Pyrazoles
![eMolecules 124004-31-5 | 5-Amino-1H-pyrazole-3-carboxylic acid | Combi-Blocks, Inc. | MFCD09263793 | 127.103 | C4H5N3O2 | 97.000 | Nc1cc(n[nH]1)C(O)=O | 25g | 603147138](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502188295.JPG-250.jpg)
eMolecules 124004-31-5 | 5-Amino-1H-pyrazole-3-carboxylic acid | Combi-Blocks, Inc. | MFCD09263793 | 127.103 | C4H5N3O2 | 97.000 | Nc1cc(n[nH]1)C(O)=O | 25g | 603147138
5-Amino-1H-pyrazole-3-carboxylic acid | Combi-Blocks, Inc. | 124004-31-5 | MFCD09263793 | 127.103 | C4H5N3O2 | 97.000 | Nc1cc(n[nH]1)C(O)=O | 25g | 603147138
![eMolecules 55904-61-5 | Ethyl 4-amino-1h-pyrazole-5-carboxylate | Combi-Blocks | MFCD06739331 | 155.157 | C6H9N3O2 | 97.000 | CCOC(=O)c1[nH]ncc1N | 1g | 448003360](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502187822.JPG-250.jpg)
eMolecules 55904-61-5 | Ethyl 4-amino-1h-pyrazole-5-carboxylate | Combi-Blocks | MFCD06739331 | 155.157 | C6H9N3O2 | 97.000 | CCOC(=O)c1[nH]ncc1N | 1g | 448003360
Ethyl 4-amino-1h-pyrazole-5-carboxylate | Combi-Blocks | 55904-61-5 | MFCD06739331 | 155.157 | C6H9N3O2 | 97.000 | CCOC(=O)c1[nH]ncc1N | 1g | 448003360
Medchemexpress LLC ASAH1 Human His-SU 100ug
Recombinant human ASAH1 (acid ceramidase 1) supplied as an N-SUMO/6xHis-tagged protein, expressed in Escherichia coli and provided lyophilized for research use (100 μg). It hydrolyzes ceramide into sphingosine and fatty acids at acidic pH and includes formulation and storage guidance to preserve stability.
- Recombinant human enzyme supplied as N-SUMO and N-6xHis tagged protein.
- Expressed in Escherichia coli and purified to >90% as determined by reducing SDS-PAGE.
- Molecular weight approximately 58.7 kDa.
- Lyophilized from 10 mM Tris-HCl, 1 mM EDTA, 6% trehalose, pH 8.0.
- Unit size 100 μg; do not reconstitute to a concentration below 100 μg/mL.
- Enzyme activity testing is in progress; activity is not guaranteed.
- Store lyophilized material at -20°C; after reconstitution keep at 4°C for up to 1 week or at -20°C for long-term storage and avoid repeated freeze-thaw.
Frontier Specialty Chemicals 5G 1-METHYL-1H-INDAZOLE-6-BORO
1-Methyl-1H-indazole-6-boronic acid; CAS: 1150114-80-9; 5g
Medchemexpress LLC EPHX1 Human His-SU 20ug
Recombinant human EPHX1 (epoxide hydrolase 1) is provided as a purified, N-terminal His-SUMO-tagged protein expressed in E. coli for use in biochemical characterization, enzyme assays, and lipid metabolism research. It catalyzes hydrolysis of aromatic and aliphatic epoxides and supports studies of xenobiotic biotransformation and endogenous lipid signaling.
- N-terminal His-SUMO tag for efficient purification and improved solubility.
- High purity (>90%) by reducing SDS-PAGE for reliable assay performance.
- Approximately 66 kDa molecular weight for size reference in analyses.
- Low endotoxin level (<1 EU/μg) suitable for sensitive biochemical assays.
- Available in small quantities (20 μg, 50 μg, 100 μg) for screening and pilot studies.
Medchemexpress LLC Allopurinol (standard) | 315-30-0 | 100.0% | 100 MG
Allopurinol (Standard) is the analytical standard of Allopurinol, intended for research and analytical applications. It is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 μM. This compound is used in the research of hyperuricemia and gout. It decreases the expression of HIF-1α and HIF-2α protein, and exhibits anti-depressant, anti-nociception, and anti-leishmanial activities. As an analytical standard, it serves as a reference for qualitative, quantitative, and methodological research experiments.
