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Filtered Search Results
Aobchem AOBCHEM
5001013725 1-BROMO-2- CYCLOBUTYLMETHOXY B
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Aobchem 5-Bromo-8-ethoxyquinoline | ≥95% | CAS 101422-06-4 | C11H10BrNO | 1g
5-Bromo-8-ethoxyquinoline | ≥95% | CAS 101422-06-4 | C11H10BrNO | 1g
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Aobchem 1-Bromo-2-cyclopentylbenzene | ≥95% | CAS 59734-90-6 | C11H13Br | 250mg
1-Bromo-2-cyclopentylbenzene | ≥95% | CAS 59734-90-6 | C11H13Br | 250mg
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Aobchem 5-Bromo-1 3-dihydrobenzoimidazol-2-one | ≥95% | CAS 39513-26-3 | C7H5BrN2O | 10g
5-Bromo-1 3-dihydrobenzoimidazol-2-one | ≥95% | CAS 39513-26-3 | C7H5BrN2O | 10g
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Aobchem 2-(1-Adamantyl)-4-bromophenol | ≥95% | CAS 104224-68-2 | C16H19BrO | 10g
2-(1-Adamantyl)-4-bromophenol | ≥95% | CAS 104224-68-2 | C16H19BrO | 10g
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Aobchem 4-Bromo-2 6-diethylbenzaldehyde | ≥95% | CAS 1266114-84-4 | C11H13BrO | 250mg
4-Bromo-2 6-diethylbenzaldehyde | ≥95% | CAS 1266114-84-4 | C11H13BrO | 250mg
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Medchemexpress LLC SPOP-IN-6b dihydrochloride | 99.7% | 573.51 | 25 MG
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SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM. SPOP-IN-6b dihydrochloride shows IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells. SPOP-IN-6b (0.1-3.0 μM; 10 hours) dihydrochloride can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content.
- Potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM.
- Shows IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells.
- Can suppress SPOP activity and increase suppression cancer substrate protein PTEN and DUSP7 content.
- In vivo, it can slow down the growth of tumor by suppressing SPOP.
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Medchemexpress LLC Vupanorsen sodium | 2172852-12-7 | C296H414N86Na20O15P20S13 | 1 MG
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Vupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen (sodium) lowers triglycerides and atherogenic lipoproteins.
- Inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis
- Lowers triglycerides and atherogenic lipoproteins
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Medchemexpress LLC BRIVOLIGIDE SODIUM 1 mg
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BRIVOLIGIDE SODIUM 1MG
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Medchemexpress LLC PODOFILOX 100G
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PODOFILOX 100G
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Medchemexpress LLC LTGO-33 10MM 1ML
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LTGO-33 10MM 1ML
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Medchemexpress LLC CAPMATINIB DIHYDROC 500 mg
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CAPMATINIB DIHYDROC 500MG
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Medchemexpress LLC HPN-01 10MM 1ML
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HPN-01 10MM 1ML
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Selleck Chemical LLC BAY 41-2272
BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator
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Medchemexpress LLC N'-[3-[[5-bromo-2-[3-(pyrrolidine-1-carbonylamino)anilino]pyrimidin-4-yl]amino]propyl]-2,2-dimethylpropanediamide | 702676-93-5 | MFCD12922516 | 99.4% | 547.45 g·mol⁻1 | C23H31BrN8O3 | 1 MG
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BX-320 is a selective, ATP-competitive, orally active small-molecule inhibitor of PDK1 for preclinical research. It inhibits PDK1 with an IC50 of 30 nM, blocks PDK1/Akt signaling, induces apoptosis in tumor cells, and has demonstrated antiproliferative and antitumor activity in cell-based and animal models.
- Selective ATP-competitive PDK1 inhibitor (IC50 30 nM).
- Blocks PDK1/Akt signaling and induces apoptosis in tumor cells.
- Demonstrates antiproliferative activity in cell assays and efficacy in in vivo tumor models.
- Exhibits off-target activity against Chk1, c-Kit, KDR, PKA, CDK2, GSK3β, and PKC at micromolar concentrations.
- High purity (99.4%).
- Molecular weight 547.45 g·mol⁻1; formula C23H31BrN8O3.
- Store solid at -20°C; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
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