Process Flow Controllers
Medchemexpress LLC ARS-853 | 1629268-00-3 | 98.4% | 432.94 | 100 MG
ARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor that targets mutant KRAS-driven signaling. It works by binding to the GDP-bound oncoprotein, thereby preventing its activation.
- Cell-active, selective, covalent KRAS G12C inhibitor
- Inhibits mutant KRAS-driven signaling
- Binds to GDP-bound oncoprotein
- Prevents KRAS activation
- IC50 of 2.5 μM
- Molecular weight of 432.94
- Purity of 98.4%
- Appearance as a solid
- Color is white to off-white
Medchemexpress LLC ARS-1323 | 1698024-73-5 | 430.84 | 100 MG
ARS-1323 is a potent KRAS G12C inhibitor. It specifically binds to the cysteine residue on the mutant K-Ras protein, locking it in the GDP-bound conformation and effectively blocking K-Ras activation and downstream signaling pathways. This compound is valuable for investigating signal transduction mechanisms and growth characteristics of tumor cells driven by K-Ras G12C.
- KRAS G12C inhibitor
- Specifically binds to the cysteine residue on the mutant K-Ras protein
- Blocks K-Ras activation and downstream signaling pathways
- Useful for investigating signal transduction mechanisms
- Useful for studying growth characteristics of K-Ras G12C driven tumor cells
- Supplied as a white to off-white solid
Medchemexpress LLC ARS-1630 | 1698055-86-5 | 430.84 | 25 MG
ARS-1630 is a novel inhibitor of mutant K-ras G12C, derived from patent WO 2015054572 A1. It is characterized as a less active enantiomer of ARS-1620. This compound targets mutant K-ras G12C, which is considered potentially druggable through allele-specific covalent targeting of Cys-12 near an inducible allosteric switch II pocket. This approach relies on the active cycling of KRAS G12C between its active-GTP and inactive-GDP conformations, as the accessibility of the switch II pocket is limited to the GDP-bound state.
- Specifically inhibits mutant K-ras G12C.
- It is a less active enantiomer of ARS-1620.
- Molecular weight: 430.84.
- Chemical formula: C21H17ClF2N4O2.
- Appears as a white to yellow solid.
Med Vet International Jorvet Cage Mounted Humidifier, with Flowmeter and Quick Connect, J0953Q
Jorvet's cage mounted oxygen deliver system with has a flowmeter with humidifier. This oxygen delivery system can attach to any cage. 15LPM flowmeter Bubble humidifier, add water or saline Attaches to cage bars via two U bolts or wide flat washers Choice of male DISS fitting or male Ohio quick release for oxygen hose connection to flowmeter 7ft. Oxygen Tubing 14fr oxygen catheter for nasal insertion ro blow by
Med Vet International Dial Flowmeter w/Female DISS & Male DISS, J0534EFM
Wall style Quick release female DISS flowmeter, can hook right to male DISS i.e. ‘H’ tank regulator. Dial flowmeter 1-15 LPM. Outlet end is a male DISS fitting.
Cole-Parmer COLE-PARMER 0.01 TO 100 MTORR
Cole-Parmer 0.01 to 100 mTorr Pressure/Vacuum Meter for Pirani-Type Sensor
Med Vet International Jorvet O-Ring for 10cc Syringe, J0111ANO
NY, CT, IL, NJ, NH, DE and MN restrict the sale of syringes and needles to licensed professionals and entities. By proceeding to purchase through our website, you acknowledge that you are over 18 years of age.
Med Vet International Jorvet Plunger Plate for 10cc Hauptner Syringe, J0031D12A
Replacement plunger plate for Jorvet 10cc Hauptner syringe.
Med Vet International Jorvet Metal Cover for 10cc Hauptner Syringe, J0031D14A
Replacement metal cover for Jorvet 10cc Hauptner syringe.