These specialty-cut In Situ Plate Sealing Films are expertly designed for precise diffraction analysis directly within crystallization plates. Each seal consists of a durable 25 µm COC (Cyclic Olefin Copolymer) film, paired with a 96-hole adhesive gasket that includes removable liners. This innovative construction ensures a secure and isolated environment for each well, crucial for maintaining crystal integrity and preventing cross-contamination during sensitive experiments. The films are engineered to provide optimal optical clarity for sample visualization and minimal background interference during X-ray diffraction. Ideal for high-throughput crystallography workflows, these seals streamline the process of In Situ data collection, eliminating the need for crystal harvesting and mounting. They facilitate reliable and reproducible results for structural biology applications. Each pack contains 10 seals, offering convenience for laboratory use.