MW 412.5 Da, Purity >98%. Potent, selective PKC inhibitor (IC₅₀ values are 0.0084, 0.0180, 0.210, 0.132, and 5.8 μM for α, β1, δ, ε and ζ isoforms respectively). Potent GSK-3 inhibitor (IC₅₀ = 360 nM). Potent 5-HT3 antagonist (Ki = 29.5 nM). Shows anti-inflammatory effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement