Thiazoles
Aobchem 2-(3-Ethyl-2-methylphenyl)propan-2-ol | 95% | C12H18O | 1g
2-(3-Ethyl-2-methylphenyl)propan-2-ol | 95% | C12H18O | 1g
Aobchem 2-Methoxy-5-thiazolecarboxylic acid | ≥95% | CAS 716362-09-3 | C5H5NO3S | 1g
2-Methoxy-5-thiazolecarboxylic acid | ≥95% | CAS 716362-09-3 | C5H5NO3S | 1g
Aobchem 2-Methoxy-5-thiazolecarboxylic acid | ≥95% | CAS 716362-09-3 | C5H5NO3S | 500mg
2-Methoxy-5-thiazolecarboxylic acid | ≥95% | CAS 716362-09-3 | C5H5NO3S | 500mg
Aobchem 2-(3-Ethyl-4-methylphenyl)propan-2-ol | 95% | CAS 40180-54-9 | C12H18O | 250mg
2-(3-Ethyl-4-methylphenyl)propan-2-ol | 95% | CAS 40180-54-9 | C12H18O | 250mg
Aobchem 2-Ethyl-5-thiazolecarboxylic acid | ≥95% | CAS 30709-68-3 | C6H7NO2S | 250mg
2-Ethyl-5-thiazolecarboxylic acid | ≥95% | CAS 30709-68-3 | C6H7NO2S | 250mg
Medchemexpress LLC Agi-5198 (idh-c35) | 1355326-35-0 | 99.9% | 462.56 | 1 ML
AGI-5198 (IDH-C35) is a potent and selective mutant IDH1R132H inhibitor with an IC50 of 0.07 μM.
- Demonstrates dose-dependent inhibition of mutant IDH1 enzyme in TS603 glioma cells.
- Does not impair colony formation of patient-derived glioma lines expressing only wild-type IDH1.
- Reverses increased reactive oxygen species, DNA double-strand breaks, and cell death in IDH1(R132H) cancer cells exposed to ionizing radiation.
- Causes 50 to 60% growth inhibition of human glioma xenografts in vivo.
- Reduces Ki-67 protein staining in tumors from treated mice.
- Does not affect the growth of IDH1 wild-type glioma xenografts.
Medchemexpress LLC JQ-1 (carboxylic acid) | 202592-23-2 | 99.7% | 400.88 | 50 MG
JQ-1 carboxylic acid is a potent BET bromodomain inhibitor, derived from (+)-JQ-1. It is utilized for synthesizing PROTACs that target the degradation of BRD4. This compound is an off-white to yellow solid with a molecular weight of 400.88 and the chemical formula C19H17ClN4O2S.
- Potent BET bromodomain inhibitor.
- Used to synthesize PROTAC, targeting BRD4 degradation.
- Soluble in DMSO (100 mg/mL).
- Downregulates PD-L1 expression on B16F10 cells in vitro.
- Applicable in various disease areas including cancer, and signaling pathways such as epigenetics and immunology/inflammation.
- Store powder at -20°C for 3 years or 4°C for 2 years.
Medchemexpress LLC 5-Azidopentanoic acid | 79583-98-5 | 99.77% | 25 MG
5-Azidopentanoic acid (also known as 5-Azidovaleric acid) is an organic acid primarily utilized in click chemistry reactions. It is intended for research use only and is not sold for patient administration.
- Organic acid
- Suitable for click chemistry reactions
- For research use only
- Categorized as a biochemical assay reagent
- Purity of 99.77%
- Light yellow to brown liquid appearance
Medchemexpress LLC Aminothiazole (2-aminothiazole) | 96-50-4 | MFCD00005325 | 99.8% | 100.14 g/mol | C3H4N2S | 100G
Aminothiazole (2-aminothiazole, CAS 96-50-4) is a heterocyclic amine used as a versatile building block in organic synthesis. It is employed as a precursor for sulfur-containing agents and biologically active molecules, and can act as a reaction accelerator. The compound has molecular formula C3H4N2S, molecular weight 100.14 g/mol, and is supplied as a white to off-white crystalline solid with high analytical purity.
Medchemexpress LLC AGI-5198 | 1355326-35-0 | 99.9% | 462.56 | 50 MG
AGI-5198 (IDH-C35) is a potent and selective mutant IDH1R132H inhibitor with an IC50 of 0.07 μM. It is designed for research use only.
- Potent and selective mutant IDH1R132H inhibitor.
- Inhibits mutant IDH1 enzyme in TS603 glioma cells.
- Does not impair colony formation of wild-type IDH1 glioma lines.
- Reverses increased reactive oxygen species, DNA double-strand breaks, and cell death after ionizing radiation in IDH1(R132H) mutated cancer cells.
- Causes significant growth inhibition of human glioma xenografts in vivo.