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Filtered Search Results
Medchemexpress LLC HY-19706 1mg Medchemexpress, ARS-853 CAS:1629268-00-3 Purity:>98%
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Medchemexpress, HY-19706 1mg ARS-853 CAS:1629268-00-3 ARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5 μM. ARS-853 inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Valnivudine hydrochloride | 956483-03-7 | 98.99% | 534.04 | 1 ML
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FV-100 is a potent, selective, and orally active anti-varicella zoster virus agent. It is a proagent of CF-1743 and demonstrates very low toxicity *in vivo*.
- Potent anti-varicella zoster virus agent
- Selective activity
- Orally active
- Proagent of CF-1743
- Very low toxicity *in vivo*
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Medchemexpress LLC AR antagonist 1 | 1818885-54-9 | 99.0% | 1 ML
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AR antagonist 1 is a potent androgen receptor (AR) antagonist. This compound serves as a ligand for the target E3 ligase complex, demonstrating micromolar binding affinity. It is suitable for the design of highly potent and efficient PROTAC degraders, which utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Potent androgen receptor (AR) antagonist.
- Functions as a ligand for the E3 ligase complex.
- Exhibits micromolar binding affinity.
- Used in the synthesis of PROTACs.
- Enables the design of highly potent and efficient PROTAC degraders.
- Utilizes the ubiquitin-proteasome system for selective protein degradation.
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Medchemexpress LLC N,N-diethyl-4-(phenyl(piperidin-4-ylidene)methyl)benzamide hydrochloride | 209808-47-9 | >97.0% | 384.94 g/mol | C23H28N2O.HCl | 100 MG
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AR-M 1000390 hydrochloride is a non-peptidic, δ-selective opioid receptor agonist (hydrochloride salt) used for research into δ-opioid-mediated analgesia and receptor signaling. It is a brain-penetrant derivative of SNC-80 that shows potent agonist activity with low receptor internalization and diminished acute desensitization, making it useful for in vitro and in vivo pharmacology studies.
- Potent δ-opioid receptor agonist with EC50 ≈ 7.2 nM.
- Low receptor internalization compared with typical agonists.
- Reduces inflammation-induced hyperalgesia in animal models.
- Brain-penetrant following systemic administration.
- Hydrochloride salt, molecular weight 384.94 g/mol.
- Purity typically >97% by HPLC.
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Medchemexpress LLC Cycloguanil hydrochloride | 152-53-4 | 99.9% | 1 ML
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Cycloguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor. It blocks the folate metabolic pathway, affecting nucleotide synthesis and interfering with DNA replication. Cycloguanil inhibits DHFR in *Plasmodium*, making it useful in malaria research. It also potently inhibits DHFR in human cancer cells and blocks the transcriptional activity of STAT3, demonstrating anticancer activity.
- Inhibits dihydrofolate reductase (DHFR)
- Blocks folate metabolic pathway
- Interferes with DNA replication
- Useful in malaria research
- Exhibits anticancer activity
- Potently inhibits transcriptional activity of STAT3
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Medchemexpress LLC Icapamespib hydrochloride | 2267287-26-1 | 98.74% | 599.32 | 100 MG
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Icapamespib hydrochloride | 2267287-26-1 | 98.74% | 599.32 | 100 MG
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Medchemexpress LLC Ellipticine hydrochloride | 5081-48-1 | MFCD00050600 | 99.3% | 282.77 g·mol⁻1 | C17H15ClN2 | 10 MG
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Ellipticine hydrochloride is the hydrochloride salt of ellipticine, a polycyclic alkaloid used in research as a topoisomerase II inhibitor with antineoplastic activity. It is supplied as a light yellow solid with high reported purity for laboratory use only.
- Inhibits DNA topoisomerase II activity.
- High purity (99.34%).
- Light yellow solid physical form.
- Available in small research pack sizes, including 10 mg.
- Recommended storage: 4°C sealed; in solvent -80°C (6 months) and -20°C (1 month).
- For research use only; not for human or veterinary use.
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Medchemexpress LLC Avotaciclib hydrochloride | 1983983-41-0 | 99.75% | 317.73 | 100 MG
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Avotaciclib hydrochloride (Synonyms: BEY1107 hydrochloride) is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. It can inhibit the proliferation and induce apoptosis of tumor cells, making it suitable for cancer research, including pancreatic cancer and lung cancer.
- Orally active CDK1 inhibitor.
- Inhibits proliferation of tumor cells.
