ELISA Substrates and Reagents
ABclonal Technology ErbB3/HER3 Rabbit pAb
This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. It has a neuregulin binding domain but lacks an active kinase domain, so it binds the ligand without transmitting signals via protein phosphorylation. It forms heterodimers with other EGFR family members that have kinase activity, activating pathways for cell proliferation or differentiation. Amplification or overexpression of this gene is linked to various cancers, including prostate, bladder, and breast tumors. Alternative splice variants encoding different isoforms have been identified, including one isoform that lacks the intermembrane region and is secreted to modulate the membrane-bound form’s activity. Other splice variants have been reported but are not fully characterized.
Cayman Chemical ChemerIn-9humnacetate 1mg
A peptide agonist of CMKLR1 and CMKLR2; binds to CMKLR1 and CMKLR2 (IC50s = 1.9 and 2.3 nM, respectively); induces calcium mobilization in HEK293T cells expressing either CMKLR1 or CMKLR2 and the G protein Gα15 at 1 µM
United States Biological Corporation P-NTRPHNYL PHOSP (PNPP), 250ML
ImmunoTek™ p-Nitrophenyl Phosphate (pNPP), 250ml
Cayman Chemical ChemerIn-9humnacetate 5mg
A peptide agonist of CMKLR1 and CMKLR2; binds to CMKLR1 and CMKLR2 (IC50s = 1.9 and 2.3 nM, respectively); induces calcium mobilization in HEK293T cells expressing either CMKLR1 or CMKLR2 and the G protein Gα15 at 1 µM
ABclonal Technology Phospho-NF-kB p65/RelA-T505 Rabbit pAb
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology Phospho-Smad5-S463/S465 Rabbit pAb
The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.
Biolegend ELISpot MAX Deluxe Set Mouse TNF- Reactivity Mouse Apps ELISpot Size 5 Plates
ELISpot MAX Deluxe Set Mouse TNF- Reactivity Mouse Apps ELISpot Size 5 Plates
Apexbio Technology LLC EdU Cell Proliferation Kit (TMB) 500tests
EdU Flow Cytometry Assay Kits (HF594) provides a novel method based on click chemistry specifically CuAAC (copper-catalyzed azide-alkyne cycloaddition) enabling direct measurement of DNA synthesis during the S-phase of the cell cycle The thymidine analog EdU (5-ethynyl-2 -deoxyuridine) can be incorporated directly into DNA strands during DNA synthesis The alkyne group on EdU a biologically inert moiety undergoes highly selective reaction with azide-functionalized dyes via the CuAAC reaction forming a stable 1 2 3-triazole product The EdU Cell Proliferation Kit (TMB) specifically targets proliferating cell DNA by linking EdU with biotin azide followed by incubating with HRP-Streptavidin which binds to biotin The bound HRP then catalyzes a colorimetric reaction with TMB substrate allowing final quantification by spectrophotometric detection This kit is designed for use with cell samples and is not suitable for tissue section analysis
Apexbio Technology LLC EdU Cell Proliferation Kit (TMB) 2000tests
EdU Flow Cytometry Assay Kits (HF594) provides a novel method based on click chemistry specifically CuAAC (copper-catalyzed azide-alkyne cycloaddition) enabling direct measurement of DNA synthesis during the S-phase of the cell cycle The thymidine analog EdU (5-ethynyl-2 -deoxyuridine) can be incorporated directly into DNA strands during DNA synthesis The alkyne group on EdU a biologically inert moiety undergoes highly selective reaction with azide-functionalized dyes via the CuAAC reaction forming a stable 1 2 3-triazole product The EdU Cell Proliferation Kit (TMB) specifically targets proliferating cell DNA by linking EdU with biotin azide followed by incubating with HRP-Streptavidin which binds to biotin The bound HRP then catalyzes a colorimetric reaction with TMB substrate allowing final quantification by spectrophotometric detection This kit is designed for use with cell samples and is not suitable for tissue section analysis
Carbosynth LLC. High sensitivity TMB Peroxidase Substrate (stable stop) slow acting, ready to use in immunoassays
This substrate produces a soluble end product which is blue in color that is quantitated at 650 nm. Use of a stop solution enhances sensitivity 2-4 fold and the resulting yellow solution can be read at 450 nm.
ABclonal Technology Phospho-HSF1-S307 Rabbit pAb
The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phosphorylation, which promotes binding by heat shock protein 90.