Process Flow Controllers
Erdco Engineering Corporation WICKS ERDCO 10/PK
Specification Grade Wicks for Smoke Point test consistancy. Extracted & shipped in a desiccated container. Ten individual wicks per package. ASTM D1322, ASTM D1740, IP 57 & ISO 3014
Medchemexpress LLC Ars-853 | 1629268-00-3 | 98.39% | 432.94 | 1 ML
ARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5 μM. It inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation.
- Cell-active, selective, covalent KRAS G12C inhibitor.
- IC50 of 2.5 μM for KRAS(G12C).
- Inhibits mutant KRAS-driven signaling.
- Reduces GTP-bound KRAS levels by more than 95% at 10 μM in KRASG12C-mutant lung cancer cells.
- Inhibits proliferation with an IC50 similar to its target inhibition IC50.
- Selectively reduces KRAS-GTP levels and RAS-effector signaling in KRASG12C-mutant cells.
- Induces apoptosis in four KRASG12C mutant cell lines.
Medchemexpress LLC ARS-853 | 1629268-00-3 | 98.39% | 432.94 | 25 MG
ARS-853 is a cell-active, selective, and covalent KRAS G12C inhibitor with an IC50 of 2.5 μM. It inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein, thereby preventing its activation.
- Selective KRAS G12C inhibition: designed to bind to KRASG12C with high affinity.
- Potent cellular activity: reduces GTP-bound KRAS levels by over 95% at 10 μM in KRASG12C-mutant lung cancer cells.
- Antiproliferative effects: inhibits proliferation in KRASG12C mutant lung cancer cell lines with an IC50 of 2.5 μM.
- Induces apoptosis in four KRASG12C mutant cell lines.
- Suppresses effector signaling: completely suppresses the effects of exogenous KRASG12C expression on KRAS-GTP levels, KRAS-BRAF interaction, and ERK signaling.
- Intended for research use only.
TARGETMOL CHEMICALS INC ARS-853 5MG
Also available in 1mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM) a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cellspurity: 98%
Cole-Parmer Diba Omnifit Standard Valve for 1 to 4 mm OD Tubing, 3-way, tee, single key; 1/ea
Quickly and easily connect semi-rigid tubing such as PTFE, ETFE, and FEP as well as rigid materials such as glass, PEEK, and stainless steel. Use the interchangeable components to create chemically inert fluid pathway connections and flat-bottom ports (using Gripper fittings). Fittings are autoclavable (remove caps first). Order colored caps quickly and easily color code multiple fluid lines.
Selleck Chemical LLC ARS-1323-E1856-100MG
ARS-1323 is the racemic mixture containing ARS-1620 and a potent inhibitor of mutant KRAS G12C It can be used in research for biochemical binding screens as companion imaging drugs (CID) for KRAS G12C
Sigma Aldrich Fine Chemicals Biosciences DDC Mass Spect GoldR Serum1L
DDC Mass Spect Gold is processed from human plasma using a validated process that reduces the hormone and steroid levels please see average hormone and steroid values below. This process also maintains the inherent characteristics of the human plasma resulting a in a pool that is consistent with patient samples. The human plasma is collected from donors at fDA licensed facilities. Each donor is screened for donor eligibility according to fDA regulations. Each unit is tested for and found negative for HIV1/2-ab HBsAg HCV-ab HIV-1 (NAT) HCV (NAT) and RPR. The plasma is inspected for conformance to raw material specifications. The plasma is processed according to a batch record. The finished product is analyzed and inspected according to quality control procedures for conformance to specifications. Records from donor unit(s) to final product are maintained according to established procedures. These records include donor records raw material inspection records batch records testing