Tricarboxylic acids and derivatives
eMolecules Combi-Blocks Sodium citrate 1kg 290693721 QE-2238 98 000 68-04-2 MFCD00012462 258 068 C6H5Na3O7
Combi-Blocks Sodium citrate 1kg 290693721 QE-2238 98 000 68-04-2 MFCD00012462 258 068 C6H5Na3O7
Medchemexpress LLC Fmoc-nh-peg1-ch2cooh | 260367-12-2 | MFCD06796876 | 99.9% | 341.36 | C19H19NO5 | 5 G
Fmoc-NH-PEG1-CH2COOH is an Fmoc-protected PEG1 linker used as a cleavable linker for antibody-drug conjugate (ADC) synthesis and as a PEG-based PROTAC linker. The compound is supplied as a white powder with reported high purity and is available in multiple pack sizes, including a 5 G pack.
- Fmoc-protected amine with a PEG1 spacer and terminal carboxylic acid.
- Used as a cleavable linker in ADC and PROTAC syntheses.
- Supplied as a white powder; multiple pack sizes available.
- Reported high purity suitable for research applications.
- Chemical identifiers: CAS 260367-12-2; molecular weight 341.36; formula C19H19NO5.
![Research Products International Corp Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 25 KG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00006095-S23040-25000.0.JPG-250.jpg)
Research Products International Corp Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 25 KG
CAS Number: 6132-04-3
Molecular Formula: C6H5Na3O7 • 2H2O
Molecular Weight: 294.1
Selleck Chemical LLC Sodium citrate dihydrate
Sodium citrate dehydrate (Trisodium citrate dihydrate Citric acid trisodium salt dihydrate) is the preferred anticoagulant
Medchemexpress LLC DMAPP (triammonium) | 1186-30-7 | 95.0% | 1 MG
DMAPP (Dimethylallyl diphosphate) triammonium is an isoprenoid precursor found in virtually all life forms. It is an isomer of isopentenyl pyrophosphate (IPP) and plays a role in both the mevalonate and MEP pathways of isoprenoid precursor biosynthesis. The enzyme isopentenyl pyrophosphate isomerase catalyzes the isomerization between DMAPP and IPP.
- Isoprenoid precursor
- Isomer of isopentenyl pyrophosphate (IPP)
- Found in virtually all life forms
- Product of mevalonate and MEP pathways
- Involved in isoprenoid precursor biosynthesis
- Isomerization catalyzed by isopentenyl pyrophosphate isomerase
Medchemexpress LLC Fmoc-NH-PEG6-CH2COOH | 437655-96-4 | 99.2% | 10 G
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound also functions as a PEG-based PROTAC linker for the synthesis of PROTACs, which exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Cleavable ADC linker
- PEG-based PROTAC linker
- Used in the synthesis of antibody-drug conjugates
- Used in the synthesis of PROTACs
- Molecular formula: C29H39NO10
- Molecular weight: 561.62
- Soluble in DMSO at 100 mg/mL (178.06 mM); requires ultrasonic
eMolecules Ambeed / Tris(4-ethynylphenyl)amine / 250mg / 624121628 / A693154 / / 189178-09-4 / MFCD09030768 / 317.391 / C24H15N
Ambeed / Tris(4-ethynylphenyl)amine / 250mg / 624121628 / A693154 / / 189178-09-4 / MFCD09030768 / 317.391 / C24H15N
Medchemexpress LLC PEG3-O-CH2COOH (PROTAC Linker 8) | 51951-05-4 | ≥95.0% | 100 MG
PEG3-O-CH2COOH (PROTAC Linker 8) is a PEG-based PROTAC linker designed for use in the synthesis of SNIPERs. These SNIPERs recruit inhibitor of apoptosis protein (IAP) ubiquitin ligases to specifically degrade targeted proteins, offering a valuable tool for research applications.
