Imidazoles

Aromatic organic heterocyclic compounds that consist of a diazole with non-adjacent nitrogen atoms with the formula: C3N2H4.

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1,096 – 1,110 of 5,384 results

1,096

Medchemexpress LLC CDDO-dhTFEA | 1191265-33-4 | 99.64% | 574.72 | 50 MG

CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound that potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB. It restores hypertension (MAP), increases Nrf2 and the expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis, and inflammation in chronic kidney disease (CKD) rats. For research use only, not for sale to patients.

Potently activates Nrf2.
Inhibits the pro-inflammatory transcription factor NF-κB.
Attenuates activation of NF-κB and transforming growth factor-β pathways.
Reduces glomerulosclerosis, interstitial fibrosis, and inflammation in chronic kidney disease (CKD) rats.
Upregulates expression of antioxidant enzymes.
Protects pancreatic tissue and exhibits anti-inflammatory activity.

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1,097

Medchemexpress LLC YM-244769 hydrochlor 25mg | 837424-39-2 | 25MG

YM-244769 hydrochloride is a potent selective and orally active Na /Ca2 exchanger (NCX) inhibitor YM-244769 hydrochloride preferentially inhibits NCX3 and suppresses the unidirectional outward NCX current (Ca2 entry mode) with IC50s of 18 nM and 50 nM respectively YM-244769 hydrochloride efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage YM-244769 hydrochloride can also increase urine volume and urinary excretion of electrolytes in mice[1 [2 [3

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1,098

eMolecules 25743-12-8 | NH-bis(PEG2-OH) | Broadpharm | MFCD29764330 | 281.349 | C12H27NO6 | 98.000 | OCCOCCOCCNCCOCCOCCO | 1g | 303671216

NH-bis(PEG2-OH) | Broadpharm | 25743-12-8 | MFCD29764330 | 281.349 | C12H27NO6 | 98.000 | OCCOCCOCCNCCOCCOCCO | 1g | 303671216

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1,099

eMolecules 155270-99-8 | Medchem Express | Istradefylline | 10mg | 446259409 | HY-10888 | MFCD00928421 | 384.436 | C20H24N4O4

ChemScene | 6-Bromothieno[32-d]pyrimidin-4(3H)-one | 100mg | 712788015 | CS-0360977 | 215927-36-9 | MFCD17677443 | 231.070 | C6H3BrN2OS

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1,100

eMolecules 110505-75-4 | Medchem Express | N6-(4-Hydroxybenzyl)adenosine | 10mg | 446269458 | HY-18775 | MFCD18641957 | 373.369 | C17H19N5O5

Ambeed | (Z)-5-Fluoro-2-((4-oxo-2-(tetrahydropyridazin-1(2H)-yl)thiazol-5(4H)-ylidene)methyl)phenyl pyrrolidine-1-carboxylate | 1mg | 686015720 | A692338 | 1181083-81-7 | MFCD28166314 | 404.460 | C19H21FN4O3S

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1,101

Apexbio Technology LLC Azathioprine 446-86-6 1g

Azathioprine (CAS 446-86-6) is an immunosuppressive prodrug that is metabolized in vivo to 6-mercaptopurine It interferes with purine synthesis leading to the inhibition of DNA RNA and protein synthesis thereby suppressing the proliferation of T and B lymphocytes Azathioprine is widely utilized in biomedical research to study mechanisms of immune modulation graft rejection and the pathophysiology of autoimmune diseases Its ability to modulate adaptive immune responses makes it a valuable tool for investigating immunosuppressive protocols and immune homeostasis in transplantation and autoimmune disorder models

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1,102

Medchemexpress LLC NH-3 | 447415-26-1 | 99.4% | C28H27NO6 | 100 MG

NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. It is derived from the selective thyromimetic GC-1 and inhibits the binding of thyroid hormones to their receptor and also inhibits cofactor recruitment. NH-3 also functions as a click chemistry reagent, featuring an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Orally active, reversible thyroid hormone receptor antagonist
Inhibits thyroid hormone binding to its receptor and cofactor recruitment
Functions as a click chemistry reagent
Contains an alkyne group for copper-catalyzed azide-alkyne cycloaddition
Modestly decreases heart rate in vivo
Inhibits tachycardic and TSH suppressant effects in vivo

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1,103

eMolecules 929095-18-1 | Medchem Express | GSK461364 | 5mg | 446271172 | HY-50877 | MFCD12755419 | 543.61 | C27H28F3N5O2S

