Thiazoles
Medchemexpress LLC c-Met-IN-15 | 330572-32-2 | 98.5% | 299.26 | 5 MG
c-Met-IN-15 (compound S3) is a c-Met kinase inhibitor. It inhibits c-Met kinase activity.
- Inhibits c-Met kinase activity of 21.1% at the concentration of 10 μM.
- For research use only.
eMolecules AstaTech / 24-DICHLORO-6-(METHYLTHIO)-135-TRIAZINE / 0.25g / 256638684 / 31051 / 95.000 / 13705-05-0 / MFCD01679001 / 196.050 / C4H3Cl2N3S
AstaTech / 24-DICHLORO-6-(METHYLTHIO)-135-TRIAZINE / 0.25g / 256638684 / 31051 / 95.000 / 13705-05-0 / MFCD01679001 / 196.050 / C4H3Cl2N3S
Medchemexpress LLC Met-12 | 1242964-46-0 | 99.66% | 1462.65 | 10 MG
Met-12 is a small peptide inhibitor known for its action on the Fas receptor. This compound effectively inhibits Fas receptor-mediated photoreceptor cell apoptosis, making it a valuable tool for relevant research. Furthermore, Met-12 has been observed to reduce Caspase activation, contributing to its potential therapeutic applications in fields related to cell death and ocular health.
- Inhibits Fas receptor-mediated photoreceptor cell apoptosis
- Reduces Caspase activation
- Useful in photoreceptor research
TARGETMOL CHEMICALS INC VH-298 10MG
Also available in 1 mL, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. VH-298 is a potent inhibitor of VHL that stabilizes HIF-alpha and elicits a hypoxic response via a different mechanism, that is the blockade of the VHLHIF-alpha protein-protein interaction downstream of HIF-alpha hydroxylation by PHD enzymes. Purity 100%
Medchemexpress LLC Maralixibat chloride | 228113-66-4 | 99.61% | 710.41 | 50 MG
Maralixibat chloride is an orally active ileal bile acid transporter (IBAT) inhibitor. It is used for the research of rare cholestatic liver diseases such as Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC), and biliary atresia. Studies have shown Maralixibat chloride to reduce elevated sBA levels, improve liver function, and decrease liver tissue damage in a rat model of cholestasis.
- Orally active ileal bile acid transporter (IBAT) inhibitor
- Used for research of rare cholestatic liver diseases
- Reduces elevated sBA levels
- Improves liver function
- Reduces liver tissue damage in cholestasis models
Medchemexpress LLC Endo S2 S. pyogenes 5ug | 5ug
Endo S2 secreted by Streptococcus pyogenes deglycosylates the conserved N-linked glycan at Asn297 on IgG Fc to eliminate its effector functions and evade the immune system EndoS2 specifically hydrolyzes diverse glycans on the Fc region of IgG antibodies using a mechanism that relies on its glycoside hydrolase domain and a coevolved carbohydrate-binding module[1][2] Endo S2 Protein S pyogenes (His) is the recombinant Endo S2 protein expressed by E coli with N-6 His labeled tag
Medchemexpress LLC Yx-02-030 | 3049076-98-1 | 99.9% | 1267.41 | C66H85Cl2N9O10S | 10 MG
A PROTAC small-molecule degrader that targets MDM2 for research use in biochemical and cell-based assays. It binds MDM2 and recruits the VHL E3 ubiquitin ligase to induce proteasomal degradation of MDM2, disrupting MDM2-p53 interactions.
- High purity (≈99.9%).
- Available as a 10 mg research pack suitable for assay development.
- Potent inhibition of MDM2-p53 binding and VHL engagement in biochemical assays.
- Molecular weight 1267.41; formula C66H85Cl2N9O10S.
