Oxadiazoles

Medchemexpress LLC 5-Chloromethyl-1-propyl-1H-imidazole hydrochloride | 497223-15-1 | 95.0% | 195.09 | 100 MG

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5-Chloromethyl-1-propyl-1H-imidazole hydrochloride is a drug intermediate used for the synthesis of various active compounds. It is intended for research use only and not for sale to patients.

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Medchemexpress LLC 4-[5-(4-butylcyclohexyl)-1,2,4-oxadiazol-3-yl]pyridine | 388575-52-8 | MFCD01829706 | 100.0% | 285.38 g·mol⁻¹ | C17H23N3O | 100 MG

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PSN 375963 is a small-molecule agonist of the G protein-coupled receptor GPR119 used as a research tool for in vitro pharmacology. It exhibits micromolar potency and is provided with supporting analytical documentation for use in biochemical and cell-based assays.

• Shows micromolar agonist activity at GPR119 (EC50s 8.4 μM human, 7.9 μM mouse).
• Supplied as a characterized research-grade compound with COA and SDS.
• Available as solid powder and DMSO solutions for assay flexibility.
• High purity suitable for biochemical and cell-based assays.
• Molecular formula C17H23N3O and molecular weight 285.38 g·mol⁻¹.

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eMolecules​ 63417-81-2 | 5-(Chloromethyl)-3-(2-thienyl)-1,2,4-oxadiazole | Combi-Blocks | MFCD03407322 | 200.640 | C7H5ClN2OS | 95.000 | ClCc1nc(no1)-c1cccs1 | 5g | 117575114

5-(Chloromethyl)-3-(2-thienyl)-1,2,4-oxadiazole | Combi-Blocks | 63417-81-2 | MFCD03407322 | 200.640 | C7H5ClN2OS | 95.000 | ClCc1nc(no1)-c1cccs1 | 5g | 117575114

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Medchemexpress LLC 1-Bromo-4-(bromomethyl)benzene-d6 | 229948-68-9 | 99.6% | C7D6Br2 | 5 MG

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1-Bromo-4-(bromomethyl)benzene-d6 is the deuterium labeled 1-Bromo-4-(bromomethyl)benzene. It can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuterium substitution can impact the pharmacokinetic and metabolic profiles of drugs.

• Deuterium labeled compound
• Used as a tracer or internal standard
• Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
• Impacts pharmacokinetic and metabolic profiles of drugs

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Medchemexpress LLC 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | 41443-28-1 | MFCD00792620 | 99.8% | 187.16 g/mol | C9H5N3O2 | 1 ML

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ODQ (1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one) is a potent, selective inhibitor of soluble guanylyl cyclase (sGC) used in research to probe nitric oxide-cGMP signaling and related cellular processes. It is supplied in solution and solid formats for biochemical and cell-based studies.

• Potent and selective inhibitor of soluble guanylyl cyclase (sGC).
• Useful for studying nitric oxide-cGMP signaling in biochemical and cell-based assays.
• Enhances pro-apoptotic effects of cisplatin in certain cell models.
• Available as a 10 mM solution in DMSO (1 mL) and in multiple solid sizes.
• High purity (~99.8%) suitable for research applications.

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Medchemexpress LLC 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | 41443-28-1 | MFCD00792620 | >98.0% | 187.16 | C9H5N3O2 | 5 MG

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ODQ (1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one) is a potent, selective inhibitor of soluble guanylyl cyclase (sGC) used as a research reagent in biochemical and cell-based studies. It blocks NO-activated sGC activity and has been reported to enhance the pro-apoptotic effects of cisplatin in certain cancer cell models. Supplied as a powder for preparation of stock solutions, it is intended for research use only.

• Potent, selective inhibitor of soluble guanylyl cyclase.
• Useful tool compound for studying nitric oxide-sGC signaling.
• Reported to enhance cisplatin-induced apoptosis in some cell models.
• Supplied as a powder suitable for preparing concentrated stock solutions.
• Stable with defined storage recommendations for powder and solutions.

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Medchemexpress LLC Potassium (bromomethyl)trifluoroborate | 888711-44-2 | MFCD09265154 | 200.84 g/mol | BrCH2BF3K | 500 G

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Potassium (bromomethyl)trifluoroborate (CAS 888711-44-2) is an organoboron reagent used as a boron-containing building block in organic synthesis. It is provided as a stable potassium trifluoroborate salt that simplifies handling and storage compared with some boronic acids, and is commonly employed in palladium-catalyzed transformations and modular assembly of complex molecules.

• Organoboron building block for cross-coupling reactions.
• Potassium trifluoroborate salt provides enhanced stability and ease of handling.
• Solid form suitable for accurate weighing and storage.
• Compatible with typical palladium-catalyzed conditions used in synthesis.
• Supplied with a specified purity; verify certificate of analysis before use.

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Medchemexpress LLC Potassium (bromomethyl)trifluoroborate | 888711-44-2 | MFCD09265154 | ≥97.0% | 200.84 g/mol | CH2BBrF3K | 1 G

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Potassium (bromomethyl)trifluoroborate is a potassium organotrifluoroborate reagent used as a building block in organic synthesis and life-science research. It is typically supplied as a white to off-white powder for laboratory use and is applied in cross-coupling reactions and related transformations.

• High purity suitable for research applications (NMR ≥97.0%).
• Molecular formula CH2BBrF3K; molecular weight ~200.84 g/mol.
• White to off-white powder for convenient handling and storage.
• Commonly used as a coupling partner in cross-coupling and synthetic transformations.
• Supplied with batch COA and SDS for quality and safety information.

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Medchemexpress LLC Potassium (bromomethyl)trifluoroborate | 888711-44-2 | MFCD09265154 | 97.0% | 200.84 g/mol | BrCH2BF3K | 10 G

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Potassium (bromomethyl)trifluoroborate is an organotrifluoroborate reagent supplied as the potassium salt and commonly used in organic synthesis as a stable, crystalline building block for cross-coupling and functionalization reactions. It is handled as a solid reagent for laboratory research and is typically stored cool and dry.

• Organoboron reagent for cross-coupling reactions.
• Stable potassium trifluoroborate salt in solid form.
• Useful as a bromomethyl transfer building block in synthesis.
• Suitable for medicinal chemistry and method development.
• Typical appearance: white to almost white powder or crystals.
• Store in a cool, dry place to maintain stability.

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eMolecules​ 1715-13-5 | 4-[(2-Thienylmethyl)amino]benzoic acid | Oakwood Chemical | MFCD00475037 | 233.290 | C12H11NO2S | 98.000 | OC(=O)c1ccc(NCc2cccs2)cc1 | 100mg | 537722107

4-[(2-Thienylmethyl)amino]benzoic acid | Oakwood Chemical | 1715-13-5 | MFCD00475037 | 233.290 | C12H11NO2S | 98.000 | OC(=O)c1ccc(NCc2cccs2)cc1 | 100mg | 537722107

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eMolecules​ 229625-50-7 | DI-TERT-BUTYL CHLOROMETHYL PHOSPHATE (CONTAINS 2-5%K2CO3 AS STABILIZER) | AstaTech | MFCD12165895 | 258.680 | C9H20ClO4P | 95.000 | CC(C)(C)OP(=O)(OCCl)OC(C)(C)C | 1kg | 929740861

DI-TERT-BUTYL CHLOROMETHYL PHOSPHATE (CONTAINS 2-5%K2CO3 AS STABILIZER) | AstaTech | 229625-50-7 | MFCD12165895 | 258.680 | C9H20ClO4P | 95.000 | CC(C)(C)OP(=O)(OCCl)OC(C)(C)C | 1kg | 929740861

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Apexbio Technology LLC ODQ 41443-28-1 50mg

ODQ (CAS 41443-28-1) is a selective inhibitor of soluble guanylate cyclase (sGC) interfering with nitric oxide (NO)-dependent intracellular signaling by blocking sGC-mediated catalysis of cyclic guanosine monophosphate (cGMP) synthesis This inhibition results in reduced cGMP production and subsequent modulation of protein kinase G-regulated cellular processes Studies have demonstrated that ODQ enhances cisplatin-induced apoptosis in human mesothelioma cells in vitro supporting its use in investigating tumor cell apoptosis mechanisms and evaluating synergistic effects in anticancer drug research

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Medchemexpress LLC 6-Bromo-2-(bromomethyl)-3-fluoropyridine | 1187836-89-0 | 96.79% | 268.91 | 50 MG

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6-Bromo-2-(bromomethyl)-3-fluoropyridine is a biological molecule intended for research use only. It is not for human use or sale to patients.

• Appearance: Solid
• Color: White to off-white
• Shipping: Room temperature in continental US; may vary elsewhere
• Storage: 4°C, protect from light. In solvent: -80°C, 6 months; -20°C, 1 month (protect from light)

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Medchemexpress LLC 1-bromo-4-(bromomethyl)benzene-d6 | 229948-68-9 | MFCD22565819 | 99.6% | 255.97 | C7D6Br2 | 10 MG

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1-Bromo-4-(bromomethyl)benzene-d6 is a deuterium-labeled benzyl bromide supplied as a powder for research use. It is used as an isotopically labeled standard and synthetic intermediate in organic and medicinal chemistry, offering high purity for analytical and synthetic workflows.

• Deuterium-labeled benzyl bromide for use as an isotopically labeled standard.
• Molecular formula C7D6Br2 and molecular weight 255.97.
• High purity (99.56%) suitable for analytical applications.
• Supplied as a powder with recommended cold storage for stability.
• Available in small milligram quantities for research-scale use.

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Medchemexpress LLC 1-Bromo-4-(bromomethyl)benzene-d6 | 229948-68-9 | 99.6% | C7D6Br2 | 50 MG

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1-Bromo-4-(bromomethyl)benzene-d6 is the deuterium labeled 1-Bromo-4-(bromomethyl)benzene. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs.

• Can be utilized as a tracer in various studies.
• Functions as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS.
• Incorporation of stable heavy isotopes can aid in quantitation during drug development processes.
• Deuteration offers the potential to influence the pharmacokinetic and metabolic profiles of pharmaceutical compounds.

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