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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000382560 ZATEBRADINE HYDROCH 25MG
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eMolecules N-BROMOSUCCINIMIDE 100G
5000165601 N-BROMOSUCCINIMIDE 100G
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5000371352 NICE-01 10MM 1ML
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Apexbio Technology LLC 2,4,6-Triiodophenol 609-23-4 10mg
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2 4 6-Triiodophenol (CAS 609-23-4) is a small molecule inhibitor known to block the biosynthetic pathway of leukotriene B4 (LTB4) thereby modulating the production of pro-inflammatory mediators By targeting LTB4 synthesis it serves as a valuable tool for studying inflammatory processes and related signaling mechanisms Additionally this compound has been reported to induce apoptosis in murine blastocyst-stage cells making it relevant for investigations into early embryonic development embryotoxicity and the regulation of apoptotic pathways
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Medchemexpress LLC 2-piperidinone, 1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl] | 870843-42-8 | 97.0% | 419.49 | C25H26FN3O2 | 1 ML
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E 2012 is a small-molecule γ-secretase modulator used in preclinical research to reduce amyloid β-42 and to probe cholesterol biosynthesis via DHCR24 inhibition. Supplied for laboratory use as a concentrated solution in DMSO, it is intended for in vitro and related studies.
- Potent γ-secretase modulator activity.
- Reduces amyloid β-42 levels in cellular assays.
- Inhibits 3β-hydroxysterol Δ24-reductase (DHCR24).
- Available as a 10 mM solution in DMSO (1 mL) and as solid formats.
- High solubility in DMSO (~119 mM) with ultrasonic assistance.
- Manufacturer-reported purity approximately 97.0% and defined storage conditions.
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Apexbio Technology LLC Adiphenine HCl 50-42-0 10mM (in 1mL DMSO)
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Adiphenine hydrochloride (CAS 50-42-0) is a small molecule that functions as an inhibitor of nicotinic acetylcholine receptors By antagonizing these receptors Adiphenine hydrochloride disrupts cholinergic neurotransmission at autonomic ganglia and neuromuscular junctions This activity underlies its utility as an antispasmodic agent where it modulates smooth muscle contraction in physiological and pharmacological studies Adiphenine hydrochloride is utilized in biomedical research to investigate nicotinic receptor signaling pathways and to explore mechanisms underlying smooth muscle relaxation
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eMolecules BROMODIFLUOROMETHYLTRIME 25G
5000165224 BROMODIFLUOROMETHYLTRIME 25G
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eMolecules 3-BENZYLOXYCYCLOBUTANONE 10G
5000165242 3-BENZYLOXYCYCLOBUTANONE 10G
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![Medchemexpress LLC Acetamide, N-[2-(7-methoxy-1-naphthalenyl)ethyl]- (hydrochloride)(1:1) | 1176316-99-6 | 99.98% | 279.76 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000384298-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Acetamide, N-[2-(7-methoxy-1-naphthalenyl)ethyl]- (hydrochloride)(1:1) | 1176316-99-6 | 99.98% | 279.76 | 1 ML
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Agomelatine hydrochloride is a specific agonist of MT1 and MT2 receptors and a selective 5-HT2C receptor antagonist, primarily used for research. It demonstrates notable activity as a full agonist of MT1 and MT2 receptors and shows antioxidant properties in seizure models.
- Acts as a full agonist of MT1 and MT2 receptors
- Interacts with h5-HT2B receptors
- Demonstrates antioxidant activity in seizure models
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Apexbio Technology LLC Benzydamine HCl 132-69-4 10mM (in 1mL DMSO)
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Benzydamine hydrochloride (132-69-4) is a small-molecule inhibitor targeting cyclooxygenase (COX) enzymes It is designed to inhibit COX activity thereby reducing prostaglandin synthesis and regulating inflammatory pathways Benzydamine hydrochloride exerts its biological activity primarily through COX enzyme modulation and sodium channel blockade In cell-based assays benzydamine hydrochloride demonstrates prostaglandin production inhibition with an IC50 ranging from approximately 10 to 50 M depending on the experimental model Based on these pharmacological properties benzydamine hydrochloride holds research potential in investigating inflammatory pathways analgesic mechanisms and local anesthetic activity in vitro and in animal models
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Apexbio Technology LLC Eletriptan HBr 177834-92-3 10mM (in 1mL DMSO)
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Eletriptan hydrobromide (CAS 177834-92-3) is an orally bioavailable small molecule that acts as a selective agonist for the 5-hydroxytryptamine (serotonin) 5-HT1B and 5-HT1D receptors By activating these receptor subtypes eletriptan hydrobromide modulates cranial blood vessel tone and neuronal signaling implicated in migraine pathophysiology This compound is commonly utilized in preclinical and clinical research to investigate serotonergic modulation of neurovascular function and to explore therapeutic mechanisms relevant to migraine and related neurovascular disorders
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Medchemexpress LLC Olpasiran sodium | 2225856-03-9 | C490H610F11N164Na42O306P41S7 | 1 MG
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Olpasiran sodium is an N-acetyl galactosamine (GalNAc)-conjugated, hepatocyte-targeted siRNA. It directly inhibits LPA messenger RNA translation in hepatocytes and potently reduces Lp(a) concentration. It can be used for the research of cardiovascular disease, such as atherosclerosis.
- N-acetyl galactosamine (GalNAc)-conjugated, hepatocyte-targeted small interfering RNA.
- Potently reduces lipoprotein(a) concentration by directly inhibiting LPA messenger RNA translation.
- Demonstrated efficacy in silencing LPA reporter gene expression in human hepatocellular carcinoma cells.
- Achieves sustained and significant reductions in serum lipoprotein(a) levels in preclinical animal models.
- Potential application in cardiovascular disease research, specifically atherosclerosis.
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Medchemexpress LLC Hpk1-in-34 | 2380300-99-0 | C25H28N4O2S | 1 ML
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HPK1-IN-34 is an inhibitor of Hematopoietic progenitor kinase 1 (HPK1) with an IC50 of less than 100 nM. It is also a click chemistry reagent, featuring an Alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Azide groups. This product is intended for research use only.
- Inhibitor of HPK1 with an IC50 of less than 100 nM
- Click chemistry reagent
- Features an alkyne group for CuAAc reactions
- Light yellow to yellow solid
- Intended for research use only
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![Medchemexpress LLC 3-Piperidineacetic acid, 1-[5-[(cyclohexylamino)carbonyl]-6-(propylthio)-2-pyridinyl]-, (3S)- | 1024033-43-9 | 99.2% | 419.58 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000384103-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 3-Piperidineacetic acid, 1-[5-[(cyclohexylamino)carbonyl]-6-(propylthio)-2-pyridinyl]-, (3S)- | 1024033-43-9 | 99.2% | 419.58 | 25 MG
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AZD 4017 is a potent, selective 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) inhibitor, with an IC50 of 7 nM. It is for research use only.
- Potent, selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 7 nM.
- Displays excellent selectivity versus related enzymes such as 11-βHSD2, 17β-HSD1, 17β-HSD3 (all IC50 > 30 μM).
- Shows no measurable activity against glucocorticoid and mineralocorticoid receptors.
- Potent inhibitor of 11β-HSD1 activity in isolated human adipocytes from nondiabetic volunteers, with an IC50 of 0.002 μM.
- Appearance: solid.
- Color: light yellow to yellow.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380121 LEVOMEDETOMIDINE HY 25MG
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