- Provided with an SDS for handling and storage guidance.
eMolecules Ambeed / 25-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)ethyl) carbonate / 250mg / 525085963 / A169521 / / 78269-85-9 / MFCD02683467 / 259.333 / C10H17NO5Si
Ambeed / 25-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)ethyl) carbonate / 250mg / 525085963 / A169521 / / 78269-85-9 / MFCD02683467 / 259.333 / C10H17NO5Si
Medchemexpress LLC Methyltetrazine-amine | 1345955-28-3 | MFCD28334555 | 99.4% | 201.23 | C10H11N5 | 5 MG
Methyltetrazine-amine is a tetrazine-based reagent used for site-specific dual functionalization of bioconjugates via inverse electron-demand Diels-Alder (iEDDA) click chemistry. It reacts selectively with strained alkenes to enable efficient bioconjugation, hydrogel crosslinking, and scaffold formation for tissue engineering and biomaterials research.
- High purity suitable for bioconjugation (99.4%).
- Reactive in inverse electron-demand Diels-Alder click reactions.
- Solid, purple to purplish red appearance for easy handling.
- Stable under recommended storage; protect from light.
- Available in small-scale quantities for research use.
BIOHIPPO AAV-TH-GCaMP6s-WPRE-hGH-polyA
Recombinant adeno associated virus expressing GCaMP6s under the TH promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Medchemexpress LLC (3-methyloxiran-2-yl)methanol | 872-38-8 | MFCD00033455 | 95.0% | 88.11 g·mol⁻1 | C4H8O2 | 50 MG
(3-Methyloxiran-2-yl)methanol is an epoxy-containing primary alcohol used as a synthetic building block and drug intermediate for small-molecule research. It has formula C4H8O2 (MW 88.11 g·mol⁻1) and CAS 872-38-8. Typical supplied purity is 95.0% (by NMR), and the product is offered in small research pack sizes.
Selleck Chemical LLC GGTI 298 TFA salt
GGTI 298 is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycle and induce apoptosis
Apexbio Technology LLC KN-93 hydrochloride 1956426-56-4 25mg
KN-93 hydrochloride (CAS 1956426-56-4) is a selective inhibitor of Ca2 /calmodulin-dependent protein kinase II (CaMK II) binding competitively at the calmodulin site with a reported Ki of 0 37 M and an IC50 of 370 nM In isolated gastric parietal cells KN-93 suppresses acid secretion stimulated by carbachol and histamine with IC50 values of 0 15 M and 0 3 M respectively and inhibits mucin-stimulated aminopyrine uptake (IC50 0 6 M) Additionally KN-93 shows inhibitory activity against H /K -ATPase and directly blocks voltage-gated potassium (Kv) channels by promoting C-type inactivation KN-93 is widely used to probe CaMK II signaling and its downstream physiological effects in cellular and electrophysiological studies
Medchemexpress LLC SARS-CoV-2 S2 HEK29 1mg | 1mg
The SARS-Cov-2 S glycoprotein is a SARS-Cov-2 S glycoprotein The amino acid sequence 1261-1267a a of the SARS-Cov-2 S glycoprotein is transmembrane The SARS-Cov-2 S glycoprotein is a highly glycosylated trimer each of which consists of 1260 amino acids (residues 14-1273) divided into four structural domains the n-terminal domain (NTD) the c-terminal domain (CTD also known as the receptor-binding domain RBD) and two subdomains (SD1 and SD2) SARS-CoV-2 S2 Protein (HEK293 His) is the recombinant Virus-derived SARS-CoV-2 S2 protein expressed by HEK293 with C-His labeled tag
Apexbio Technology LLC (±)-Decanoylcarnitine chloride 14919-36-9 50mg
racemic Baclofen -Decanoylcarnitine chloride is a small-molecule modulator targeting cholinergic systems by engaging acetylcholine receptors including nicotinic and muscarinic subtypes It is designed to influence neurotransmission and lipid metabolism racemic Baclofen -Decanoylcarnitine chloride exerts its biological activity primarily through modulation of acetylcholine receptors and inhibition of -aminobutyric acid (GABA) receptor activity thereby attenuating GABA-mediated inhibitory synaptic currents In neuronal cells and cardiac models such acylcarnitine derivatives demonstrate antiarrhythmic properties post-ischemic insult and modulation of pain signaling involving the phospholipase C-inositol triphosphate pathway Based on these pharmacological properties racemic Baclofen -Decanoylcarnitine chloride holds research potential in cardiac arrhythmia and pain modulation applications