- Induces apoptosis in tumor cells.
- Applicable in research for various cancers like pancreatic cancer and lung cancer.
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Medchemexpress LLC Methoxamine hydrochloride | 61-16-5 | MFCD00058607 | 99.3% | 247.72 g/mol | C11H18ClNO3 | 10 MG
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Methoxamine hydrochloride is a selective α1-adrenergic receptor agonist used in vascular and receptor pharmacology research. Supplied as the hydrochloride salt in solid form, it is used to induce vasoconstriction and study α1-adrenergic signaling in tissue and cellular assays.
- Selective α1-adrenergic agonist for receptor and vascular studies.
- High purity suitable for research applications.
- Available as a solid powder for formulation or assay use.
- Soluble in polar solvents, compatible with common assay preparations.
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Medchemexpress LLC Icapamespib hydrochloride | 2267287-26-1 | 98.7% | C19H25Cl2IN6O2S | 10MG
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Icapamespib hydrochloride is the hydrochloride salt of icapamespib, a selective, orally active inhibitor of epichaperomes assembled by HSP90. It can cross the blood-brain barrier and promotes epichaperome disassembly by non-covalently binding HSP90, supporting studies of protein-protein interaction networks in neurodegenerative disease and oncology research.
- Selective inhibitor of epichaperomes assembled by HSP90.
- Orally active compound with slow dissociation kinetics.
- Crosses the blood-brain barrier for central nervous system research.
- Applicable to neurodegenerative disease and cancer research models.
- Supplied as a white to off-white solid with high purity for research use.
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eMolecules Medchem Express / 666-15 / 5mg / 446256484 / HY-101120 / / 1433286-70-4 / MFCD30182343 / 620.530 / C33H31Cl2N3O5
Medchem Express / 666-15 / 5mg / 446256484 / HY-101120 / / 1433286-70-4 / MFCD30182343 / 620.530 / C33H31Cl2N3O5
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Medchemexpress LLC Tiviciclovir hydrochloride | 00-00-0 | 275.69 g/mol | C9H14ClN5O3 | 100 MG
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Tiviciclovir hydrochloride is an antiviral guanosine analog that inhibits hepatitis B virus replication. Provided for research use only, the compound is supplied as the hydrochloride salt with formula C9H14ClN5O3 and a molecular weight of 275.69 g/mol. Solubility and storage recommendations follow the supplier datasheet.
- Antiviral guanosine analog with HBV inhibitory activity.
- Suitable for in vitro research applications (research use only).
- Soluble in DMSO at 100 mg/mL; may require ultrasonic treatment.
- Stable as a solid when stored sealed at 4°C.
- In solution, store at -80°C for up to 6 months or -20°C for up to 1 month.
- Includes molecular formula and molecular weight for reference.
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Medchemexpress LLC Sarpogrelate hydrochloride | 135159-51-2 | MFCD00887582 | >98.0% | 465.97 | C24H32ClNO6 | 100 MG
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Sarpogrelate hydrochloride is a research-grade selective antagonist of 5-HT2 receptors used in studies of vascular disease and thrombosis. It has published pKi values for 5-HT2A, 5-HT2B, and 5-HT2C receptors and is supplied as a high-purity hydrochloride salt for in vitro research.
- Selective 5-HT2 receptor antagonist with published pKi values.
- Suitable for research into vascular disease and thrombosis.
- High purity (>98.0% by HPLC), appropriate for analytical and biological studies.
- Molecular weight 465.97 g/mol.
- Available in multiple pack sizes, including 100 mg solid quantities.
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Medchemexpress LLC GSK 1562590 (hydrochloride) | 1003878-07-6 | 99.0% | 617.95 | 50 MG
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GSK 1562590 hydrochloride is a high affinity and selective antagonist of urotensin-II receptor (UT), with pKis of 9.14-9.66 for mammalian recombinant (mouse, rat, cat, monkey, human) and native UT.
- High affinity and selective antagonist of urotensin-II receptor (UT).
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Medchemexpress LLC Saxagliptin hydrochloride | 709031-78-7 | 99.7% | 351.87 | 5 MG
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Saxagliptin hydrochloride is a potent, selective, reversible, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. It has the potential for type 2 diabetes mellitus research.
- Potent, selective, reversible, competitive, and orally active DPP-4 inhibitor
- Induces β-cell proliferation
- Increases p-AKT and active β-catenin protein levels
- Prevents glucagon-like peptide-1 degradation
- Increases insulin secretion and decreases glucagon secretion
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