Dicarboxylic acids and derivatives
Apexbio Technology LLC GlyH-101 328541-79-3 50mg
GlyH-101 (CAS 328541-79-3) is a cell-permeable glycinyl hydrazone derivative that acts as a selective inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel exhibiting a Ki of 1 4 M By blocking CFTR-mediated chloride transport GlyH-101 serves as a valuable tool for investigating CFTR function in epithelial physiology and pathophysiology as well as for studying mechanisms underlying cystic fibrosis and related disorders involving chloride ion dysregulation
Apexbio Technology LLC AS 101 106566-58-9 50mg
AS 101 (CAS 106566-58-9) chemically known as ammonium trichloro(dioxoethylene-O O -)tellurate is a non-toxic immunomodulatory small molecule that acts primarily by inhibiting interleukin-10 (IL-10) signaling In cell-based studies AS 101 reduces IL-10 production and suppresses mesangial cell proliferation in a dose-dependent manner It has been shown to decrease tyrosine phosphorylation and nuclear translocation of STAT3 correlating with inhibition of IL-10 activity AS 101 stimulates IL-2 secretion and enhances immune cell function in both human and murine models In animal studies systemic administration confers bone marrow-sparing effects during chemotherapy mitigates alopecia enhances survival in sepsis models and modulates cytokine production These properties support its utility in investigating immune regulation and potential therapeutic interventions targeting cytokine-mediated pathologies
Medchemexpress LLC AVN-101 hydrochlorid 25mg | 1061354-48-0 | 340.89 | C21H25ClN2 | 25 MG
AVN-101 hydrochloride is the hydrochloride salt of a brain-penetrant small molecule antagonist of serotonin (5-HT) receptors, supplied for preclinical and in-vitro research. It is provided as a solid with reported high purity for analytical and biological assays.
- Potent antagonist of 5-HT receptor subtypes (5-HT7, 5-HT6, 5-HT2A, 5-HT2C).
- High purity: 99.59%.
- Molecular formula C21H25ClN2; molecular weight 340.89.
- Available in small research pack sizes, including 25 MG.
- Provided as hydrochloride salt to improve solubility for assay preparation.
- For research use only; not for human or veterinary use.
![Medchemexpress LLC Tetradecanoic acid, 2,3-bis[(1-oxododecyl)oxy]propyl ester | 60175-30-6 | MFCD00063570 | 98.0% | 667.05 g/mol | C41H78O6 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000288249.png-250.jpg)
Medchemexpress LLC Tetradecanoic acid, 2,3-bis[(1-oxododecyl)oxy]propyl ester | 60175-30-6 | MFCD00063570 | 98.0% | 667.05 g/mol | C41H78O6 | 10 MG
1,2-Dilauroyl-3-myristoyl-rac-glycerol is a medium-chain triacylglycerol used as a research reagent and an intermediate for synthesizing functional edible oils and related lipid derivatives. It is typically supplied in small, research-scale quantities for laboratory studies.
- Medium-chain triacylglycerol suitable for lipid synthesis and formulation.
- High purity (98.0%) suitable for research applications.
- Chemical formula C41H78O6; molecular weight 667.05 g/mol.
- Appearance: white to off-white oil.
- Provided in small research-scale quantities (e.g., 10 mg).
Medchemexpress LLC Lauroyl-L-carnitine (chloride) | 6919-91-1 | 98.1% | 50 MG
Lauroyl-L-carnitine chloride is an orally active metabolite that exhibits anti-inflammatory effects and improves systemic and local phenotypes in TNBS mice. It significantly reverses the decrease in its target gene IL-10 and alleviates Crohn's-like colitis.
- Orally active metabolite
- Reverses decrease in target gene IL-10
- Exhibits anti-inflammatory effects
- Improves systemic and local phenotypes in TNBS mice
- Alleviates Crohn's-like colitis
Medchemexpress LLC Sodium lauroyl glutamate | 29923-31-7 | 95.8% | 1 G
Sodium lauroyl glutamate is an anionic amino acid surfactant used primarily in cleaning products. It is considered a mild surfactant with low irritation to nude mouse skin, exhibiting a pH value of 5.41. It also has potential for irritant contact dermatitis and possible anti-irritating effects in surfactant mixtures on human skin.
- Anionic amino acid surfactant
- Mild surfactant properties
- Ideal for cleaning product formulations
- Low irritation potential
- pH value of 5.41
Medchemexpress LLC Lauroyl-L-carnitine (chloride) | 6919-91-1 | 98.1% | 100 MG
Lauroyl-L-carnitine chloride is an orally active metabolite. It significantly reverses the decrease in its target gene IL-10 and alleviates Crohn's-like colitis. This compound exhibits anti-inflammatory effects and improves both systemic and local phenotypes in TNBS mice.
