ELISA Substrates and Reagents
Cayman Chemical SubstncePELISAntIsRum500dtn
A HAT1 inhibitor (IC50 14.8 UM) selective for HAT1 over KAT2A and p300/CBP-associated factor (PCAF) for which it has no activity KAT5 KAT6B and KAT7 (IC50s >100 >100 and 84.82 UM respectively) CBP and p300 (IC50s 90.41 and 74.25 UM respectively) reduces acetylation of H4K5 and H4K12 in hTert-HME1 mammary epithelial cells at 20 UM reduces the growth of HCC1806 and A549 cells (EC50s 10.4 and 1.9 UM respectively) reduces intratumoral H4K12 acetylation in an A549 mouse xenograft model in a dose-dependent manner reduces tumor growth in an A549 mouse xenograft model at 50 and 100 mg/kg once every three days
Cell Signaling Technology Mitochondrial Membrane Potential Assay Kit (II) 1 Kit
Mitochondrial Membrane Potential Assay Kit (II) 1 Kit
Meso Scale Discovery R-PLEX Human CEACAM-1 ASY
The Meso Scale Discovery R-PLEX Human CEACAM-1 Assay is a multiplex immunoassay panel that allows simultaneous quantitative measurement of CEACAM-1 in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This assay requires 50 L or less sample volume and has a testing time of 3 5 hours The lower limit of detection is 1 15 pg/mL It is available as a kit including a 96-well plate coated with capture antibodies detection antibodies calibrators and controls This assay can aid research on cancer inflammation liver disease and diabetes
Cell Signaling Technology Hyaluronan Complete Tissue Staining Kit Alexa FluorR 488 1 Kit
Hyaluronan Complete Tissue Staining Kit Alexa FluorR 488 1 Kit
ABclonal Technology Phospho-NDRG1-S330 Rabbit pAb
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
ABclonal Technology Phospho-ERK1-T202 + ERK2-T185 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Cayman Chemical NItrotyrosInEIAntIsRum500dtn
Contains polyclonal (rabbit) IgG that detects nitrotyrosine
American Research Products Inc Rat heat shock protein 27 HSP
Rat heat shock protein 27 HSP-27 ELISA Kit from CUSABIO Detection Range 0 78 ng/mL-50 ng/mL Sensitivity 0 195 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Meso Scale Discovery Phospho/Total MEK1/2 WCL5
The Meso Scale Discovery Phospho/Total MEK1/2 Whole Cell Lysate Kit is designed to monitor MEK1/2 phosphorylation and expression in cell signaling studies The kit includes a 96-well plate coated with capture antibodies against total MEK1/2 and phospho-MEK1/2 at Ser217/221 The kit provides all necessary reagents for cell lysis and detection using an electrochemiluminescent readout This allows for high sensitivity quantitation of phospho and total levels of MEK1/2 from cell lysates The kit can be used to study MEK1/2 activation in response to growth factors cytokines and pharmacological MEK inhibitors
Abcam Antibody Diluent 4BI, 6ML
Antibody Diluent 4BI (ab221824) is part of the reagents, controls & accessories range. Abcam offers high-quality biological reagents and tools including antibodies, proteins, assays, cell lines and lysates.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical THUNDRTotal RPS6 TRFRET C 9600
Sandwich TR-FRET immunoassay for semi-quantitative detection of Total Ribosomal Protein S6 (both phosphorylated and non-phosphorylated RPS6) in cell lysates.
ABclonal Technology Phospho-CDK9-T186 Rabbit pAb
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
ABclonal Technology Phospho-ErbB4/HER4-Y1284 Rabbit pAb
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
American Research Products Inc Human Spondin 1 SPON1 ELISA
Human Spondin-1 (SPON1) ELISA kit from CUSABIO Detection Range 0 156 ng/mL-10 ng/mL Sensitivity 0 039 ng/mL Sample serum plasma tissue homogenates Method Sandwich