Chromatography Supplies
Medchemexpress LLC PMX 205 | 514814-49-4 | 99.5% | 839.04 | 50 MG
PMX 205 is a potent complement C5a receptor (C5aR; CD88) antagonist. It is orally active and selective.
- Potent complement C5a receptor (C5aR; CD88) antagonist
- Orally active and selective C5aR antagonist
- Extended survival time and reduced end-stage motor scores in a rat model of amyotrophic lateral sclerosis
- Reduced astroglial proliferation in the lumbar spinal cord in a rat model of amyotrophic lateral sclerosis
- Decreased fibrillar plaque load in Tg2576 mice and significantly reduced hyperphosphorylated tau in 3xTg mice in models of Alzheimer's disease
Medchemexpress LLC (E)-Tyrphostin AG 556 | 133550-41-1 | >98.0% | 336.39 g·mol⁻¹ | C20H20N2O3 | 100 MG
(E)-AG 556 is a selective small-molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase used in cell signaling and pharmacology research. It has been shown to inhibit EGFR-dependent signaling and to block lipopolysaccharide (LPS)-induced tumor necrosis factor-alpha (TNF-α) production in cellular assays. Supplied as a purified solid, it is typically prepared as DMSO stock solutions for in vitro experiments.
- Selective inhibitor of EGFR tyrosine kinase.
- Inhibits LPS-induced TNF-α production in cell assays.
- High purity suitable for in vitro research applications.
- Soluble in DMSO for concentrated stock preparation.
- Provided as a solid powder for laboratory use.
Med Vet International Miltex Friction Grip Tungsten Carbide Bur, Crosscut Fissure Straight, 10 Pack, Dfg556
Miltex diamond burs come in a variety of shapes and grits for more flexibility for procedures. Diamond particles are uniform in coverage for optimal cutting performance. Crosscut fissure straight. 10 pack. 556.
Medchemexpress LLC PMX-53 | 219639-75-5 | MFCD07363866 | 99.9% | 896.09 | C47H65N11O7 | 50 MG
PMX-53 is a synthetic peptidic antagonist of the complement C5a receptor (C5aR1/CD88). It is orally active and is used in preclinical research on inflammation, cancer, and atherosclerosis. Reported potency at C5aR1 is approximately 20 nM, and analytical data and storage recommendations are provided with the product documentation.
- Peptidic C5a receptor antagonist.
- Orally active, suitable for in vivo and in vitro studies.
- Potent activity against C5aR1 (IC50 ≈ 20 nM).
- Selective for C5aR1 over C5L2 and C3aR.
- Characterized sequence and molecular weight for analytical use.
- COA available with storage recommendations to preserve stability.
Medchemexpress LLC PMX 205 Trifluoroacetate | 514814-49-4 | MFCD31735786 | 99.50% | 953.06 | 25 MG
PMX 205 Trifluoroacetate is a specific complement C5aR1 isoform antagonist.
- Specific complement C5aR1 isoform antagonist.
- Orally active (in vivo studies).
- Has shown to extend survival time and reduce end-stage motor scores in a rat model of amyotrophic lateral sclerosis.
- Reduces astroglial proliferation in the lumbar spinal cord in a rat model of amyotrophic lateral sclerosis.
- Decreases fibrillar plaque load in murine models of Alzheimer's disease.
- Reduces hyperphosphorylated tau in 3xTg mice.
Crescent Chemical Co Inc Silicon Solution Serva for Siconizing Glass and Metal, 100mL
Silicon Solution Serva for Siconizing Glass and Metal, 100mL, in isopropanol, Suitable for siliconizing UV quartz cuvettes. Storage Conditions: +15 °C TO +30 °C
Trajan Scientific Septa Inlet BTO Premium 50/PK
11 mm OD BTO premium high-temp center guide GC septa PK50
Thomas Scientific Calibration Gas BW CG-QT58-1 5-Gas 58L UN 1959
Calibration Gas BW CG-QT58-1 5-Gas 58L UN 1959
Trajan Scientific Septa Inlet Marathon Long Life 1/EA
11 5 mm OD Marathon long-life center guide GC septa PK25
Thomas Scientific Calibration Gas BW CG-Q58-4 4-Gas 58L UN 1956
Calibration Gas BW CG-Q58-4 4-Gas 58L UN 1956