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Amitifadine hydrochloride is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It exhibits IC50 values of 12 nM for serotonin, 23 nM for norepinephrine, and 96 nM for dopamine in HEK 293 cells.
Functions as a triple monoamine reuptake inhibitor, affecting serotonin, norepinephrine, and dopamine reuptake.
High purity of 99.64%.
Soluble in DMSO at concentrations ≥ 100 mg/mL and in H2O at 50 mg/mL.
Studied in clinical trials for major depressive disorder.
Strictly for research purposes.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Amitifadine hydrochloride is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It exhibits IC50 values of 12 nM for serotonin, 23 nM for norepinephrine, and 96 nM for dopamine in HEK 293 cells. It is for research use only and not sold to patients.
Serotonin: 12 nM
Norepinephrine: 23 nM
Dopamine: 96 nM
Inhibition of [3H]dopamine uptake: 159 nM
Inhibition of [3H]serotonin uptake: 411 nM
Inhibition of [3H]noradrenaline uptake: 71 nM
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N-Phenylpivalamide is an organic small-molecule building block used in the synthesis of biologically active compounds. It is represented by the formula C11H15NO and has a reported CAS number 6625-74-7 and high reported purity.
small-molecule building block for synthesis of biologically active compounds.
chemical formula C11H15NO.
molecular weight approximately 177.24 g/mol.
reported high purity suitable for research applications.
available in small-scale packages for laboratory use.
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N-Phenylpivalamide (Pivalanilide) is a high-purity small-molecule building block used as an intermediate in organic synthesis and medicinal chemistry research. It is supplied as a white to off-white solid with long-term stability under recommended storage conditions.
High-purity building block suitable for synthesis applications.
White to off-white solid formulation for ease of handling.
CAS number 6625-74-7 for unambiguous identification.
Purity suitable for research use: 99.98% (typical).
Pack size available: 25 G.
Storage stable at room temperature for extended shelf life.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Amitifadine hydrochloride is a small-molecule serotonin-norepinephrine-dopamine reuptake inhibitor supplied as a solid research reagent for in vitro and preclinical studies. It is intended for laboratory research use only.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More