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Filtered Search Results
Apexbio Technology LLC AVE 0991 sodium salt 306288-04-0 50mg
AVE 0991 sodium salt (CAS 306288-04-0) is a synthetic non-peptide agonist of the angiotensin-(1-7) receptor Mas Acting as a functional mimic of angiotensin-(1-7) AVE 0991 competitively binds to endothelial cell membranes with an IC50 of 21 35 nM in bovine aortic endothelial cells In vitro treatment with AVE 0991 promotes nitric oxide release to levels significantly greater than angiotensin-(1-7) In vivo AVE 0991 reduces urine volume and increases urine osmolality in mice effects reversed by angiotensin II antagonists indicating receptor specificity It also inhibits atherogenesis in ApoE knockout mice supporting its application in cardiovascular and renal research
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TARGETMOL CHEMICALS INC NSC-87877 DISODIUM 25MG
502693753 NSC-87877 DISODIUM 25MG
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Medchemexpress LLC Suramin sodium salt | 129-46-4 | 100.0% | 25 MG
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Suramin sodium salt is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor. It also acts as a potent inhibitor of sirtuins (SirT1, SirT2, and SirT5) and a competitive inhibitor of reverse transcriptase (DNA topoisomerase II). Additionally, this agent is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor, efficiently inhibits IP5K, and functions as an antiparasitic, anti-neoplastic, and anti-angiogenic agent, intended for research use only.
- Reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor.
- Potent inhibitor of sirtuins (SirT1, SirT2, and SirT5).
- Competitive inhibitor of reverse transcriptase (DNA topoisomerase II).
- Potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor.
- Efficiently inhibits IP5K.
- Acts as an antiparasitic, anti-neoplastic, and anti-angiogenic agent.
- Intended for research use only.
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eMolecules 139-89-9 | Ambeed | Sodium 22-((2-((carboxylatomethyl)(2-hydroxyethyl)amino)ethyl)azanediyl)diacetate | 1000g | 632809015 | A1455022 | MFCD00043341 | 344.206 | C10H15N2Na3O7
Medchem Express | (RR)-GSK321 | 5mg | 713706082 | HY-128888 | 1816272-19-1 | 501.562 | C28H28FN5O3
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Selleck Chemical LLC Etomoxir sodium salt
Etomoxir sodium salt ((R)-( )-Etomoxir sodium salt) is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane Etomoxir enhances palmitate-induced cell apoptosis
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Apexbio Technology LLC Pamoic acid disodium salt,50mg CAS# 6640-22-8
Pamoic acid disodium salt, a supposedly inactive component in many formulations of drugs used to modulate release, is a potent agonist of the orphan receptor GPR35. GPR35 is a class A, rhodopsin-like G protein-coupled receptor (GPCR), strongly expressed in the lower intestine and colon, dorsal root ganglia, as well as a variety of immune cells including monocytes and dendritic cells. Targeting GPR35 provides potential therapeutic opportunities in a range of conditions, such as inflammation, pain and cancer. Other sizes are also available. Please inqury us for quote.
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eMolecules 25102-12-9 | Medchem Express | EDTA (dipotassium dihydrate) | 50g | 791206497 | HY-D0836 | 404.455 | C10H18K2N2O10
Medchem Express | Cholesterol-d6 | 1mg | 724442439 | HY-N0322S1 | 60816-17-3 | MFCD00201281 | 392.701 | C27H46O
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eMolecules 13429-27-1 | Potassiummyristate | Ambeed | MFCD00152765 | 266.466 | C14H27KO2 | 95.000 | [K+].CCCCCCCCCCCCCC([O-])=O | 5g | 714085493
Potassiummyristate | Ambeed | 13429-27-1 | MFCD00152765 | 266.466 | C14H27KO2 | 95.000 | [K+].CCCCCCCCCCCCCC([O-])=O | 5g | 714085493
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Apexbio Technology LLC Simvastatin (sodium salt)(Synonyms: Simvastatin sodium, Simvastatin sodium salt, Sodium simvastatin, Synvinolin sodium), 5mg, CAS: 101314-97-0.