- Orally active metabolite
- Significantly reverses decrease in IL-10
- Alleviates Crohn's-like colitis
- Exhibits anti-inflammatory effects
- Improves systemic and local phenotypes in TNBS mice
- For research use only
Medchemexpress LLC Sodium lauroyl glutamate | 29923-31-7 | 95.8% | 100 MG
Sodium lauroyl glutamate is an anionic amino acid surfactant. It has the potential for irritant contact dermatitis and possible anti-irritating potential in a surfactant mixture on human skin. It is primarily used in cleaning products and has been shown to exhibit low irritation to nude mouse skin at 1% w/w for 1 hour. This product is for research use only and not sold to patients.
- Anionic amino acid surfactant.
- Low irritation to nude mouse skin at 1% w/w for 1 hour.
- Primarily used in cleaning products.
- Mild surfactant with a pH value of 5.41.
- For research use only.
TARGETMOL CHEMICALS INC MG-101 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins. purity: 98%
eMolecules 60372-77-2 | Ethyl Lauroyl Arginate Hydrochloride | ChemScene421.020 | C20H41ClN4O3 | 97.000 | Cl.CCCCCCCCCCCC(=O)NC(CCCNC(N)=N)C(=O)OCC | 25g | 632288177
Ethyl Lauroyl Arginate Hydrochloride | ChemScene | 60372-77-2421.020 | C20H41ClN4O3 | 97.000 | Cl.CCCCCCCCCCCC(=O)NC(CCCNC(N)=N)C(=O)OCC | 25g | 632288177
Medchemexpress LLC GlyH-101 | 328541-79-3 | MFCD01532954 | 99.7% | 493.15 g/mol | C19H15Br2N3O3 | 10 MG
GlyH-101 is a research-grade small-molecule inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR). It is used in cellular and electrophysiological studies to block CFTR-mediated chloride conductance and has reported antiproliferative activity. Supplied as a purified, characterized compound for laboratory research.
- Potent CFTR inhibitor for cellular and electrophysiology assays.
- Reversible blockade of VSORC conductance.
- High purity (99.7%).
- Molecular weight 493.15 g/mol.
- Molecular formula C19H15Br2N3O3.
- Supplied as a 10 mg vial for research use.
Medchemexpress LLC Sulforhodamine 101 DHPE | 187099-99-6 | >95.0% | 1381.84 | C74H117N4O14PS2 | 1MG
Sulforhodamine 101 DHPE is a red fluorescent phospholipid probe created by conjugating dipalmitoyl phosphoethanolamine to sulforhodamine 101. It readily incorporates into lipid bilayers and is used for membrane imaging, monitoring probe colocalization in liposomes, and detecting protein-ligand interactions on supported bilayers. The dye exhibits excitation/emission peaks near 586/605 nm and is supplied as a powder with recommended cold storage.
Selleck Chemical LLC GlyH-101
GlyH-101 is a selective and reversible CFTR inhibitor with Ki of 4 3 M
![Medchemexpress LLC Benzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl] | 831217-40-4 | 98.2% | 931.12 g/mol | C54H66N4O10 | 1MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238871.png-250.jpg)
Medchemexpress LLC Benzyl 3-[6-[[2-(butylamino)-1-[3-methoxycarbonyl-4-(2-methoxy-2-oxoethoxy)phenyl] | 831217-40-4 | 98.2% | 931.12 g/mol | C54H66N4O10 | 1MG
MAL3-101 is a small-molecule allosteric inhibitor of heat shock protein 70 (HSP70) used in cellular and biochemical research. It inhibits HSP70 ATPase activity by blocking interaction with Hsp40 co-chaperones, perturbing protein folding and proteostasis pathways. The compound is supplied as a high-purity research reagent (CAS 831217-40-4) and is intended for in vitro and preclinical studies only.
- Allosteric inhibitor of HSP70 ATPase activity.
- Blocks Hsp40-Hsp70 interaction to disrupt protein folding.
- Applicable to cellular models studying proteostasis and cancer biology.
- High reported purity supports reproducible results.
- Supplied in small quantities suitable for screening and pilot studies.
- For research use only; not for human or veterinary use.
Medchemexpress LLC Ethyl Lauroyl Argina 5g
Ethyl Lauroyl Arginate Hydrochloride is an arginine derivative[1]