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Apexbio Technology LLC ZD 9379 10mg
ZD 9379 (CAS 170142-20-8) is a small molecule that acts as an antagonist at the glycine-binding site of the NMDA receptor Exhibiting oral bioavailability and capable of crossing the blood-brain barrier ZD 9379 modulates neuronal signaling by inhibiting NMDA receptor-mediated pathways Experimental studies have demonstrated its capacity to suppress functions associated with the central nervous system Due to its pharmacological profile ZD 9379 is primarily employed in the investigation of neurological disease models and the elucidation of NMDA receptor-related mechanisms
![Medchemexpress LLC 2(1H)-Quinolinone, 6-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-methyl- | 140841-32-3 | 99.9% | 397.44 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000365551-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2(1H)-Quinolinone, 6-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-methyl- | 140841-32-3 | 99.9% | 397.44 | 1 MG
ZD 2138 is a selective 5-lipoxygenase inhibitor, suitable for research in areas such as asthma. This product is provided as an off-white to light yellow solid with a high purity.
- High purity: 99.9% (LCMS)
- Off-white to light yellow solid appearance
- Consistent with chemical structure (1H NMR, LCMS)
- Suitable for research use
Medchemexpress LLC ZD-4190 1mg | 1mg
ZD-4190 is a potent orally available inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling used for the treatment of cancer
Medchemexpress LLC ZD-4190 10mg | 10mg
ZD-4190 is a potent orally available inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling used for the treatment of cancer
Apexbio Technology LLC ZD 7288(Synonyms: ZD7288, Zatebradine hydrochloride, HCN channel inhibitor ZD7288), 5mg, CAS: 133059-99-1.
ZD 7288 (CAS 133059-99-1) is a selective inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels These channels mediate Na and K currents notably the hyperpolarization-activated current (I h) contributing to neuronal excitability and rhythmic activity ZD 7288 reduces I h in a concentration-dependent voltage- and time-sensitive manner as demonstrated in rat facial motoneurons (IC 50 0 2 M) and hippocampal CA1 pyramidal neurons Additionally it inhibits T-type calcium currents in rat CA1 pyramidal cells ZD 7288 is utilized in research investigating neuronal excitability mechanisms pain signaling and chronic visceral pain models
Cayman Chemical ZD 7155hydrochlorIde 25mg
An AT1 receptor antagonist (IC50 = 3.3 nM); inhibits angiotensin II-induced pressor responses in conscious normotensive rats; decreases mean arterial pressure in conscious spontaneously hypertensive rats at 1.082 µmol/kg; improves motor nerve conduction velocity in the sciatic nerve in a rat model of streptozotocin-induced diabetic neuropathy at 10 mg/kg in the drinking water; decreases disease severity and NF-κB and AP-1 activation in a mouse model of LPS-induced acute lung injury at 10 mg/kg
Medchemexpress LLC ZD-0892 | 171964-73-1 | 95.0% | 499.52 | 25 MG
ZD-0892 is a selective and potent inhibitor of neutrophil elastase. It exhibits high affinity for human neutrophil elastase and porcine pancreatic elastase, making it suitable for targeted research.
- Selective and potent inhibitor of neutrophil elastase
- Suitable for in vitro and in vivo studies
- Available in solid form for various research needs
- Backed by scientific publications for its applications
Apexbio Technology LLC ZD 7288(Synonyms: ZD7288, Zatebradine hydrochloride, HCN channel inhibitor ZD7288), 10mg, CAS: 133059-99-1.
ZD 7288 (CAS 133059-99-1) is a selective inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels These channels mediate Na and K currents notably the hyperpolarization-activated current (I h) contributing to neuronal excitability and rhythmic activity ZD 7288 reduces I h in a concentration-dependent voltage- and time-sensitive manner as demonstrated in rat facial motoneurons (IC 50 0 2 M) and hippocampal CA1 pyramidal neurons Additionally it inhibits T-type calcium currents in rat CA1 pyramidal cells ZD 7288 is utilized in research investigating neuronal excitability mechanisms pain signaling and chronic visceral pain models
Apexbio Technology LLC ZD 7288(Synonyms: ZD7288, Zatebradine hydrochloride, HCN channel inhibitor ZD7288), 25mg, CAS: 133059-99-1.
ZD 7288 (CAS 133059-99-1) is a selective inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels These channels mediate Na and K currents notably the hyperpolarization-activated current (I h) contributing to neuronal excitability and rhythmic activity ZD 7288 reduces I h in a concentration-dependent voltage- and time-sensitive manner as demonstrated in rat facial motoneurons (IC 50 0 2 M) and hippocampal CA1 pyramidal neurons Additionally it inhibits T-type calcium currents in rat CA1 pyramidal cells ZD 7288 is utilized in research investigating neuronal excitability mechanisms pain signaling and chronic visceral pain models
Cayman Chemical ZD 7155hydrochlorIde 1mg
An AT1 receptor antagonist (IC50 = 3.3 nM); inhibits angiotensin II-induced pressor responses in conscious normotensive rats; decreases mean arterial pressure in conscious spontaneously hypertensive rats at 1.082 µmol/kg; improves motor nerve conduction velocity in the sciatic nerve in a rat model of streptozotocin-induced diabetic neuropathy at 10 mg/kg in the drinking water; decreases disease severity and NF-κB and AP-1 activation in a mouse model of LPS-induced acute lung injury at 10 mg/kg
Medchemexpress LLC ZD-0892 | 171964-73-1 | 95.0% | 499.52 | 1 ML
ZD-0892 is a selective and potent inhibitor of neutrophil elastase, with Ki values of 6.7 nM for human neutrophil elastase and 200 nM for porcine pancreatic elastase. It is intended for research use only and not for sale to patients. The product is a solid, white to off-white in appearance.
- Selective and potent inhibitor of neutrophil elastase.
- Reduces myocardial elastolytic activity and coronary microvascular perfusion injury in DBA/2 mice infected with the EMC virus.
- Decreases the pathologic severity of myocardial lesions associated with murine viral myocarditis.
- Capable of reversing advanced pulmonary vascular disease in rats.
![Medchemexpress LLC 2(1H)-Quinolinone, 6-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-methyl- | 140841-32-3 | 99.9% | 397.44 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000366030-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2(1H)-Quinolinone, 6-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-methyl- | 140841-32-3 | 99.9% | 397.44 | 25 MG
ZD 2138 is a chemical compound identified by CAS No. 140841-32-3. It has a molecular formula of C23H24FNO4 and a molecular weight of 397.44. This compound is typically an off-white to light yellow solid with a high purity of 99.9%.
- Chemical name: 2(1H)-Quinolinone, 6-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-methyl-
- Molecular formula: C23H24FNO4
- Molecular weight: 397.44
- Purity: 99.9%
- Appearance: Off-white to light yellow solid
- Storage (powder): -20°C for 3 years; 4°C for 2 years
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month