Simvastatin (sodium salt) (CAS 101314-97-0) is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase a critical enzyme controlling the rate-limiting step in cholesterol biosynthesis It binds with high affinity to HMG-CoA reductase exhibiting a Ki of approximately 0 12 nM In hepatocyte-derived Hep G2 cells simvastatin demonstrated potent suppression of cholesterol biosynthesis reducing the incorporation of radiolabeled acetate into sterols (IC50 15 nM) Animal studies with orally administered simvastatin indicated marked reduction in plasma cholesterol levels validating its utility in experimental models exploring cholesterol regulation and lipid metabolism
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Medchemexpress LLC L 012 sodium salt | 143556-24-5 | 99.9% | 310.67 | 1 MG
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L 012 sodium salt is a luminal-based chemiluminescent probe that can detect NADPH oxidase (Nox)-derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS)).
- Detects NADPH oxidase (Nox)-derived superoxide and nitrogen species.
- Identifies reactive oxygen species (ROS) and reactive nitrogen species (RNS).
- Suitable for research applications.
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Apexbio Technology LLC CX-4945 sodium salt 1309357-15-0 10mg
CX-4945 sodium salt (Silmitasertib sodium salt CAS 1309357-15-0) is a potent and selective inhibitor of casein kinase 2 (CK2) effectively targeting both the CK2 and CK2 catalytic subunits By inhibiting CK2 activity CX-4945 disrupts signaling pathways involved in cell cycle progression transcriptional regulation and cell survival The compound exhibits oral bioavailability and is widely utilized in research focused on tumor biology mechanistic studies of signaling cascades and the functional characterization of protein kinases
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eMolecules 18746-63-9 | Ammonium hexachlororuthenate(IV), 99% | Strem Chemicals | MFCD00015962 | 349.850 | Cl6H8N2Ru | 99.000 | [NH4+].[NH4+].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru+4] | 1g | 321338399
Ammonium hexachlororuthenate(IV), 99% | Strem Chemicals | 18746-63-9 | MFCD00015962 | 349.850 | Cl6H8N2Ru | 99.000 | [NH4+].[NH4+].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru+4] | 1g | 321338399
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Apexbio Technology LLC PHOSPHO. DISODIUM SALT 5G
PHOSPHO. DISODIUM SALT 5G APEXBIO TECHNOLOGIES
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Medchemexpress LLC DIDS sodium salt | 67483-13-0 | 99.1% | 500 MG
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DIDS sodium salt (MDL101114ZA) is a dual inhibitor of ABCA1 and VDAC1. It also inhibits RAD51, preventing RAD51-mediated homologous pairing and strand exchange reactions. DIDS inhibits anion exchange and binding to red blood cell membranes, and suppresses the activation of caspase-3 and -9. It is suitable for cancer research.
- Dual inhibitor of ABCA1 and VDAC1.
- Inhibits RAD51, preventing homologous pairing and strand exchange.
- Inhibits anion exchange and binding to red blood cell membranes.
- Inhibits caspase-3 and -9 activation.
- Used in cancer research.
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Alkali Scientific X GlcA Sodium Salt [5 Bromo 4 chloro 3 indolyl β D glucuronic acid, sodium salt trihydrate], 250 Mg
X GlcA Sodium Salt [5 Bromo 4 Chloro 3 indolyl β-D-glucuronic acid, sodium salt trihydrate], 250 mg is a chromogenic substrate for detecting β-glucuronidase activity in microorganisms and biochemical assays. The substrate is hydrolyzed by the enzyme, producing a blue-colored product, which can be easily quantified spectrophotometrically. X GlcA Sodium Salt is commonly used in microbiology and molecular biology to identify microorganisms capable of hydrolyzing glucuronic acid. It is an essential reagent for enzyme activity assays, microbial diagnostics, and genetic screening studies where β-glucuronidase activity is a key marker for metabolic or enzymatic research.
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