ELISA Substrates and Reagents
Miltenyi Biotec, Inc. Human R-Spondin 1, research grade
Recombinant human roof plate-specific spondin 1.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
ABclonal Technology Fetuin A/AHSG Rabbit pAb
The protein encoded by this gene is a negatively-charged serum glycoprotein that is synthesized by hepatocytes. The encoded protein consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several processes, including endocytosis, brain development, and the formation of bone tissue. Defects in this gene are a cause of susceptibility to leanness.
Cell Signaling Technology Phospho-c-Kit Tyr703 D12E12 Rabbit mAb BSA and Azide Free 100 ug
Phospho-c-Kit Tyr703 D12E12 Rabbit mAb BSA and Azide Free 100 ug
ABclonal Technology Phospho-NF-kB p65/RelA-S311 Rabbit pAb
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology Phospho-MAX-S11 Rabbit pAb
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.
ABclonal Technology Phospho-MST1-T183-MST2-T180
This gene encodes a serine threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor Cleavage of the protein product by caspase removes the inhibitory C-terminal portion The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis Multiple transcript variants encoding different isoforms have been found for this gene
ABclonal Technology Phospho-PPP1R12A-S507 Rabbit pAb
Myosin phosphatase target subunit 1 (MBS) is a key component of myosin phosphatase, which regulates actin-myosin interactions downstream of the Rho GTPase. RhoA, when active in its GTP-bound form, interacts with MBS to control myosin light chain (MLC) phosphorylation, influencing smooth muscle contraction and nonmuscle cell movement. Rho-kinase, activated by GTP-bound RhoA, phosphorylates and inactivates MBS, reducing myosin phosphatase activity. Overexpression of RhoA or activated RhoA increases MLC phosphorylation. Several transcript variants encoding different isoforms of this gene have been identified.
Miltenyi Biotec, Inc. aTGF-b RII-VioBright R720,h, REA903, 30t
Identification and enumeration of TGF-β RII+ cells by flow cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
Sino Biological Recombinant Human HER3/ERBB3 Protein (ECD, His Tag), HPLC-verified, Endotoxin-Free
A DNA sequence encoding the extracellular domain (Met 1-Thr 643) of human ErbB3 (NP_001973.2) precursor was expressed, with a C-terminal polyhistidine tag.
ABclonal Technology Phospho-Akt-S473 Rabbit pAb
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
American Research Products Inc PrEST Antigen LRRC32
PrEST Antigen LRRC32 antigen APrEST88143 for leucine rich repeat containing 32 Recombinant protein fragment of Human LRRC32
American Research Products Inc PrEST Antigen AHSG
PrEST Antigen AHSG antigen APrEST84500 for alpha-2-HS-glycoprotein Recombinant protein fragment of Human AHSG
ABclonal Technology Phospho-ErbB3/HER3-Y1289
This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases It has a neuregulin binding domain but lacks an active kinase domain so it cannot directly signal into the cell However it forms heterodimers with other EGFR family members that possess kinase activity activating pathways that regulate cell proliferation and differentiation Gene amplification or overexpression is observed in various cancers including prostate bladder and breast tumors Alternate splice variants of this gene encode different isoforms one of which lacks the intermembrane region and is secreted to modulate the activity of the membrane-bound form Additional splice variants have been identified but not fully characterized
ABclonal Technology Phospho-GATA1-S310 Rabbit pAb
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.
ABclonal Technology Phospho-EEF2K-S366 Rabbit pAb
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.