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RVX-208 (CAS 1044870-39-4) is a small-molecule inhibitor targeting BET (bromodomain and extra-terminal) proteins It is designed to selectively inhibit the binding of BET bromodomains to acetylated lysine residues thereby modulating transcriptional regulation RVX-208 exerts its biological activity primarily through competitive inhibition of the second bromodomain (BD2) of BET proteins In in vitro studies using human hepatic (HepG2) cells RVX-208 demonstrates BD2 inhibitory activity with an IC50 value of 0 51 M and lower affinity for BD1 (IC50 87 M) Based on these pharmacological properties RVX-208 holds research potential in lipid metabolism cholesterol efflux and atherosclerotic disease processes
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
RVX-208 (CAS 1044870-39-4) is a small-molecule inhibitor targeting BET (bromodomain and extra-terminal) proteins It is designed to selectively inhibit the binding of BET bromodomains to acetylated lysine residues thereby modulating transcriptional regulation RVX-208 exerts its biological activity primarily through competitive inhibition of the second bromodomain (BD2) of BET proteins In in vitro studies using human hepatic (HepG2) cells RVX-208 demonstrates BD2 inhibitory activity with an IC50 value of 0 51 M and lower affinity for BD1 (IC50 87 M) Based on these pharmacological properties RVX-208 holds research potential in lipid metabolism cholesterol efflux and atherosclerotic disease processes
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
L-pyrohomoglutamic acid is a non-proteinogenic amino acid used as a synthetic building block in medicinal chemistry and biochemical research. It is employed as an intermediate for preparing ligands targeting FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors, and is supplied as a purified powder for laboratory use.
High purity (~97%) suitable for research applications.
Used as a building block for FKBP and HDAC ligand synthesis.
Molecular formula C6H9NO3 and molecular weight 143.14 g·mol⁻¹.
Available in lab-scale pack sizes for synthetic and analytical workflows.
Provided with product documentation including COA and SDS for quality assurance.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(R)-BAY-85-8501 is the less active enantiomer of BAY-85-8501. BAY-85-8501 is a selective and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM. This product is for research use only.
High purity: 99.09%.
Appearance: White to off-white solid.
Molecular formula: C22H17F3N4O3S.
Soluble in DMSO (100 mg/mL).
Long-term storage recommended at -20°C for powder or -80°C for solutions.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(S)-(+)-2-Phenylglycine methyl ester hydrochloride is the S-enantiomer of 2-phenylglycine methyl ester presented as the hydrochloride salt. It is a chiral amino acid derivative used as a building block and intermediate in research chemistry, asymmetric synthesis, and preparation of optically active compounds. Supplied as a solid with documented purity and enantiomeric excess for research use.
High enantiomeric purity (100.0% ee) supporting stereospecific synthesis.
High chemical purity (99.9% by HPLC) for reliable analytical and synthetic use.
Molecular formula C9H12ClNO2 and molecular weight 201.65 g/mol.
White to off-white solid, convenient for handling and storage.
Stable under sealed refrigeration; COA and SDS available for traceability.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More