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Filtered Search Results
Medchemexpress LLC Amantadine | 768-94-5 | 99.9% | 100 G
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Amantadine is an orally active and potent antiviral agent effective against influenza A viruses and coronaviruses. It inhibits various ion channels, including NMDA and M2, and shows anti-orthopoxvirus and anticancer activities. This compound is suitable for research applications related to Parkinson's disease, postoperative cognitive dysfunction, and COVID-19.
- Inhibits influenza A viruses and coronavirus ion channels
- Demonstrates anti-orthopoxvirus and anticancer activity
- Suitable for research on Parkinson's disease and COVID-19
- Inhibits SARS-CoV-2 replication in Vero E6 cells
- Markedly inhibits proliferation of HepG2 and SMMC 7721 cells
- Arrests cell cycle at G0/G1 phase and induces apoptosis
- Reduces cyclin D1, cyclin E, and CDK2 levels
- Increases Bax protein and mRNA levels while decreasing Bcl-2
- Inhibits surgery-induced neuroinflammation and learning impairment in rats
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Medchemexpress LLC SB-772077B (dihydrochloride) | 607373-46-6 | 99.33% | 415.28 | 25 MG
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SB-772077B dihydrochloride is an orally active aminofuran-based Rho kinase (ROCK) inhibitor. It has IC50 values of 5.6 nM for ROCK1 and 6 nM for ROCK2, reduces inflammatory cytokines, relaxes aortic rings, and lowers blood pressure. It is used in inflammatory disease research.
- Reduces LPS-induced inflammatory cytokines (TNF-α and IL-6) in primary human macrophages.
- Induces dose-dependent relaxation of Phenylephrine-precontracted rat aortic rings (IC50 of 39 nM).
- Significantly reduces blood pressure in spontaneously hypertensive and deoxycorticosterone acetate-induced hypertensive rats.
- Abolishes Angiotensin II-induced actin stress fiber formation in human primary aortic smooth muscle cells at 3 μM.
- Intended for research use only.
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Medchemexpress LLC Tempone (4-Oxo-Tempo) | 2896-70-0 | 99.1% | 25 G
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Tempone (4-Oxo-Tempo) is a stable water-soluble nitro radical used as a contrast agent for metabolic activity and hypoxic sensitivity in electron spin resonance spectroscopy, magnetic resonance imaging, and dynamic nuclear polarization.
- Reduces superoxide radicals by mimicking superoxide dismutase (SOD) activity
- Decreases the formation of hydroxyl radicals and peroxynitrites
- Applicable in studies of ischemia-reperfusion injury and acute renal failure
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Medchemexpress LLC Neutral Red (IND) | 553-24-2 | 96.3% | 100 G
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Neutral Red (IND) is an organic dye commonly used in biology and cytology laboratories. It can be used to stain living cells, secreted proteins and other molecular structures, and has a wide range of applications in cell imaging and staining. In addition, Neutral Red (IND) is widely used in industrial fields such as water treatment, food processing and paper manufacturing, for example as an indicator or colorant. Although the compound has no direct medical application, it has important application value in the fields of biology, chemistry and industry.
- Stains living cells, secreted proteins and other molecular structures.
- Wide range of applications in cell imaging and staining.
- Used in industrial fields such as water treatment, food processing and paper manufacturing as an indicator or colorant.
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Medchemexpress LLC Ilaprazole (sodium) | 172152-50-0 | 99.5% | 1 ML
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Ilaprazole sodium (IY-81149) is an orally active proton pump inhibitor. It irreversibly inhibits H+/K+-ATPase in a dose-dependent manner with an IC50 of 6 μM in rabbit parietal cell preparation. It is used for the research of gastric ulcers and is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor.
- Orally active proton pump inhibitor
- Irreversibly inhibits H+/K+-ATPase
- Potent TOPK inhibitor
- Used for the research of gastric ulcers
- Can be stored long-term under appropriate conditions
- Appearance: solid, white to off-white
- Molecular weight: 388.42
- Formula: C19H17N4NaO2S
- Shipping: room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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eMolecules 122927-84-8 | 3-Fluoro-4-iodophenol | MFCD12407087 | 1g
Medchem Express | Curdione | 10mg | 446274977 | HY-N0353 | 13657-68-6 | MFCD28977990 | 236.355 | C15H24O2
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Medchemexpress LLC Todralazine hydrochloride | 3778-76-5 | 99.9% | 5 MG
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Todralazine hydrochloride is an anti-hypertensive agent that acts as a β2AR blocker, possessing antioxidant and free radical scavenging activity. It is intended for research use only and not for sale to patients.
- Anti-hypertensive agent
- Acts as a β2AR blocker
- Possesses antioxidant activity
- Possesses free radical scavenging activity
- Intended for research use only
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Medchemexpress LLC Bucladesine sodium (Dibutyryl cAMP sodium salt) | 16980-89-5 | 99.4% | 5 G
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Bucladesine sodium salt, also known as Dibutyryl-cAMP sodium salt, is a stabilized cyclic AMP (cAMP) analog. It acts as a selective PKA activator and increases intracellular cAMP levels. This compound also functions as a phosphodiesterase (PDE) inhibitor, exhibiting anti-inflammatory activity and is utilized for its role in promoting wound healing.
- Acts as a stabilized cyclic AMP (cAMP) analog
- Functions as a selective PKA activator
- Increases intracellular cAMP levels
- Acts as a phosphodiesterase (PDE) inhibitor
- Exhibits anti-inflammatory activity
- Used for impaired wound healing
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eMolecules EMOLECULES INC
5000841497 S-N-FMOC-A-TETRAHYDRO-2 5G
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Ambeed Methyl 7bromo1Hindole5carboxyl
Methyl 7-bromo-1H-indole-5-carboxylate, 885523-35-3, 96%
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Ambeed Methyl 6chloropyridazine4carbo
Methyl 6-chloropyridazine-4-carboxylate, 1093860-48-0, 98%
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Ambeed Methyl 6chloropyridazine4carbo
Methyl 6-chloropyridazine-4-carboxylate, 1093860-48-0, 98%
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Ambeed 4 6Dichloro2methylsulfonylpyri
4,6-Dichloro-2-methylsulfonylpyrimidine, 4489-34-3, 98%
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eMolecules 1271-86-9 | (Dimethylaminomethyl)ferrocene | Ambeed245.147 | C13H19FeN | 98.000 | [Fe].C1C=CC=C1.CN(C)CC1=CC=CC1 | 100g | 572828933
(Dimethylaminomethyl)ferrocene | Ambeed | 1271-86-9245.147 | C13H19FeN | 98.000 | [Fe].C1C=CC=C1.CN(C)CC1=CC=CC1 | 100g | 572828933
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eMolecules 116435-77-9 | 2-amino-3-bromophenol | Pharmablock | MFCD08445676 | 188.024 | C6H6BrNO | 97.000 | Nc1c(O)cccc1Br | 10g | 784546463
2-amino-3-bromophenol | Pharmablock | 116435-77-9 | MFCD08445676 | 188.024 | C6H6BrNO | 97.000 | Nc1c(O)cccc1Br | 10g | 784546463
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