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Filtered Search Results
Medchemexpress LLC XL177A | 2417089-74-6 | 99.6% | 861.47 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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XL177A is a highly potent and selective irreversible USP7 inhibitor with an IC50 of 0.34 nM, demonstrating cancer cell killing through a p53-dependent mechanism. It acts as a potent USP7 inhibitor and p53 stabilizer in vitro, effectively suppressing cancer cell growth. The compound selectively labels the catalytic cysteine, C223, of USP7 across the DUBome and human proteome.
- Highly potent and selective irreversible USP7 inhibitor (IC50 of 0.34 nM).
- Elicits cancer cell killing via a p53-dependent mechanism.
- Suppresses cancer cell growth predominantly through p53-dependent pathways.
- Labels USP7's catalytic cysteine (C223) with exquisite selectivity.
- Induces complete G1 arrest in MCF7 cells after 24 hours (at 1 μM).
- Promotes rapid degradation of HDM2, increasing p53 and p21 protein levels in MCF7 cells.
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eMolecules 116-82-5 | 1-Amino-2-bromo-4-hydroxyanthracene-9,10-dione | MFCD00019156 | 5g
Ambeed | 3-(Bromomethyl)-2-chloro-6-fluoropyridine | 250mg | 752809983 | A1205516 | 1227516-84-8 | MFCD16607615 | 224.460 | C6H4BrClFN
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eMolecules 3,4,5-Trifluoroacetophenone | 220141-73-1 | 1G
Matrix Scientific | 3,4,5-Trifluoroacetophenone | 1G | 220141-73-1 | MFCD07368864 | MW:171.243
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Matrix Scientific 2-ACETYL-5-BROMOTHIOPHENE-25G
2-Acetyl-5-bromothiophene, 99%; 25g,C6H5BrOS, MFCD00014528, mw 205.08, [5370-25-2]
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Sigma Aldrich Fine Chemicals Biosciences Ibuprofen Related Compound C United States Pharmacopeia (USP) Reference Standard | 38861-78-8 | 3X0.2ML
Ibuprofen Related Compound C United States Pharmacopeia (USP) Reference Standard | Mol Wt: 176.25 | 38861-78-8 | 3X0.2ML
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![eMolecules 99-81-0 | 2-Bromo-4'-nitroacetophenone | Combi-Blocks | MFCD00007356 | 244.044 | C8H6BrNO3 | 98.000 | [O-][N+](=O)c1ccc(cc1)C(=O)CBr | 25g | 205390112](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2225381.JPG-250.jpg)
eMolecules 99-81-0 | 2-Bromo-4'-nitroacetophenone | Combi-Blocks | MFCD00007356 | 244.044 | C8H6BrNO3 | 98.000 | [O-][N+](=O)c1ccc(cc1)C(=O)CBr | 25g | 205390112
2-Bromo-4'-nitroacetophenone | Combi-Blocks | 99-81-0 | MFCD00007356 | 244.044 | C8H6BrNO3 | 98.000 | [O-][N+](=O)c1ccc(cc1)C(=O)CBr | 25g | 205390112
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eMolecules 2881-83-6 | Ethyl 3-(4-methoxyphenyl)-3-oxopropanoate | Combi-Blocks | MFCD00449636 | 222.240 | C12H14O4 | 97.000 | CCOC(=O)CC(=O)c1ccc(OC)cc1 | 5g | 249355689
Ethyl 3-(4-methoxyphenyl)-3-oxopropanoate | Combi-Blocks | 2881-83-6 | MFCD00449636 | 222.240 | C12H14O4 | 97.000 | CCOC(=O)CC(=O)c1ccc(OC)cc1 | 5g | 249355689
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eMolecules 769944-39-0 | tert-Butyl 2-(4-chlorophenyl)piperazine-1-carboxylate | MFCD08275679 | 1g
Ambeed | tert-Butyl 2-(4-chlorophenyl)piperazine-1-carboxylate | 1g | 524994021 | A106126 | 769944-39-0 | MFCD08275679 | 296.800 | C15H21ClN2O2
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Medchemexpress LLC Chlorogenic acid butyl ester | 132741-56-1 | 410.42 | 5 MG
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Chlorogenic acid butyl ester is a caffeoylquinic acid and a potent melanogenesis inhibitor. It inhibits the expression of microphtalmia-associated transcription factor (MITF), tyrosinase, tyrosinerelated protein 1 (TRP-1), and TRP-2. It also exhibits antioxidant activity.
- Potent melanogenesis inhibitor
- Inhibits MITF, tyrosinase, TRP-1, and TRP-2 expression
- Shows antioxidant activity
- Exhibits inhibitory activities with 33-62% reduction of melanin content at 100 μM concentration on a-MSH-stimulated B16 melanoma cells with no or almost no toxicity
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Medchemexpress LLC Fitusiran | 1499251-18-1 | 94.7% | C78H139N11O30 | 10MG
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Fitusiran is a small interfering RNA (siRNA) that targets antithrombin (AT) messenger RNA in the liver to lower AT production and thereby increase thrombin generation. It is supplied as a research-grade, chemically modified oligonucleotide for preclinical and biochemical studies in coagulation and hemophilia research.
- Targets antithrombin mRNA to reduce antithrombin levels.
- Increases thrombin generation for coagulation studies.
- Contains chemically modified nucleotides for enhanced stability.
- Provided with reported purity suitable for research use.
- Supplied in small pack sizes for preclinical and in vitro experiments.
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Matrix Scientific 2-ACETYL-3-METHYLTHIOPHENE-5G
2-Acetyl-3-methylthiophene, 98%; 5g,C7H8OS, MFCD00005443, mw 140.21, [13679-72-6]
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Pfaltz & Bauer VALEROPHENONE 99% 5G
Valerophenone 99% 5G CAS# 1009-14-9
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eMolecules 1758-68-5 | 1,2-Diaminoanthraquinone | Combi-Blocks | MFCD00001219 | 238.246 | C14H10N2O2 | 95.000 | Nc1ccc2C(=O)c3ccccc3C(=O)c2c1N | 25g | 448007466
1,2-Diaminoanthraquinone | Combi-Blocks | 1758-68-5 | MFCD00001219 | 238.246 | C14H10N2O2 | 95.000 | Nc1ccc2C(=O)c3ccccc3C(=O)c2c1N | 25g | 448007466
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eMolecules 493-33-4 | 4-HYDROXY-2-METHOXYACETOPHENONE | MFCD00038750 | 1g
Medchem Express | N-Desethyl Sunitinib (hydrochloride) | 5mg | 649421685 | HY-138813 | | 406.890 | C20H24ClFN4O2
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Medchemexpress LLC O-Nornuciferine | 3153-55-7 | 5 MG
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O-Nornuciferine is an aporphine-type alkaloid derived from lotus leaf. It acts as a potent hERG channel inhibitor, exhibiting an IC50 of 7.91 μM in vitro hERG blockages in HEK293 cells. This compound is intended for research use only.
- Potent hERG channel inhibitor
- 99.85% purity
- White to off-white solid appearance
- Store at 4°C, sealed, away from moisture and light
- Soluble in DMSO at 50 mg/mL
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