Medchem Express | GSK461364 | 5mg | 446271172 | HY-50877 | 929095-18-1 | MFCD12755419 | 543.610 | C27H28F3N5O2S

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1,104

eMolecules 6160-65-2 | Thiocarbonyldiimidazole | ChemScene | MFCD00005289 | 178.210 | C7H6N4S | 98.000 | S=C(n1ccnc1)n1ccnc1 | 5g | 866871416

Thiocarbonyldiimidazole | ChemScene | 6160-65-2 | MFCD00005289 | 178.210 | C7H6N4S | 98.000 | S=C(n1ccnc1)n1ccnc1 | 5g | 866871416

Pricing & Availability

1,105

eMolecules 6160-65-2 | Thiocarbonyldiimidazole | ChemScene | MFCD00005289 | 178.210 | C7H6N4S | 98.000 | S=C(n1ccnc1)n1ccnc1 | 25g | 559782686

Thiocarbonyldiimidazole | ChemScene | 6160-65-2 | MFCD00005289 | 178.210 | C7H6N4S | 98.000 | S=C(n1ccnc1)n1ccnc1 | 25g | 559782686

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1,106

eMolecules 57265-65-3 | Medchem Express | Calmidazolium (chloride) | 5mg | 482203846 | HY-103319 | 687.69 | C31H23Cl7N2O

Medchem Express | Calmidazolium (chloride) | 5mg | 482203846 | HY-103319 | 57265-65-3 | 687.690 | C31H23Cl7N2O

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1,107

Medchemexpress LLC HY-104009A 5mg Medchemexpress, GSK2807 Trifluoroacetate CAS:2245255-66-5 Purity:>98%

Medchemexpress, HY-104009A 5mg GSK2807 Trifluoroacetate CAS:2245255-66-5 GSK2807 Trifluoroacetate is a potent, selective and SAM-competitive inhibitor of SMYD3, with a Ki of 14 nM and an IC50 of 130 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,108

Medchemexpress LLC 2'3'-c-di-AM(PS)2 (Rp,Rp) disodium salt | 1638750-95-4 | 99.4% | 50 MG

2'3'-c-di-AM(PS)2 (Rp,Rp) disodium salt, also known as ADU-S100 disodium salt, is a potent activator of stimulator of interferon genes (STING). This compound is utilized in research related to inflammation, immunology, and cancer studies.

Activates all five human STING alleles.
Induces high expression of IFN-β and pro-inflammatory cytokines.
Shows enhanced type I interferon production.
Demonstrates higher anti-tumor control compared to endogenous ML cGAMP.
Improves long-term survival in tumor models.

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1,109

Medchemexpress LLC M-89 | 2363165-42-6 | 99.1% | 10 MG

M-89 is a highly potent and specific menin inhibitor, with a Kd of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to study MLL leukemia. M-89 inhibits the cell growth in leukemia cell lines carrying MLL fusion.

Inhibits the cell growth of MV4-11 cell line with an IC50 of 25 nM.
Inhibits the cell growth of HL-60 cell line with an IC50 of 10.2 μM.
Stabilized the cellular menin protein in both MV4-11 and MOLM-13 cells dose-dependently (3.7-300 nM).
Induces a time- and dose-dependent apoptosis in MV4-11 cells (0.03-3 μM, 48 h).

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1,110

eMolecules 769109-13-9 | IMIDAZO[1,2-B]PYRIDAZINE-6-CARBOXYLIC ACID | AstaTech | MFCD11044772 | 163.136 | C7H5N3O2 | 95.000 | OC(=O)c1ccc2nccn2n1 | 1g | 449721334

IMIDAZO[1,2-B]PYRIDAZINE-6-CARBOXYLIC ACID | AstaTech | 769109-13-9 | MFCD11044772 | 163.136 | C7H5N3O2 | 95.000 | OC(=O)c1ccc2nccn2n1 | 1g | 449721334

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Imidazoles

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Medchemexpress LLC CDDO-dhTFEA | 1191265-33-4 | 99.64% | 574.72 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC YM-244769 hydrochlor 25mg | 837424-39-2 | 25MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Azathioprine 446-86-6 1g Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NH-3 | 447415-26-1 | 99.4% | C28H27NO6 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-104009A 5mg Medchemexpress, GSK2807 Trifluoroacetate CAS:2245255-66-5 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2'3'-c-di-AM(PS)2 (Rp,Rp) disodium salt | 1638750-95-4 | 99.4% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC M-89 | 2363165-42-6 | 99.1% | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More