Protein Molecular Weight Markers
ABclonal Technology MELK Rabbit pAb
Enables calcium ion binding activity, non-membrane spanning protein tyrosine kinase activity, and protein serine/threonine kinase activity. Involved in apoptotic process, cell population proliferation, and protein autophosphorylation. Located in cell cortex and plasma membrane.
ABclonal Technology LMBRD1 Rabbit pAb
This gene encodes a lysosomal membrane protein that may be involved in the transport and metabolism of cobalamin. This protein also interacts with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F.
ABclonal Technology CDS2 Rabbit pAb
Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13.
ABclonal Technology Zip12 Rabbit pAb
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).
ABclonal Technology TRPV6 Rabbit pAb
This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.
Biotium Primary Antibody Neurofilament H rRmdO-20 CF680R 1/EA
Neurofilament-H (rRmdO-20) is a recombinant mouse monoclonal antibody that recognizes Neurofilament-H This CF680R antibody conjugate has been validated in Immunofluorescence CF and reg dyes are Biotiums line of next-generation fluorescent dyes with advantages in brightness and photostability
ABclonal Technology TCTA Rabbit pAb
Involved in negative regulation of osteoclast differentiation and osteoclast fusion. Predicted to be integral component of membrane.
ABclonal Technology NSF Rabbit pAb
Enables PDZ domain binding activity and ionotropic glutamate receptor binding activity. Involved in intracellular protein transport, positive regulation of protein catabolic process, and positive regulation of receptor recycling. Located in Golgi apparatus, cytosol, and plasma membrane. Implicated in developmental and epileptic encephalopathy.
ABclonal Technology Slug Rabbit pAb
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
ABclonal Technology NAB1 Rabbit pAb
Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to act upstream of or within endochondral ossification, nervous system development, and regulation of epidermis development. Predicted to be located in nucleoplasm. Predicted to be active in nucleus.
ABclonal Technology BCMO1 Rabbit pAb
Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules.
Cayman Chemical VItelogenInsturgeon Monc 500uL
An allosteric inhibitor of Bcr-Abl (IC50 0.121 UM) inhibits the Bcr-Abl mutants Bcr-AblG250E Bcr-AblE255V and Bcr-AblM351T (IC50s 4.52 0.38 and 0.93 UM respectively) reduces viral titers in IBV-infected Vero cells at 10 UM increases survival in a recalcitrant mutant Bcr-AblT315I mouse bone marrow transplantation model at 75 mg/kg
Sigma Aldrich Fine Chemicals Biosciences fluorescent IEf-Marker pI
filtered through a 0.45 mum membrane filter
ABclonal Technology PLS1 Rabbit pAb
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5 UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.
ABclonal Technology IPO4 Rabbit pAb
Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Involved in DNA replication-dependent chromatin assembly, DNA replication-independent chromatin assembly, and protein import into nucleus. Located in chromatin. Part of protein-containing complex.