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Instruments designed to measure and/or control the flow of test liquids and gases. Products include process flow computers, flow measurement controllers, and process flowmeters and may be able to record flow data digitally.
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Specification Grade Wicks for Smoke Point test consistancy. Extracted & shipped in a desiccated container. Ten individual wicks per package. ASTM D1322, ASTM D1740, IP 57 & ISO 3014
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ARS-1323 is the racemic mixture containing ARS-1620 and a potent inhibitor of mutant KRAS G12C It can be used in research for biochemical binding screens as companion imaging drugs (CID) for KRAS G12C
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Also available in 1mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor. purity: 98%
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ARS-853 is a selective covalent KRAS(G12C) inhibitor that inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation ARS-853 also induces apoptosis
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ARS-1630 is a novel inhibitor of mutant K-ras G12C, whose properties are derived from patent WO 2015054572 A1. It is a less active enantiomer of ARS-1620 and is supplied as a white to yellow solid.
Inhibits mutant K-ras G12C
Less active enantiomer of ARS-1620
Available in solid form
White to yellow appearance
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ARS-1323 is a KRAS G12C inhibitor that specifically binds to the cysteine residue on the mutant K-Ras protein. This action locks K-Ras in its GDP-bound conformation, blocking activation and downstream signaling pathways. It is suitable for investigating signal transduction mechanisms and growth characteristics in tumor cells driven by K-Ras G12C.
Inhibits KRAS G12C
Blocks K-Ras activation and downstream signaling
Investigates signal transduction mechanisms and growth characteristics
Reduces uptake of [18F]PFPMD by KRAS G12C-mutant H358 NSCLC cells
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