- Analytical standard for research and analytical applications
- Potent and orally active xanthine oxidase inhibitor
- Supports research on hyperuricemia and gout
- Decreases expression of HIF-1α and HIF-2α protein
- Exhibits anti-depressant, anti-nociception, and anti-leishmanial activities
- Reference standard for assay in HPLC, GC, and MS experiments
![eMolecules 847573-68-6 | 1H-PYRAZOLE-3,5-DICARBONITRILE | AstaTech | MFCD28168072 | 118.099 | C5H2N4 | 95.000 | N#Cc1cc([nH]n1)C#N | 1g | 273170353](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502182273.JPG-250.jpg)
eMolecules 847573-68-6 | 1H-PYRAZOLE-3,5-DICARBONITRILE | AstaTech | MFCD28168072 | 118.099 | C5H2N4 | 95.000 | N#Cc1cc([nH]n1)C#N | 1g | 273170353
1H-PYRAZOLE-3,5-DICARBONITRILE | AstaTech | 847573-68-6 | MFCD28168072 | 118.099 | C5H2N4 | 95.000 | N#Cc1cc([nH]n1)C#N | 1g | 273170353
SMOLECULE INC NP-O-SU 1G
CAS NO: 75679-31-1IUPAC Name(2,5-dioxopyrrolidin-1-yl) 2-(4-hydroxy-3-nitrophenyl)acetateMolecular FormulaC12H10N2O7Molecular Weight294.22 g/molInChIInChI=1S/C12H10N2O7/c15-9-2-1-7(5-8(9)14(19)20)6-12(18)21-13-10(16)3-4-11(13)17/h1-2,5,15H,3-4,6H2InChI KeyWXEZCVSZMLAVNV-UHFFFAOYSA-NSMILESC1CC(=O)N(C1=O)OC(=O)CC2=CC(=C(C=C2)O)[N+](=O)[O-]Synonyms4-hydroxy-3-nitrophenylacetyl-O-succinimide ester, NP-O-SU, NP-O-succinimide
eMolecules 1159511-24-6 | 1-(1-Methyl-1H-indazol-5-yl)ethanone | Combi-Blocks, Inc. | MFCD11869767 | 174.203 | C10H10N2O | 98.000 | CC(=O)c1ccc2n(C)ncc2c1 | 1g | 603136090
1-(1-Methyl-1H-indazol-5-yl)ethanone | Combi-Blocks, Inc. | 1159511-24-6 | MFCD11869767 | 174.203 | C10H10N2O | 98.000 | CC(=O)c1ccc2n(C)ncc2c1 | 1g | 603136090
Medchemexpress LLC Allopurinol (Standard) | 315-30-0 | 99.9% | 50 MG
Allopurinol (Standard) is the analytical standard of Allopurinol, intended for research and analytical applications. It is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 μM. It can be used in the research of hyperuricemia and gout, and also decreases the expression of HIF-1α and HIF-2α protein. Allopurinol shows anti-depressant, anti-nociception activity, and anti-leishmanial effect. The compound is a reference standard supplied for assay and is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard for Allopurinol
- Potent and orally active xanthine oxidase inhibitor
- Used in research of hyperuricemia and gout
- Decreases expression of HIF-1α and HIF-2α protein
- Shows anti-depressant and anti-nociception activity
- Anti-leishmanial effect
- Commonly used in HPLC, GC, and MS experiments
Medchemexpress LLC DIM-C-pPhOH | 151358-47-3 | 99.0% | 338.40 | 1 MG
DIM-C-pPhOH | 151358-47-3 | 99.0% | 338.40 | 1 MG
eMolecules 1701-20-8 | 4-Hydroxy-6-methyl-2-(trifluoromethyl)quinoline | Oakwood Chemical | MFCD00153192 | 227.186 | C11H8F3NO | 97.000 | Cc1ccc2nc(cc(O)c2c1)C(F)(F)F | 1g | 537667964
4-Hydroxy-6-methyl-2-(trifluoromethyl)quinoline | Oakwood Chemical | 1701-20-8 | MFCD00153192 | 227.186 | C11H8F3NO | 97.000 | Cc1ccc2nc(cc(O)c2c1)C(F)(F)F | 1g | 537667964
eMolecules 1823327-58-7 | 2-Fluoro-6-hydroxy-4-(trifluoromethyl)benzaldehyde | Apollo Scientific | MFCD27975486 | 208.112 | C8H4F4O2 | 95.000 | Oc1cc(cc(F)c1C=O)C(F)(F)F | 1g | 562429245
2-Fluoro-6-hydroxy-4-(trifluoromethyl)benzaldehyde | Apollo Scientific | 1823327-58-7 | MFCD27975486 | 208.112 | C8H4F4O2 | 95.000 | Oc1cc(cc(F)c1C=O)C(F)(F)F | 1g | 562429245
eMolecules 28456-54-4 | 2-Mercapto-5,6-dimethylpyrimidin-4-ol | MFCD00269435 | 1g
Ambeed | 1-Fluoro-2-iodo-3-methoxybenzene | 250mg | 572829030 | A389275 | 7079-54-1 | MFCD03788539 | 252.027 | C7H6FIO
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Medchemexpress LLC Phenol, 4-(di-1H-indol-3-ylmethyl)- | 151358-47-3 | 98.1% | 338.40 | 25 MG
DIM-C-pPhOH is a nuclear receptor 4A1 (NR4A1) antagonist. It inhibits cancer cell growth and mTOR signaling, and induces apoptosis and cellular stress. It reduces cell proliferation with IC50 values of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells.
- Nuclear receptor 4A1 (NR4A1) antagonist
- Inhibits cancer cell growth and mTOR signaling
- Induces apoptosis and cellular stress
- Reduces cell proliferation in ACHN and 786-O cells
- Inhibits NR4A1-regulated expression (survivin, bcl-2, EGFR)
- Induces sestrin 2, activates AMPKα, inhibits mTOR and downstream kinases
- Decreases β1-integrin protein, mRNA, and β1-integrin-dependent responses in MCF7, MDA-MB-231, and SKBR3 cells
- Inhibits migration of MDA-MB-231 and SKBR3 cells
- Significantly inhibits tumor growth in male athymic nude mice (ACHN cells)