- PEG-based PROTAC linker
- Used in the synthesis of SNIPERs
- Recruits inhibitor of apoptosis protein (IAP) ubiquitin ligases
- Designed to specifically degrade targeted proteins
- For research use only
Sigma Aldrich Fine Chemicals Biosciences Sodium citrate tribasic dihydrate BioUltra, for molecular biology | 6132-04-3 | MFCD00150031 | 100G
Sodium citrate tribasic dihydrate BioUltra, for molecular biology | Mol Wt: 294.1 | 6132-04-3 | MFCD00150031 | 100G
Medchemexpress LLC Boc-NH-PEG6-CH2COOH | 391684-36-9 | ≥98.0% | C19H37NO10 | 100 MG
Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. This compound is for research use only and not intended for patient use. It helps exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Molecular weight: 439.50
- Appearance: Colorless to light yellow liquid
- Density: 1.134±0.06 g/cm3
- Shipping at room temperature (continental US)
- Storage (pure form): -20°C for 3 years or 4°C for 2 years
- Storage (in solvent): -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC 3-Thiophenecarboxylic acid, 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methyl-, methyl ester | 544450-68-2 | 99.94% | 337.82 | 100 MG
COR659 is a potent and effective GABAB positive allosteric modulator (PAM) that suppresses alcohol and chocolate self-administration in rats. Its effects are exerted through a composite mechanism, involving positive allosteric modulation of the GABAB receptor and an action at the cannabinoid CB1 receptor.
- Potent and effective GABAB positive allosteric modulator (PAM).
- Suppresses alcohol and chocolate self-administration in rats.
- Exerts effects through a composite mechanism.
- Involves positive allosteric modulation of the GABAB receptor.
- Acts at the cannabinoid CB1 receptor.
- Has shown cytotoxicity against mouse NIH/3T3 cells with an IC50 of 59 μM.
- Relevant to research in neurological, eye or ear disease, neurodegenerative disease, depression, Alzheimer's disease, and Parkinson's disease.
Medchemexpress LLC Dimal-O-CH2COOH | 1620837-47-9 | 96.8% | C13H12N2O7 | 25 MG
diMal-O-CH2COOH is a cleavable ADC linker. It is categorized under Antibody-drug Conjugate/ADC Related and ADC Linker, making it suitable for applications in cancer and cancer targeted therapy.
- Cleavable ADC linker
- White to off-white solid appearance
- Molecular weight: 308.24
- Suitable for antibody-drug conjugate related applications
Medchemexpress LLC Bromo-PEG1-CH2COOH | 1135131-50-8 | >=97.0% | 100 MG
Bromo-PEG1-CH2COOH is a PROTAC linker, designed for use in the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, by connecting an E3 ubiquitin ligase ligand to a target protein ligand.
- Used as a PROTAC linker
- Designed for PROTAC synthesis
- Contains two ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets a protein
- Exploits the ubiquitin-proteasome system
- Enables selective degradation of target proteins
- For research use only
Medchemexpress LLC DiMal-O-CH2COOH | 1620837-47-9 | 96.8% | 308.24 | C13H12N2O7 | 10 MG
This cleavable linker is designed for use in antibody-drug conjugate (ADC) construction and conjugation workflows, offering malemide-based chemistry for attaching payloads to antibodies or targeting moieties. It is provided at research-grade purity and supplied in small quantities suitable for method development and exploratory studies.
- Cleavable linker for ADC construction and conjugation workflows.
- Provides maleimide-based chemistry for reliable payload attachment.
- High purity (96.8%) suitable for research applications.
- Available in small research quantities; larger amounts available on request.
- Store at 4°C, protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
Sigma Aldrich Fine Chemicals Biosciences Sodium citrate tribasic dihydrate for molecular biology, >=99% | 6132-04-3 | MFCD00150031 | 10KG
Sodium citrate tribasic dihydrate for molecular biology, >=99% | Purity: >=99% | Mol Wt: 294.1 | 6132-04-3 | MFCD00150031 | 10KG