Thiazoles
Medchemexpress LLC JQ-1 (carboxylic acid) | 202592-23-2 | 99.7% | C19H17ClN4O2S | 10 MM/1 ML
JQ-1 carboxylic acid is a derivative of (+)-JQ-1 and functions as a potent BET bromodomain inhibitor. It can be utilized in the synthesis of PROTAC to target the degradation of BRD4.
- Potent BET bromodomain inhibitor
- Used in the synthesis of PROTAC
- Targets degradation of BRD4
- Off-white to yellow solid appearance
- Stable under recommended storage conditions
- High purity (99.69%)
eMolecules 1017781-52-0 | 4-Bromothiazole-2-carbonitrile | MFCD09607690 | 1g
Pharmablock | 3-bromo-5-chloro-2-methoxypyridine | 250mg | 551092444 | PB90954 | 102830-75-1 | MFCD08059322 | 222.470 | C6H5BrClNO
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Medchemexpress LLC Eth 157 | 61595-77-5 | 556.65 | 25 MG
ETH 157 is a Na+ ionophore that induces a Na+/Ca2+ selectivity in membranes. This product is for research use only.
- Acts as a Na+ ionophore
- Induces Na+/Ca2+ selectivity in membranes
- Targets the sodium channel
- Pathway: membrane transporter/ion channel
- Store powder at -20°C for 3 years, or 4°C for 2 years
- Store in solvent at -80°C for 6 months, or -20°C for 1 month
Medchemexpress LLC Acoramidis hydrochloride | 2242751-53-5 | 98.7% | 328.77 | 50 MG
Acoramidis (AG10) hydrochloride is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). It is utilized in the study of transthyretin amyloidosis. This compound demonstrates equal efficacy in stabilizing V122I- and WT-TTR and surpasses tafamidis in stabilizing both WT and mutant TTR in whole serum. Additionally, it exhibits minimal inhibition of common drug discovery off-targets like the hERG potassium ion channel and cytochrome P450 isozymes, indicating low toxicity.
- Stabilizes WT and V122I-TTR.
- Used in the study for transthyretin amyloidosis.
- Shows minimal inhibition of hERG and cytochrome P450 isozymes, suggesting low toxicity.
Chemscene ChemScene | (1-Methylcyclobutyl)methanamine hydrochloride | 5G | CS-0045540 | 0.98 | 1245647-53-3| MFCD18074449 | 135.64
ChemScene | (1-Methylcyclobutyl)methanamine hydrochloride | 5G | CS-0045540 | 0.98 | 1245647-53-3| MFCD18074449 | 135.64
Medchemexpress LLC Filastatin | 431996-53-1 | MFCD03058358 | 99.3% | 359.8 g/mol | C18H18ClN3O3 | 50MG
Filastatin is a small-molecule antifungal research reagent that inhibits Candida albicans filamentation and adhesion. It blocks the yeast-to-hyphal morphological transition and inhibits adhesion across multiple pathogenic Candida species (IC50 ≈ 3 μM in a GFP-based adhesion assay), making it suitable for in vitro studies of fungal morphogenesis and host-pathogen interactions.
- Inhibits Candida albicans filamentation and adhesion.
- Reduces fungal adhesion to surfaces and human cells.
- Blocks the yeast-to-hyphal morphological transition.
- Useful for in vitro antifungal and pathogenesis research.
- High purity appropriate for biochemical assays.