformation and extends survival in aggressive pancreatic ductal adenocarcinoma (PDAC) mouse models. This compound also enhances self-peptide presentation and tumor recruitment of cytotoxic T lymphocytes, highlighting its potential for PDAC research.
- Potent BET and EP300 inhibitor
- Exhibits significant tumoricidal activity in vivo
- Prevents KRAS-induced neoplastic transformation
- Extends survival in aggressive pancreatic ductal adenocarcinoma (PDAC) mouse models
- Enhances self-peptide presentation and tumor recruitment of cytotoxic T lymphocytes
- Effective against fulvestrant-resistant and tamoxifen-resistant/sensitive MCF7/T47D cells
- Stable as powder for 3 years at -20°C
- Stable in solvent for 6 months at -80°C or 1 month at -20°C
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Medchemexpress LLC Estrogen receptor modulator 1 | 63676-22-2 | 99.9% | 242.29 | 25 MG
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Estrogen receptor modulator 1 (compound 18) is an orally active and selective estrogen receptor modulator (SERM), with a pIC50 of 0.46. It induces regression of Tamoxifen-resistant, hormone-independent xenograft tumors.
- Activation of estrogen response element in HeLa cells stably transfected with human Estrogen receptor beta (EC50: 17 nM).
- Activation of estrogen response element in HeLa cells stably transfected with human Estrogen receptor alpha (EC50: 50 nM).
- Agonist activity in transcriptional activation assay in SH-SY5Y neuroblastoma cells expressing Estrogen receptor beta (EC50: 10 nM).
- Inhibits colony formation at 100 nM for 10 days.
- Significantly inhibits growth of cells and induces apoptosis at 100 nM for 9 days.
- Induces regression of T47D:A18/PKCα tumors in vivo at 1.5 mg/animal daily for 2 weeks.
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![eMolecules 59255-94-6 | 2-Bromo-3-fluoronitrobenzene | Ambeed | MFCD07782080 | 219.997 | C6H3BrFNO2 | 95.000 | [O-][N+](=O)c1cccc(F)c1Br | 250mg | 552526764](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502426828.PNG-250.jpg)
eMolecules 59255-94-6 | 2-Bromo-3-fluoronitrobenzene | Ambeed | MFCD07782080 | 219.997 | C6H3BrFNO2 | 95.000 | [O-][N+](=O)c1cccc(F)c1Br | 250mg | 552526764
2-Bromo-3-fluoronitrobenzene | Ambeed | 59255-94-6 | MFCD07782080 | 219.997 | C6H3BrFNO2 | 95.000 | [O-][N+](=O)c1cccc(F)c1Br | 250mg | 552526764
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eMolecules 7521-41-7 | 2-Aminonicotinaldehyde | Ambeed | MFCD01830382 | 122.127 | C6H6N2O | 98.000 | Nc1ncccc1C=O | 100g | 552577154
2-Aminonicotinaldehyde | Ambeed | 7521-41-7 | MFCD01830382 | 122.127 | C6H6N2O | 98.000 | Nc1ncccc1C=O | 100g | 552577154
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Medchemexpress LLC Animal-Free CNTF Mo 10ug
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CNTF is a pluripotent neurotrophic factor belonging to the IL-6 cytokine family[1] CNTF could protect retinal cone and rod photoreceptors[2] CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons[3] Animal-Free CNTF Protein Mouse (His) is produced by E coli (M1-M198)with C-terminal His-tag This product is for cell culture use only
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![Alkali Scientific Timentin [Ticarcillin Disodium Salt/Potassium Clavulanate Mixture 15:1 Ratio], 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660512.jpg-250.jpg)
Alkali Scientific Timentin [Ticarcillin Disodium Salt/Potassium Clavulanate Mixture 15:1 Ratio], 25 G
Timentin (25g) is an effective antibiotic combining Ticarcillin Disodium Salt and Potassium Clavulanate in a 15:1 ratio. This formulation increases the effectiveness of Ticarcillin against resistant bacterial strains, especially those producing beta-lactamase. The combination therapy ensures broad-spectrum coverage against a variety of Gram-negative and Gram-positive organisms, including Pseudomonas aeruginosa and Klebsiella pneumoniae. This large-size packaging is ideal for high-volume clinical or laboratory use, especially when large amounts of the drug are required for treating severe infections or in high-throughput testing environments.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000302430 DESAMINOTYROSINE 100G
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eMolecules 32315-10-9 | Triphosgene | Chem-Impex | MFCD00062848 | 296.730 | C3Cl6O3 | 99.000 | ClC(Cl)(Cl)OC(=O)OC(Cl)(Cl)Cl | 5g | 213790489
Triphosgene | Chem-Impex | 32315-10-9 | MFCD00062848 | 296.730 | C3Cl6O3 | 99.000 | ClC(Cl)(Cl)OC(=O)OC(Cl)(Cl)Cl | 5g | 213790489
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![Aobchem 1-[3-(Propylthio)phenyl]ethanone | ≥95% | CAS 1342433-88-8 | C11H14OS | 250mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000925251.png-250.jpg)
Aobchem 1-[3-(Propylthio)phenyl]ethanone | ≥95% | CAS 1342433-88-8 | C11H14OS | 250mg
1-[3-(Propylthio)phenyl]ethanone | ≥95% | CAS 1342433-88-8 | C11H14OS | 250mg
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Aobchem Tetrahydro-3-[3-(1-methylethoxy)phenyl]-3-furanol | 95% | CAS 1542899-78-4 | C13H18O3 | 1g
Tetrahydro-3-[3-(1-methylethoxy)phenyl]-3-furanol | 95% | CAS 1542899-78-4 | C13H18O3 | 1g
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Aobchem 1-(3-(Cyclobutylmethoxy)phenyl)-2 2 2-trifluoroethanone | 95% | C13H13F3O2 | 500mg
1-(3-(Cyclobutylmethoxy)phenyl)-2 2 2-trifluoroethanone | 95% | C13H13F3O2 | 500mg
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Aobchem -Phenyl-3-dibenzofuranmethanol | 95% | CAS 1707567-89-2 | C19H14O2 | 1g
-Phenyl-3-dibenzofuranmethanol | 95% | CAS 1707567-89-2 | C19H14O2 | 1g
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Sigma Aldrich Fine Chemicals Biosciences 3 NN Dimethylmyristylammon25G
Zwitterionic detergent.
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Medchemexpress LLC Dicyclomine hydrochloride | 67-92-5 | 98.1% | 100 MG
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Dicyclomine hydrochloride is a potent, orally active antagonist of muscarinic cholinergic receptors, showing high affinity for M1 (Ki=5.1 nM) and M2 (Ki=54.6 nM) subtypes. It acts as an antispasmodic agent, relieving smooth muscle spasms in the gastrointestinal tract in vivo.
- An orally active antagonist of muscarinic cholinergic receptors.
- Demonstrates high affinity for both M1 and M2 muscarinic receptor subtypes (Ki values: M1=5.1 nM, M2=54.6 nM).
- Functions as an antispasmodic agent.
- Relieves smooth muscle spasms in the gastrointestinal tract in vivo.
- May exacerbate cognitive impairments and lead to behavioral impairments in spatial tasks in animal models.
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Aobchem (3-(Cyclobutylmethoxy)phenyl)(methyl)sulfane | 95% | C12H16OS | 250mg
(3-(Cyclobutylmethoxy)phenyl)(methyl)sulfane | 95% | C12H16OS | 250mg
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